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The map label for this gene is obg

Identifier: 218532750

GI number: 218532750

Start: 5188142

End: 5189176

Strand: Reverse

Name: obg

Synonym: Mchl_4873

Alternate gene names: 218532750

Gene position: 5189176-5188142 (Counterclockwise)

Preceding gene: 218532751

Following gene: 218532749

Centisome position: 89.81

GC content: 69.47

Gene sequence:

>1035_bases
GTGAAATTCCTCGATGAAGCCAAGGTCTACGTCCGCTCCGGCGACGGCGGTCCCGGCTGCGTCTCGTTCCGGCGGGAAAA
GTTCATCGAGTTCGGCGGGCCGAACGGCGGCGACGGCGGACGGGGCGGCGATGTCTGGATCGAGTGCGTGCAGGGCCTCA
ACACCCTGATCGACTACCGCTACCGGCAGCACTTCAAGGCGAAGAAGGGCGAGCACGGCATGGGCTCGAACTGCCACGGC
GCCAAGGGCGACGACGCGGTGCTTCAGGTGCCGGCGGGCACGCAGGTCTTCGCCGAGGACGGCGAGACGCTGATCGCCGA
CATGACCGAGGTCGGCCAGCGGGTGCGGCTCGCCAAGGGCGGCAATGGCGGCTTCGGCAACGCCTACTTCACCACCTCCA
CGAACCGGGCGCCGCGCCACGCCAATCCCGGCCTGGAAGGCCAGGAAATGTGGCTGATCCTGCGCCTCAAGCTCATCGCC
GATGCCGGCCTCGTCGGCCTGCCGAATGCGGGCAAATCGACCTTCCTGGCGACCGTCACCGCCGCCAAGCCGAAGATCGC
CGACTATCCGTTCACCACCCTCCATCCGGGCCTCGGCGTGGTGCGCTCGGACGAGCGCGAGTTCGTGCTCGCCGACATCC
CCGGCCTGATCGAGGGCGCGCATGAGGGCGTCGGCCTCGGCGACCGCTTCCTCGCCCATGTCGAGCGCTGCCGGGTTCTG
CTCCACCTCGTGGAGGGCACGAGCGAGCATGCCGGCAAGGCCTACAAGCTGGTGCGGCGGGAGTTGGAGGCCTACGGCGA
GGGCCTGTCCGACAAGCCCGAGATCGTCGCCCTCTCAAAGGCGGACGCGCTCGATGCCGACACCCTCAAGCAGCAGCTCG
CCCGGCTGAAGCGGGCGGCGGGCGGCAAGCCGCTGGTGCTCTCGGCGGCCTCTGGGCAGGGCGTGCAGGAGGCTTTGCGC
GCGATCCAGGCCCAGCTTGATACGCAGGGCGCAGAGGAAGCGGAGGCGCAACCCGCCGAGCCCTGGCAACCGTGA

Upstream 100 bases:

>100_bases
AGCGGGCCTGCGCAGCATCCAGTACCTCAATCTCGACGGCCAGTGCCGTCGCACAGAAAGCTGACCGGCCCTCCCGGTCC
AGAATCCAAGGCGAAGCACC

Downstream 100 bases:

>100_bases
GCGCAGCGGCGCTACGCCTCAGTCCGGACCGGCGACGGGATTTGCCGGTTTGCCCTACATCGGATGCATGCGCAGCACCC
TCGCTCTCCTCCTCGCCCTC

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYRYRQHFKAKKGEHGMGSNCHG
AKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKGGNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIA
DAGLVGLPNAGKSTFLATVTAAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVL
LHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAAGGKPLVLSAASGQGVQEALR
AIQAQLDTQGAEEAEAQPAEPWQP

Sequences:

>Translated_344_residues
MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYRYRQHFKAKKGEHGMGSNCHG
AKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKGGNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIA
DAGLVGLPNAGKSTFLATVTAAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVL
LHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAAGGKPLVLSAASGQGVQEALR
AIQAQLDTQGAEEAEAQPAEPWQP
>Mature_344_residues
MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYRYRQHFKAKKGEHGMGSNCHG
AKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKGGNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIA
DAGLVGLPNAGKSTFLATVTAAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVL
LHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAAGGKPLVLSAASGQGVQEALR
AIQAQLDTQGAEEAEAQPAEPWQP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=343, Percent_Identity=39.3586005830904, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=364, Percent_Identity=36.2637362637363, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI111955063, Length=267, Percent_Identity=34.8314606741573, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4758796, Length=151, Percent_Identity=34.4370860927152, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI58761500, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4557537, Length=117, Percent_Identity=35.8974358974359, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=52.7439024390244, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1787454, Length=102, Percent_Identity=38.2352941176471, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=38.5321100917431, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=307, Percent_Identity=29.6416938110749, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17555344, Length=151, Percent_Identity=32.4503311258278, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=109, Percent_Identity=36.697247706422, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=114, Percent_Identity=35.9649122807018, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=163, Percent_Identity=38.6503067484663, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=124, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=114, Percent_Identity=36.8421052631579, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20129375, Length=343, Percent_Identity=35.8600583090379, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24585318, Length=334, Percent_Identity=35.6287425149701, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17981711, Length=151, Percent_Identity=31.1258278145695, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=36.7521367521368, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640873, Length=144, Percent_Identity=31.9444444444444, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640877, Length=144, Percent_Identity=31.9444444444444, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640875, Length=144, Percent_Identity=31.9444444444444, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_METC4 (B7KSH0)

Other databases:

- EMBL:   CP001298
- RefSeq:   YP_002423566.1
- ProteinModelPortal:   B7KSH0
- SMR:   B7KSH0
- GeneID:   7114294
- GenomeReviews:   CP001298_GR
- KEGG:   mch:Mchl_4873
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36692; Mature: 36692

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYR
CCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRQHFKAKKGEHGMGSNCHGAKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHEEEEEC
GNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIADAGLVGLPNAGKSTFLATVT
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEEE
AAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVL
CCCCCCCCCCCHHCCCCCCCEECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAA
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHC
GGKPLVLSAASGQGVQEALRAIQAQLDTQGAEEAEAQPAEPWQP
CCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MKFLDEAKVYVRSGDGGPGCVSFRREKFIEFGGPNGGDGGRGGDVWIECVQGLNTLIDYR
CCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRQHFKAKKGEHGMGSNCHGAKGDDAVLQVPAGTQVFAEDGETLIADMTEVGQRVRLAKG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHEEEEEC
GNGGFGNAYFTTSTNRAPRHANPGLEGQEMWLILRLKLIADAGLVGLPNAGKSTFLATVT
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEEE
AAKPKIADYPFTTLHPGLGVVRSDEREFVLADIPGLIEGAHEGVGLGDRFLAHVERCRVL
CCCCCCCCCCCHHCCCCCCCEECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVEGTSEHAGKAYKLVRRELEAYGEGLSDKPEIVALSKADALDADTLKQQLARLKRAA
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHC
GGKPLVLSAASGQGVQEALRAIQAQLDTQGAEEAEAQPAEPWQP
CCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA