Definition Methylobacterium chloromethanicum CM4, complete genome.
Accession NC_011757
Length 5,777,908

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The map label for this gene is yohF [C]

Identifier: 218532730

GI number: 218532730

Start: 5162299

End: 5163042

Strand: Reverse

Name: yohF [C]

Synonym: Mchl_4852

Alternate gene names: 218532730

Gene position: 5163042-5162299 (Counterclockwise)

Preceding gene: 218532731

Following gene: 218532729

Centisome position: 89.36

GC content: 70.3

Gene sequence:

>744_bases
ATGAGGGATCGGGTGGCGGTCGTGACCGGGGCAGGCTCCGGCATCGGGCGAGCGGTGGCGCTGGGGTTGGCGCAGGCCGG
GTGGCGGCTGGTGCTGGCCGGGCGGCGGGGCGAGGCGCTGGAGCGGGTCGCGGCAGAACTGCCGGGCCCGTCTTTGTGCG
TGCCGACCGACGTGTCCGATCCGCGCGCCGTCGAGGCCCTGTTCGCCGCGGTGGGCGAGCGCTTCGGGCGGCTCGACCTG
CTGTTCAACAATGCCGGGATCTTCACCCCCGCCGCGACGGTGGACGAGATCGCGGTCGAGGATTGGCTCGCCAGCGTCAA
CGTCAACCTCACGGGCACCTTCCTCTGCACCCGCGCCGCCTTCGGGATGATGCGCAAGCAGGACCCCAGGGGAGGGCGCA
TCATCAACAACGGCTCGATCGCGGCCTATGCGCCACGGCCGATGTCGGCGCCCTACAGCGCGACCAAACATGCCATCACC
GGCCTCACCCGCACCACGGCCCTGGATGGACGCCCCTTCGACATCGCCTGCGGGCAGATCGATGTCGGCAATGCCGAGAC
CGAAATGACGCAAAGCTTCGGGAAGGGCGCGCGGCAGGCCGACGGCTCGATCCGGCCCGAGCCCTACATGGAGGCGGCCC
ATGTCGCGGAGGCCGTCGTCTACATGGCCGGGCTGCCGCTCTCGGCCAACGTGCTGTTCATGACCGTGATGGCGACGAAC
ATGCCCTTCGTCGGGCGAGGGTAG

Upstream 100 bases:

>100_bases
TCCCGCGATCGGCCGAGCAGGCGCGGCGCCCCTGCACCGGATCGATGCGACCGCTTATTCTAAGGCTCGACGGCAGGAGC
GGGACGGCAGAGGAATGGCG

Downstream 100 bases:

>100_bases
GGGAGTCGGCTTTGCGTAGGCGGCGCGGAACGCGTAGAGAGCGGAACACCGCCCGGTCCCCCTTCGAGACGAGCGGCCGA
CCGCCCCGCGGCGGCCGGTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRDRVAVVTGAGSGIGRAVALGLAQAGWRLVLAGRRGEALERVAAELPGPSLCVPTDVSDPRAVEALFAAVGERFGRLDL
LFNNAGIFTPAATVDEIAVEDWLASVNVNLTGTFLCTRAAFGMMRKQDPRGGRIINNGSIAAYAPRPMSAPYSATKHAIT
GLTRTTALDGRPFDIACGQIDVGNAETEMTQSFGKGARQADGSIRPEPYMEAAHVAEAVVYMAGLPLSANVLFMTVMATN
MPFVGRG

Sequences:

>Translated_247_residues
MRDRVAVVTGAGSGIGRAVALGLAQAGWRLVLAGRRGEALERVAAELPGPSLCVPTDVSDPRAVEALFAAVGERFGRLDL
LFNNAGIFTPAATVDEIAVEDWLASVNVNLTGTFLCTRAAFGMMRKQDPRGGRIINNGSIAAYAPRPMSAPYSATKHAIT
GLTRTTALDGRPFDIACGQIDVGNAETEMTQSFGKGARQADGSIRPEPYMEAAHVAEAVVYMAGLPLSANVLFMTVMATN
MPFVGRG
>Mature_247_residues
MRDRVAVVTGAGSGIGRAVALGLAQAGWRLVLAGRRGEALERVAAELPGPSLCVPTDVSDPRAVEALFAAVGERFGRLDL
LFNNAGIFTPAATVDEIAVEDWLASVNVNLTGTFLCTRAAFGMMRKQDPRGGRIINNGSIAAYAPRPMSAPYSATKHAIT
GLTRTTALDGRPFDIACGQIDVGNAETEMTQSFGKGARQADGSIRPEPYMEAAHVAEAVVYMAGLPLSANVLFMTVMATN
MPFVGRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=32.3404255319149, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI40254992, Length=231, Percent_Identity=31.1688311688312, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI31542939, Length=171, Percent_Identity=35.672514619883, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=35.2941176470588, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4504505, Length=231, Percent_Identity=32.4675324675325, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=178, Percent_Identity=31.4606741573034, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI7706318, Length=171, Percent_Identity=34.5029239766082, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI59889578, Length=174, Percent_Identity=31.6091954022989, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=234, Percent_Identity=31.6239316239316, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723191, Length=205, Percent_Identity=28.2926829268293, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=32.6530612244898, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI83715985, Length=184, Percent_Identity=33.695652173913, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=32.8125, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20149619, Length=213, Percent_Identity=31.924882629108, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19923817, Length=179, Percent_Identity=29.0502793296089, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI15277342, Length=235, Percent_Identity=31.063829787234, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503817, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI209862901, Length=201, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI19923983, Length=201, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=224, Percent_Identity=29.0178571428571, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=173, Percent_Identity=37.5722543352601, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=32.1428571428571, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367175, Length=226, Percent_Identity=31.858407079646, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789057, Length=197, Percent_Identity=34.010152284264, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=28.6290322580645, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787335, Length=221, Percent_Identity=28.5067873303167, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789208, Length=195, Percent_Identity=31.7948717948718, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082100, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=169, Percent_Identity=28.4023668639053, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790717, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=175, Percent_Identity=28, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=236, Percent_Identity=31.7796610169492, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=228, Percent_Identity=30.2631578947368, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=209, Percent_Identity=30.622009569378, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=191, Percent_Identity=34.5549738219895, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=177, Percent_Identity=31.0734463276836, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=31.1224489795918, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=243, Percent_Identity=29.2181069958848, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=25.2873563218391, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=181, Percent_Identity=29.8342541436464, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=25.7575757575758, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=209, Percent_Identity=27.7511961722488, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=176, Percent_Identity=31.25, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=181, Percent_Identity=31.4917127071823, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.4436090225564, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=225, Percent_Identity=29.7777777777778, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.1368821292776, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=176, Percent_Identity=28.9772727272727, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=171, Percent_Identity=29.2397660818713, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=177, Percent_Identity=29.3785310734463, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=201, Percent_Identity=32.3383084577114, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=227, Percent_Identity=29.0748898678414, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=178, Percent_Identity=31.4606741573034, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=32.2709163346614, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17737361, Length=233, Percent_Identity=33.0472103004292, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI116007238, Length=179, Percent_Identity=35.7541899441341, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI116007234, Length=255, Percent_Identity=31.3725490196078, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI23397609, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24580925, Length=186, Percent_Identity=33.8709677419355, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=34.3283582089552, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=29.3103448275862, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007232, Length=183, Percent_Identity=34.4262295081967, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571387, Length=253, Percent_Identity=29.6442687747036, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=223, Percent_Identity=26.9058295964126, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21355631, Length=226, Percent_Identity=27.8761061946903, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641388, Length=247, Percent_Identity=29.1497975708502, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648693, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355889, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=170, Percent_Identity=31.1764705882353, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641232, Length=172, Percent_Identity=33.7209302325581, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281364494, Length=253, Percent_Identity=28.8537549407115, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=32.9787234042553, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21358495, Length=223, Percent_Identity=28.6995515695067, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331218, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665243, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331216, Length=172, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24665247, Length=172, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25926; Mature: 25926

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRDRVAVVTGAGSGIGRAVALGLAQAGWRLVLAGRRGEALERVAAELPGPSLCVPTDVSD
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCC
PRAVEALFAAVGERFGRLDLLFNNAGIFTPAATVDEIAVEDWLASVNVNLTGTFLCTRAA
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHH
FGMMRKQDPRGGRIINNGSIAAYAPRPMSAPYSATKHAITGLTRTTALDGRPFDIACGQI
HHHHHCCCCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHCCHHHEECCCCCCEEECCEE
DVGNAETEMTQSFGKGARQADGSIRPEPYMEAAHVAEAVVYMAGLPLSANVLFMTVMATN
ECCCCHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHHC
MPFVGRG
CCCCCCC
>Mature Secondary Structure
MRDRVAVVTGAGSGIGRAVALGLAQAGWRLVLAGRRGEALERVAAELPGPSLCVPTDVSD
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCC
PRAVEALFAAVGERFGRLDLLFNNAGIFTPAATVDEIAVEDWLASVNVNLTGTFLCTRAA
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHH
FGMMRKQDPRGGRIINNGSIAAYAPRPMSAPYSATKHAITGLTRTTALDGRPFDIACGQI
HHHHHCCCCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHCCHHHEECCCCCCEEECCEE
DVGNAETEMTQSFGKGARQADGSIRPEPYMEAAHVAEAVVYMAGLPLSANVLFMTVMATN
ECCCCHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHHC
MPFVGRG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]