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The map label for this gene is atoS [C]

Identifier: 218532673

GI number: 218532673

Start: 5074765

End: 5076822

Strand: Reverse

Name: atoS [C]

Synonym: Mchl_4788

Alternate gene names: 218532673

Gene position: 5076822-5074765 (Counterclockwise)

Preceding gene: 218532674

Following gene: 218532671

Centisome position: 87.87

GC content: 69.97

Gene sequence:

>2058_bases
GTGCGCCGAGGTCTCGTCCTGCTCACCCTCGCAGCCCTGCTGCCGCTGGTGCTGCTCTCCGGGGCACTGTCGTTTCTGCT
CCTGCACCAGGAGCAGGCCACGATGCGCTCAGAGGCGGTGCACCAGGTCGAGCGGATGCTCGGCAGCGTCGACCGGGAAC
TCTATACCCAGATCGAGCTCCTCAAGGTTCTGGCCCAATCGCCGATACTCGACGGCAACCAGCCGAGTCTGGCTGCCTTC
CACGACCTGGCCGAGCGCTTCCAGAGCCAGCTTCCACTCTGGCACCGTATCATCCTCGCCGACGCCGAGGGCCACATGCT
GGTGCGAACGGGTGCCTCCTTCGGCACCCCGCTCCCGCCCCTCGTCGACGAGAGGAGCTACAGGCGGGTGCTCGACACGG
GTGAGCCTACCATCGGCGACGTCGCGGCCTCGGCCTCCAGCAGCGATCCGCCGCGGGCGAGCTTCCGCGTGCCCGTCCGG
CGCGACGGCGCGATCCGCTACGTGCTGACGGGCGTGGTCTCCACCAAGCGCCTGACCGAGCTCCTCGCAACGACCGGCCT
CGATCCCGCTTGGCGGCCCTACCTCGTCGACGGCTCCGGCCGCATCGCCGCTAGCCTACGCCGGCCCGACACCGTGGGTC
GGCAAGCGATGGCGCCGACCGTCCGCGCCCGGGAAGGCGGCGCGTCGGGCGTCTACGACGGCATCTCGCCGGAAGGCGAG
CTGCTGGTCACCGCCTTCCGCAAGTCGGACAGGACCGGATGGTCGGTGCACGTCGCCATCCCGCTGGGCGTCTACAACCA
GCCGCTGACGCGGGCCGCCTGGGTCCTGGCCTGCGCCGGGGCCGCCGCGGTCCTGTTGACGGCAGCCTTCATCCTCCTGC
TCCGGCGCGAGCTCCGGGCGCAGCGCCGGGAGGCGCTCACCCATGAGCGGGCGGTGCGCATGGAAGCCCTCGGGCGCATG
ACCGGCGGTGTCGCGCACGACTTCAACAACCTGCTTATGGTCATCCTGGGCAATCTGGAGATGCTCGGGCGGCGCAACCA
GGAGCCGCGCCTGGAGCGCTACGTCACAGCCATCCGCAAGGCGGCCGAGCGCGGCACACACCTCACCCGCGAGCTGCTCG
CCTTTTCGCGGGGCCAGGCCAGCCAGTCCGAGGTCGTCGATCTCAATGAGCGGTTGGCCAGTACGCTCACCATGATCCGG
CAATCCGTCAGCGGCCACATCCACGTCGAGACCGACCTCGTCCCCGGGCGGCACGCCGTCAGGCTCGACCCGCTGCAGTT
CGACCTCGCGCTGCTCAACATCGCCGCCAACGCCCGCGACGCCATGCCGGAGGGCGGCAGCCTGCGGATCGCGACCCGCC
GGGCCCTGCTGCCGGGCCGGTCCGGGCGCGAAGGGATCGCGTTGTCCATCAAGGACACGGGCGGCGGCATCCCGCCGGAA
GCCCTGCCGCACGTGTTCGAGCCGTTCTTCACGACCAAGGACGTTGGGAAGGGGACCGGCCTCGGCCTGAGCCAGGTCTT
CGGCTTCGCCAAGCAGTCGGGCGGCGCGGCCGACATCGAGAGCCGGTCAGGACAGGGCACGACCGTCACCCTGCACTTGC
CGCTGGCGCAGGAAGAGGTACCGGCAGCGAGGATGCTTGCGGACGCAGATGGAGCCTCGCCAAGCTCGACCGCGGCCCGG
GTGGTCCTGATCGATGACAACGACGAGGTGCGCACCGTGACGGCCTCCTTCCTGGAGGATGCTGGCTTCCGGGTCGAGCA
AGCCAACTCTGCGCAGGCCGGGTTGGACCTGCTTGAGCGAAGTGGTGCCGACATCCTGGTGAGCGACTTGGTCATGCCCG
GCGGCATGGACGGGCTGGCGTTTGCCAACGAGGCGCGCCGGCGCTGGCCGCACCTGCCGGTGATCCTGGTGTCGGGCTAC
AGCACCTCGGCGGCGCGGGCGACTGAGCTTGGCTACTCGCTCTACATGAAGCCGTTCGACATGGCCGAGCTCGCCAAGGG
CATCCGGGCTCAGCTAGGCCCGAGAGACCGACAGTTGGCGGTGCCGGGACCTAGTTGA

Upstream 100 bases:

>100_bases
CCGGGTCGCACCTCGATTGTGTCAGAAAACGTCGGCTTGAATGGAAAGCTAGGCTTTTTGCACTAGGTCTGGTTCAGCCG
AACCATGGGGATCGACGAGG

Downstream 100 bases:

>100_bases
CCGCTGCGACGGGAGCAAGCCGGGATAGCCCGACCCGAGGCCACACGCTACTCCCTGCCACTTCAGCCTTGTCCCTCGCC
GTCCTCAGCCGGCCTGCGGC

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MRRGLVLLTLAALLPLVLLSGALSFLLLHQEQATMRSEAVHQVERMLGSVDRELYTQIELLKVLAQSPILDGNQPSLAAF
HDLAERFQSQLPLWHRIILADAEGHMLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSDPPRASFRVPVR
RDGAIRYVLTGVVSTKRLTELLATTGLDPAWRPYLVDGSGRIAASLRRPDTVGRQAMAPTVRAREGGASGVYDGISPEGE
LLVTAFRKSDRTGWSVHVAIPLGVYNQPLTRAAWVLACAGAAAVLLTAAFILLLRRELRAQRREALTHERAVRMEALGRM
TGGVAHDFNNLLMVILGNLEMLGRRNQEPRLERYVTAIRKAAERGTHLTRELLAFSRGQASQSEVVDLNERLASTLTMIR
QSVSGHIHVETDLVPGRHAVRLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPGRSGREGIALSIKDTGGGIPPE
ALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIESRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAAR
VVLIDDNDEVRTVTASFLEDAGFRVEQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGY
STSAARATELGYSLYMKPFDMAELAKGIRAQLGPRDRQLAVPGPS

Sequences:

>Translated_685_residues
MRRGLVLLTLAALLPLVLLSGALSFLLLHQEQATMRSEAVHQVERMLGSVDRELYTQIELLKVLAQSPILDGNQPSLAAF
HDLAERFQSQLPLWHRIILADAEGHMLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSDPPRASFRVPVR
RDGAIRYVLTGVVSTKRLTELLATTGLDPAWRPYLVDGSGRIAASLRRPDTVGRQAMAPTVRAREGGASGVYDGISPEGE
LLVTAFRKSDRTGWSVHVAIPLGVYNQPLTRAAWVLACAGAAAVLLTAAFILLLRRELRAQRREALTHERAVRMEALGRM
TGGVAHDFNNLLMVILGNLEMLGRRNQEPRLERYVTAIRKAAERGTHLTRELLAFSRGQASQSEVVDLNERLASTLTMIR
QSVSGHIHVETDLVPGRHAVRLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPGRSGREGIALSIKDTGGGIPPE
ALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIESRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAAR
VVLIDDNDEVRTVTASFLEDAGFRVEQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGY
STSAARATELGYSLYMKPFDMAELAKGIRAQLGPRDRQLAVPGPS
>Mature_685_residues
MRRGLVLLTLAALLPLVLLSGALSFLLLHQEQATMRSEAVHQVERMLGSVDRELYTQIELLKVLAQSPILDGNQPSLAAF
HDLAERFQSQLPLWHRIILADAEGHMLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSDPPRASFRVPVR
RDGAIRYVLTGVVSTKRLTELLATTGLDPAWRPYLVDGSGRIAASLRRPDTVGRQAMAPTVRAREGGASGVYDGISPEGE
LLVTAFRKSDRTGWSVHVAIPLGVYNQPLTRAAWVLACAGAAAVLLTAAFILLLRRELRAQRREALTHERAVRMEALGRM
TGGVAHDFNNLLMVILGNLEMLGRRNQEPRLERYVTAIRKAAERGTHLTRELLAFSRGQASQSEVVDLNERLASTLTMIR
QSVSGHIHVETDLVPGRHAVRLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPGRSGREGIALSIKDTGGGIPPE
ALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIESRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAAR
VVLIDDNDEVRTVTASFLEDAGFRVEQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGY
STSAARATELGYSLYMKPFDMAELAKGIRAQLGPRDRQLAVPGPS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=29.2592592592593, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790300, Length=283, Percent_Identity=28.9752650176678, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=29.9107142857143, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=280, Percent_Identity=24.2857142857143, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI145693157, Length=317, Percent_Identity=23.0283911671924, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=365, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73812; Mature: 73812

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGLVLLTLAALLPLVLLSGALSFLLLHQEQATMRSEAVHQVERMLGSVDRELYTQIEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVLAQSPILDGNQPSLAAFHDLAERFQSQLPLWHRIILADAEGHMLVRTGASFGTPLPP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCCC
LVDERSYRRVLDTGEPTIGDVAASASSSDPPRASFRVPVRRDGAIRYVLTGVVSTKRLTE
CCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHH
LLATTGLDPAWRPYLVDGSGRIAASLRRPDTVGRQAMAPTVRAREGGASGVYDGISPEGE
HHHHCCCCCCCCCEEECCCCCEEEECCCCCHHCHHHHCCCHHCCCCCCCCCCCCCCCCCC
LLVTAFRKSDRTGWSVHVAIPLGVYNQPLTRAAWVLACAGAAAVLLTAAFILLLRRELRA
EEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRREALTHERAVRMEALGRMTGGVAHDFNNLLMVILGNLEMLGRRNQEPRLERYVTAIRK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHH
AAERGTHLTRELLAFSRGQASQSEVVDLNERLASTLTMIRQSVSGHIHVETDLVPGRHAV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
RLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPGRSGREGIALSIKDTGGGIPPE
EECCHHHHHHHHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCCCCEEEEEECCCCCCCHH
ALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIESRSGQGTTVTLHLPLAQEEV
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHC
PAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRVEQANSAQAGLDLLER
CHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
SGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSAARATELGYSLYMKPFD
CCCCEEHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCHHEECCCCC
MAELAKGIRAQLGPRDRQLAVPGPS
HHHHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MRRGLVLLTLAALLPLVLLSGALSFLLLHQEQATMRSEAVHQVERMLGSVDRELYTQIEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVLAQSPILDGNQPSLAAFHDLAERFQSQLPLWHRIILADAEGHMLVRTGASFGTPLPP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCCC
LVDERSYRRVLDTGEPTIGDVAASASSSDPPRASFRVPVRRDGAIRYVLTGVVSTKRLTE
CCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHH
LLATTGLDPAWRPYLVDGSGRIAASLRRPDTVGRQAMAPTVRAREGGASGVYDGISPEGE
HHHHCCCCCCCCCEEECCCCCEEEECCCCCHHCHHHHCCCHHCCCCCCCCCCCCCCCCCC
LLVTAFRKSDRTGWSVHVAIPLGVYNQPLTRAAWVLACAGAAAVLLTAAFILLLRRELRA
EEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRREALTHERAVRMEALGRMTGGVAHDFNNLLMVILGNLEMLGRRNQEPRLERYVTAIRK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHH
AAERGTHLTRELLAFSRGQASQSEVVDLNERLASTLTMIRQSVSGHIHVETDLVPGRHAV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
RLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPGRSGREGIALSIKDTGGGIPPE
EECCHHHHHHHHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCCCCEEEEEECCCCCCCHH
ALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIESRSGQGTTVTLHLPLAQEEV
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHC
PAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRVEQANSAQAGLDLLER
CHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
SGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSAARATELGYSLYMKPFD
CCCCEEHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCHHEECCCCC
MAELAKGIRAQLGPRDRQLAVPGPS
HHHHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA