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The map label for this gene is yegE [C]

Identifier: 218532682

GI number: 218532682

Start: 5089351

End: 5091213

Strand: Reverse

Name: yegE [C]

Synonym: Mchl_4799

Alternate gene names: 218532682

Gene position: 5091213-5089351 (Counterclockwise)

Preceding gene: 218532684

Following gene: 218532681

Centisome position: 88.12

GC content: 62.32

Gene sequence:

>1863_bases
ATGGGCAGTCGCAACTCGCTCGATTGGCCGCCTGGCAGTAGTGAAATGGTGGAGCGCATCCGCGCGCATGACTGGTCAGG
ATCGCCGCTTGGATCAGCCGAGCACTGGTCACCACGCCTCAAACTTGCTGTCGAGATGGCGCTGGCCAACCCTCTTGCCA
CCAGCCTTATATGCGGGCCAGAACGCCTCCTCATCTACAACGATGCGGCTGCTACCTTTCTAGGCGAGCACCATCCCGCG
GCTCTCGGCCAAACACTGCCTCATACCTTCCCGGCTGGCTGGGCGGCGGCCGAGCCGTTCTACCAGCGTGCCTTCGCAGG
TGAGGTGATACAGGTCCACAGCCAAGCACTCAGTATGTGTTGTGAGGGTCAGGCGAACGCAGACGTGTCCGATGCCATCC
TCATGCCTGTGCGCGACGAGGACGGACAAGTCGCTTACGTCCATATGATCTGCACTGAGAATGGCGGGCGGGCTCGAGCC
GAAACCATCGCACGTCAGAGTGACGAGCAACTCGCCGCTATCTTCGGCAGCGCCGCAGTCGGGCTGTCCGAGATTGCGCA
GGATGGCCGCTTCCTACGTGCCAACGACGAGCTCTGCCGTATCCTGGGGCGCACCCGTGAGGAGGTGCTGCGTCTCACCG
TGATGGACGTGACGTATCCTGACGACGTCCCCCCCAGCCTGATCGCTGTCGCGGAGGCGCTTCGAACAAACCAGCCCGCC
TCGTTGGACAAACGCTATCTGCGCCCTGACGGTAATCACGTGTGGGCCAACAGCCGTGTGCAACCGCTGCACCATGAGGG
CGAGCCGAGTACGCTCTTGGCTGTCACGGCTGACTTGAGCGAGCGCCGTCACACCGAGGAGCGCCTGCGCGAGAGCGAGG
AGCGGTTCCGGGCGTTAGCGAACCTTGTGCCGGTCATTCTATGGCGCTCGGACGCAAGCGGGCTCACCTTCTCAGAGAAC
CAATCCTTCCTCGATTACACCGGCCAAACGGCAGACGAGGTGCAGGACTTCGGCTGGCTCGCCCCAATGCATCCCCATGA
CCGTAAGGGCGTGCAGGAGCCATTTGTGCATGGAATCGAGACCAAGCAGCCAATCGACGCGCAGTTTCGACTGCGTAGCC
GCGATGGACAATACCGGTGGTTCCTCGCACGGCAGGTGCCAATCTTTGGCGGAGAGGGGCAGGTAACGGAGTGGTTCGGC
GCGGCCATGGACATCCACGAGCTGCACGAGTTGCAGCAGCGACAAGCCGTCATGGTGGATGAACTGCAGCACCGCACCCG
CAACCTGCTCACTGTGGTGCGCGCCATCGCGCAGCAAACGATGGCTCAGACCGGCCCGACTGCGTTGTTCCGCGAGCACT
TCAACGACCGCCTTGCAGCACTCTCTCGCGTGCAGGGCCTGCTCTCCCGCTCTGACCAAGAGCCAATTACCATTCGGGCC
CTTGTCGAGATGGAGCTTGATGCGCTCGGAGCGACCGACATGGGCGAGCGCATCGCGGTAGAGGGGCCTCGGGTGGTGCT
GCGCAAGGGCAGTGTGCAGACGTTGGCTCTGGCTCTGCACGAACTTGCCACCAATGCGCGCAAGTACGGTGCCTTGTCCT
GTGAGCAGGCCGAACTCTGGGTCAGCTGGGACACCTACACCGCCGAAGCCGGAGAGCAGCGACTTGCGCTTACATGGCTG
GAGGAGGGAATCTGCCGTTCGCAACAGAGCAACCCGATCCGGCGGGGCTATGGGCGCGAGCTGATCGAGAAGGCGCTACC
CTACACGCTAAAGGCACATACAGACTATGAACTTGGCGAGAATGAGCTGCGTTGCTCCATTGACCTGCCACTCAATGAGC
TTGCAGGGGCAAGGGCCCAATGA

Upstream 100 bases:

>100_bases
TCTGAGCGACCCGAATTCAGAGCAAATCGCTTTACTGACGGCCGATCAACGCGCTCGGATTCGTGGTAAGATCGGGGCCA
GGGCATGTAGGAGAGGCCCC

Downstream 100 bases:

>100_bases
CCTCTGCAGCGAACCATTGGGTGGGATGCCGTGTACTCCTAGTGGAGGATGATTACCTCATCGCAAATGCTATGGATGCC
GAGTTCGAAGCACTCGGGGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MGSRNSLDWPPGSSEMVERIRAHDWSGSPLGSAEHWSPRLKLAVEMALANPLATSLICGPERLLIYNDAAATFLGEHHPA
ALGQTLPHTFPAGWAAAEPFYQRAFAGEVIQVHSQALSMCCEGQANADVSDAILMPVRDEDGQVAYVHMICTENGGRARA
ETIARQSDEQLAAIFGSAAVGLSEIAQDGRFLRANDELCRILGRTREEVLRLTVMDVTYPDDVPPSLIAVAEALRTNQPA
SLDKRYLRPDGNHVWANSRVQPLHHEGEPSTLLAVTADLSERRHTEERLRESEERFRALANLVPVILWRSDASGLTFSEN
QSFLDYTGQTADEVQDFGWLAPMHPHDRKGVQEPFVHGIETKQPIDAQFRLRSRDGQYRWFLARQVPIFGGEGQVTEWFG
AAMDIHELHELQQRQAVMVDELQHRTRNLLTVVRAIAQQTMAQTGPTALFREHFNDRLAALSRVQGLLSRSDQEPITIRA
LVEMELDALGATDMGERIAVEGPRVVLRKGSVQTLALALHELATNARKYGALSCEQAELWVSWDTYTAEAGEQRLALTWL
EEGICRSQQSNPIRRGYGRELIEKALPYTLKAHTDYELGENELRCSIDLPLNELAGARAQ

Sequences:

>Translated_620_residues
MGSRNSLDWPPGSSEMVERIRAHDWSGSPLGSAEHWSPRLKLAVEMALANPLATSLICGPERLLIYNDAAATFLGEHHPA
ALGQTLPHTFPAGWAAAEPFYQRAFAGEVIQVHSQALSMCCEGQANADVSDAILMPVRDEDGQVAYVHMICTENGGRARA
ETIARQSDEQLAAIFGSAAVGLSEIAQDGRFLRANDELCRILGRTREEVLRLTVMDVTYPDDVPPSLIAVAEALRTNQPA
SLDKRYLRPDGNHVWANSRVQPLHHEGEPSTLLAVTADLSERRHTEERLRESEERFRALANLVPVILWRSDASGLTFSEN
QSFLDYTGQTADEVQDFGWLAPMHPHDRKGVQEPFVHGIETKQPIDAQFRLRSRDGQYRWFLARQVPIFGGEGQVTEWFG
AAMDIHELHELQQRQAVMVDELQHRTRNLLTVVRAIAQQTMAQTGPTALFREHFNDRLAALSRVQGLLSRSDQEPITIRA
LVEMELDALGATDMGERIAVEGPRVVLRKGSVQTLALALHELATNARKYGALSCEQAELWVSWDTYTAEAGEQRLALTWL
EEGICRSQQSNPIRRGYGRELIEKALPYTLKAHTDYELGENELRCSIDLPLNELAGARAQ
>Mature_619_residues
GSRNSLDWPPGSSEMVERIRAHDWSGSPLGSAEHWSPRLKLAVEMALANPLATSLICGPERLLIYNDAAATFLGEHHPAA
LGQTLPHTFPAGWAAAEPFYQRAFAGEVIQVHSQALSMCCEGQANADVSDAILMPVRDEDGQVAYVHMICTENGGRARAE
TIARQSDEQLAAIFGSAAVGLSEIAQDGRFLRANDELCRILGRTREEVLRLTVMDVTYPDDVPPSLIAVAEALRTNQPAS
LDKRYLRPDGNHVWANSRVQPLHHEGEPSTLLAVTADLSERRHTEERLRESEERFRALANLVPVILWRSDASGLTFSENQ
SFLDYTGQTADEVQDFGWLAPMHPHDRKGVQEPFVHGIETKQPIDAQFRLRSRDGQYRWFLARQVPIFGGEGQVTEWFGA
AMDIHELHELQQRQAVMVDELQHRTRNLLTVVRAIAQQTMAQTGPTALFREHFNDRLAALSRVQGLLSRSDQEPITIRAL
VEMELDALGATDMGERIAVEGPRVVLRKGSVQTLALALHELATNARKYGALSCEQAELWVSWDTYTAEAGEQRLALTWLE
EGICRSQQSNPIRRGYGRELIEKALPYTLKAHTDYELGENELRCSIDLPLNELAGARAQ

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=240, Percent_Identity=26.25, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69074; Mature: 68942

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRNSLDWPPGSSEMVERIRAHDWSGSPLGSAEHWSPRLKLAVEMALANPLATSLICGP
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCC
ERLLIYNDAAATFLGEHHPAALGQTLPHTFPAGWAAAEPFYQRAFAGEVIQVHSQALSMC
CEEEEECCHHHHHHCCCCCHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
CEGQANADVSDAILMPVRDEDGQVAYVHMICTENGGRARAETIARQSDEQLAAIFGSAAV
HCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
GLSEIAQDGRFLRANDELCRILGRTREEVLRLTVMDVTYPDDVPPSLIAVAEALRTNQPA
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHEEHEEEECCCCCCCHHHHHHHHHHHCCCCC
SLDKRYLRPDGNHVWANSRVQPLHHEGEPSTLLAVTADLSERRHTEERLRESEERFRALA
CHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
NLVPVILWRSDASGLTFSENQSFLDYTGQTADEVQDFGWLAPMHPHDRKGVQEPFVHGIE
HHHHEEEECCCCCCCEECCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC
TKQPIDAQFRLRSRDGQYRWFLARQVPIFGGEGQVTEWFGAAMDIHELHELQQRQAVMVD
CCCCCCHHEEEECCCCCEEEEEEEECCEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
ELQHRTRNLLTVVRAIAQQTMAQTGPTALFREHFNDRLAALSRVQGLLSRSDQEPITIRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LVEMELDALGATDMGERIAVEGPRVVLRKGSVQTLALALHELATNARKYGALSCEQAELW
EEEHHHHHCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VSWDTYTAEAGEQRLALTWLEEGICRSQQSNPIRRGYGRELIEKALPYTLKAHTDYELGE
EEECCEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
NELRCSIDLPLNELAGARAQ
CCEEEEECCCHHHHCCCCCC
>Mature Secondary Structure 
GSRNSLDWPPGSSEMVERIRAHDWSGSPLGSAEHWSPRLKLAVEMALANPLATSLICGP
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCC
ERLLIYNDAAATFLGEHHPAALGQTLPHTFPAGWAAAEPFYQRAFAGEVIQVHSQALSMC
CEEEEECCHHHHHHCCCCCHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHH
CEGQANADVSDAILMPVRDEDGQVAYVHMICTENGGRARAETIARQSDEQLAAIFGSAAV
HCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
GLSEIAQDGRFLRANDELCRILGRTREEVLRLTVMDVTYPDDVPPSLIAVAEALRTNQPA
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHEEHEEEECCCCCCCHHHHHHHHHHHCCCCC
SLDKRYLRPDGNHVWANSRVQPLHHEGEPSTLLAVTADLSERRHTEERLRESEERFRALA
CHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
NLVPVILWRSDASGLTFSENQSFLDYTGQTADEVQDFGWLAPMHPHDRKGVQEPFVHGIE
HHHHEEEECCCCCCCEECCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC
TKQPIDAQFRLRSRDGQYRWFLARQVPIFGGEGQVTEWFGAAMDIHELHELQQRQAVMVD
CCCCCCHHEEEECCCCCEEEEEEEECCEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
ELQHRTRNLLTVVRAIAQQTMAQTGPTALFREHFNDRLAALSRVQGLLSRSDQEPITIRA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LVEMELDALGATDMGERIAVEGPRVVLRKGSVQTLALALHELATNARKYGALSCEQAELW
EEEHHHHHCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VSWDTYTAEAGEQRLALTWLEEGICRSQQSNPIRRGYGRELIEKALPYTLKAHTDYELGE
EEECCEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
NELRCSIDLPLNELAGARAQ
CCEEEEECCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA