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The map label for this gene is yfnA [H]

Identifier: 218235871

GI number: 218235871

Start: 838750

End: 840153

Strand: Reverse

Name: yfnA [H]

Synonym: BCB4264_A0872

Alternate gene names: 218235871

Gene position: 840153-838750 (Counterclockwise)

Preceding gene: 218232824

Following gene: 218231700

Centisome position: 15.5

GC content: 39.89

Gene sequence:

>1404_bases
GTGAAGTCATTATTACGAAAAAAAGCGCTTAGTACTGAATCACCAAAGCAGCTAGCTAGAACATTAACTGCACTCGATTT
AACATTTTTAGGAATCGGCGCCGTAATTGGGACAGGGATCTTTGTATTAACAGGTATTGTTGCAGCAAAACATTCTGGTC
CTGGTATTATGCTATCATTCCTTATTGCTGCATTTACTTGTGCTTGTGTAGCCTTTTGTTACGCTGAATTTGCTTCTTCT
ATTCCTGTCTCAGGAAGTGTGTATACTTACGCATACATGACAGTCGGAGAAGTCGTCGCCTTCATCGTCGGATGGTGTTT
AATGCTCGAATATTTACTTGCCGTTGCAGCAGTAGCTGTCGGTTGGTCTGGTTATTTGCAATCATTACTACAAGGGTTCA
ATATACACCTGCCCGCCATAATCGCCTCGGCCCCCGGCGTAGGAAAAGGTGGTCTCATCGATTTACCTGCTGTCTGTATT
TTACTTCTTATTACTGGCCTTTTAAGTTTTGGTATACGTGAAAGTGCACGCATTAATAATATTATGGTTCTTATTAAACT
AGCTGTTATCATTGCCTTTATCGTAGCAGGTGCAAAATATGTAAAACCTGAAAACTGGACACCGTTCATCCCATTCGGAT
ACGACGGTATTATTACTGGGGCTGCCACTGTGTTCTTCGCCTTCTTAGGATTTGATGCAATCGCAACAGCTGCAGAAGAA
ACGAAAAAACCGCAGCGTGACTTACCAATTGGTATTATCGGTTCTCTTCTTATTTGTACTGTTTTATATATGATCGTATC
TTTCGTTTTAACAGGTATGGTTCCTTATACGCAATTAGACGTTTCTGATCCAGTTGCATTTGCATTGCATTTCGTTGGTG
AGGATACAATTGCAGGACTACTCGCTGTTGGAGCGATGACTGGAATGACAACCGTTCTCTTAGTCGTTATGTATGGACAA
GTTCGCGTTTCGTATGCGATGAGCCGTGACGGTTTACTTCCAAAAGCGTTAGCACGTGTAAATAAAAAAGTAAAAATCCC
TTTATTAAATACGTGGATTACTGGCGTTGTTGCTGCTTTATTAGCAGGCCTTTTAGACTTACATTTGCTAGCGAATTTAG
TAAACATCGGCACGTTAACAGCCTTTACATTCGTTTGCTGCGCAGTACTTATTTTACGAAAAACACACCCTGATTTAAAA
CGTGGATTCCGTACACCTTTCGTACCTGTATTACCAGTTGTCGCGATTCTTTGCTGCTTATATTTAATGATCAATTTGTC
TAAAACAACATGGATTAGCTTTGCAGTTTGGCTTATAGTCGGCTTATGCTTCTATTTCTTCTACTCTAGGAAACATAGTC
ATTTAGCTATTGAAAAAACAAATGATGAAAAGAAAAAAGCATAA

Upstream 100 bases:

>100_bases
CATACCATAACTGCACCTCCACTTCCTTACTTACTCTTTTTTAATGGGCTCATACTATAGTCGCAGTTATGGAAATGAAA
AAACGGGGGGAGAGTCCAAA

Downstream 100 bases:

>100_bases
CAAAATAGCTCGCCGTTTTAGCGGCGAGCTATCTTTCTGTACTATTATATTTTTTCGTCAACGATTGTAAAATGAAAAAT
ATGCCGATGCAAGCTGTAAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKSLLRKKALSTESPKQLARTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLLITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKKVKIPLLNTWITGVVAALLAGLLDLHLLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLAIEKTNDEKKKA

Sequences:

>Translated_467_residues
MKSLLRKKALSTESPKQLARTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLLITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKKVKIPLLNTWITGVVAALLAGLLDLHLLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLAIEKTNDEKKKA
>Mature_467_residues
MKSLLRKKALSTESPKQLARTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLLITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKKVKIPLLNTWITGVVAALLAGLLDLHLLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLAIEKTNDEKKKA

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=40.2352941176471, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=40.2352941176471, Blast_Score=285, Evalue=7e-77,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=39.7647058823529, Blast_Score=278, Evalue=9e-75,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=38.4439359267735, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI114326544, Length=434, Percent_Identity=38.2488479262673, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI114326550, Length=434, Percent_Identity=38.2488479262673, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI181337167, Length=409, Percent_Identity=38.6308068459658, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI110347453, Length=401, Percent_Identity=38.4039900249377, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI186910308, Length=470, Percent_Identity=25.1063829787234, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910306, Length=470, Percent_Identity=25.1063829787234, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910304, Length=470, Percent_Identity=25.1063829787234, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71979932, Length=461, Percent_Identity=25.5965292841649, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI187423910, Length=475, Percent_Identity=22.7368421052632, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7657591, Length=475, Percent_Identity=22.7368421052632, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648063, Length=428, Percent_Identity=24.0654205607477, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI115648022, Length=428, Percent_Identity=24.0654205607477, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7657683, Length=355, Percent_Identity=25.3521126760563, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI33286428, Length=413, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082023, Length=454, Percent_Identity=26.8722466960352, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87081708, Length=491, Percent_Identity=23.4215885947047, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081869, Length=459, Percent_Identity=27.4509803921569, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788480, Length=453, Percent_Identity=26.7108167770419, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786302, Length=433, Percent_Identity=23.094688221709, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789017, Length=352, Percent_Identity=22.1590909090909, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786602, Length=481, Percent_Identity=23.4927234927235, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786789, Length=441, Percent_Identity=22.9024943310658, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790653, Length=414, Percent_Identity=21.9806763285024, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082250, Length=471, Percent_Identity=25.9023354564756, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367353, Length=461, Percent_Identity=22.3427331887202, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081915, Length=427, Percent_Identity=20.6088992974239, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994972, Length=343, Percent_Identity=23.6151603498542, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786908, Length=334, Percent_Identity=24.5508982035928, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=406, Percent_Identity=36.9458128078818, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17531343, Length=417, Percent_Identity=37.8896882494005, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17533459, Length=407, Percent_Identity=38.5749385749386, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17540018, Length=449, Percent_Identity=25.3897550111359, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982612, Length=414, Percent_Identity=23.4299516908213, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=414, Percent_Identity=23.4299516908213, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=431, Percent_Identity=23.4338747099768, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=431, Percent_Identity=23.4338747099768, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=435, Percent_Identity=23.6781609195402, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=395, Percent_Identity=22.2784810126582, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=347, Percent_Identity=23.6311239193084, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319991, Length=343, Percent_Identity=25.0728862973761, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24668806, Length=417, Percent_Identity=39.8081534772182, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI21356285, Length=417, Percent_Identity=39.8081534772182, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24668802, Length=417, Percent_Identity=39.8081534772182, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI221512776, Length=418, Percent_Identity=38.0382775119617, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24666159, Length=418, Percent_Identity=38.0382775119617, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24667468, Length=425, Percent_Identity=37.8823529411765, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI161077963, Length=393, Percent_Identity=37.9134860050891, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=36.3414634146341, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=36.3414634146341, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI116007818, Length=410, Percent_Identity=36.3414634146341, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI85725152, Length=410, Percent_Identity=36.3414634146341, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI21357367, Length=440, Percent_Identity=20.9090909090909, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221331183, Length=424, Percent_Identity=25.7075471698113, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647653, Length=424, Percent_Identity=25.7075471698113, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664379, Length=424, Percent_Identity=25.7075471698113, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651635, Length=404, Percent_Identity=24.2574257425743, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651633, Length=404, Percent_Identity=24.2574257425743, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550968, Length=466, Percent_Identity=22.9613733905579, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19921172, Length=466, Percent_Identity=22.9613733905579, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50149; Mature: 50149

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
>Mature Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]