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The map label for this gene is helD [H]

Identifier: 218235222

GI number: 218235222

Start: 1048278

End: 1050611

Strand: Reverse

Name: helD [H]

Synonym: BCB4264_A1075

Alternate gene names: 218235222

Gene position: 1050611-1048278 (Counterclockwise)

Preceding gene: 218233989

Following gene: 218231030

Centisome position: 19.39

GC content: 39.55

Gene sequence:

>2334_bases
ATGAACAAAAAACTTGATTTAGAGCAAAAAAGATTGGATACCGTAATCGAGACAATTACGGAGCAAATTGATAAACTGAA
AAACGAAACTGGCAGACGCCGGGCAGAAGTAATCAATATTCGTAAACACTTTTGGGATGATGTGAAAGTGAACACGGATA
CTTTTGATGATTATCTTGAAACAGTTATCAACTTAAGACAACAAGCTCAGTCACTAGCTGTCACACAAATTACCCATAAG
CATACCTTTAATCGACTTGCCGCATTAAGACGCATGCATAAAGCACCTTATTTTGGACGAATTGATTTCAAAGAAGAAGG
AGAATCTGCTGCGGATCAAATTTATATCGGTGTTGCTACACTTACGGATGCTAGCGGAGAAAACTTTCTTATATATGACT
GGCGCGCACCTATTTCGAGTGTATACTACGATTATCCACCAGGACCAGCTGAATACAGTACTCCAGGAGGCGTAATCCAC
GGTAATGTGGAGAAAAAATTACAATACATTATTCAAAATGGCGAGATTGATTCTATGTTCGATACGAGCCTTACAATTGG
CGATGAAATCTTGCAACAAGCGCTCGGAAAAGGTACGAACAAACATATGCAAAGTATCGTCGCTACAATTCAGCGTGAAC
AAAATGAAATTATTCGTCACGATGAAGGCCGACTCCTTATCGTGCAAGGAGCTGCTGGTAGTGGTAAAACGTCAGCTGCC
CTGCAGCGAATCGCCTACTTACTATATAAATATCGCGAATGGCTAAAAGCGGATCAAATTATTCTCTTCTCCCCTAACTC
TATGTTCAATAGCTACGTTTCTAACGTACTACCTGAACTCGGTGAAGAAAATATGCAGCAAGTGACATTCCAAGAATATT
TAAATCATAGACTGAGTAAGTCATTTGATGTTGAAGACCCTTATGAGCAATTGGAATATATGTTAACTGAAACGAATAGC
CCTACCTATAAAACGAGAAATGCGAGCATCCGATTTAAAGCATCCACTCAATTTTTCGAGATGATTAGAGCGTACAGACA
ATCTCTTGAATCTTCAGGCATGCTATTTAGAGGAATGAAATTTAGAGGAAAACTGATTGCCTCAGCTAAAGAAATTACAG
AGCAATTTTACAATACAGACTCCTCCCTCCGTTTCAATAATAGAATTGAAAAGTTAACGGATTGGCTAAATAAGCAAATA
GATGCACTTGAAAAAGCAGAACTGAAAAAGCCTTGGGTAGAAGAAGAAATTGAACTACTTAGTAAAGATGAATATCAAAA
GGCTTATAAATATTTACAGAAAAAAGGCGAGTTTGACGACAACTCCTTTAACGATTTTGAGAAAGAGGCGAAAGTACTTG
GACGTATGATTGTCCGTAAAAAATTGAAGCCTCTTCGTAAAGGCGTTCAAACATTGCGCTTTATCAATTTTACAGGTATA
TATAAACAGCTTTTCACAGATGCATCATGGGTTACTGGAGAAAAACCGAAAGAGTGGGATGATATTTGCTCATTAACAGT
AAATATGCTTGATGAAGGAAAGCTATATTACGAGGATGCGACTCCATTTTTACTTTTAAAAGAATTAATTGAAGGCTTCC
AAACGAACAGATCGATTAAACACGTACTCGTAGACGAAGCACAGGATTACTCGCCGTTTCAGTTCGAGTTTTTAAAACGT
CTCTTCCCTGCTGCAAGAATGACGGTACTCGGAGACTTTAACCAAGCGATATTTGCCCATGCGAGTGAAACGGTGAATTT
CGATACACTTACGAATTTATACGGGCCAGACGAAACAAACGGCATTAACTTAACTCGTAGCTATCGCTCAACAAAACCGA
TTATTGAATTTACACGTGCTCTCGTACCGGAAGGGAAGAACATTCACGCCTTTGAACGTGACGGCGAGAAACCTACAGTG
ACGAAAGTATCAAATGAAAGCGAACTGCACGAACATATTACTGCCAAAGTTGCTGAACTACAAAAAGAGCAGCACAATAC
GATCGCAATTATATGTAAATCTGCAGCTGAGAGCGCCGCTGCCTACGAAGCACTTAATCATATCGAGAATATTAAACTTG
TGAAAAGTAACTCAGCCGAGTATGAGCAAGGCATTGTCGTGATCCCCGCTTACTTAGCGAAAGGTATCGAATTTGATGCT
GTTATTATTTACGATGCTTCTAAAGATGTGTACAGCGATGAGAGCGTTCGTAGATTGTTCTACACTGCTTGTACGCGCGC
AATGCATGAATTGCACCTTTATAGCGTTGGCGAGGTTAGTCCTTTTGTGCTTGGGGCTGATTCGGAGAGTTTTGAGCTTA
TTACAACACCTTGA

Upstream 100 bases:

>100_bases
TTCTAAAATGAAAGGAACGTATTTATCCGTATTTTAATTGTACACCAAAACACATCTTCAGTCAACCTCTATTTTTCACT
TTTAAAGGAGTGCTTACCGT

Downstream 100 bases:

>100_bases
TAACAATCAAGGTGTTTTCTTTTTTATGCAGGACTTACACCTTTAAAGTAGAATATATGAGTTTAGAAAAAAGTTAAGGA
GTGAAAAGATGAACCATTAT

Product: helicase, UvrD/Rep family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MNKKLDLEQKRLDTVIETITEQIDKLKNETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAADQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIASAKEITEQFYNTDSSLRFNNRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVSNESELHEHITAKVAELQKEQHNTIAIICKSAAESAAAYEALNHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELHLYSVGEVSPFVLGADSESFELITTP

Sequences:

>Translated_777_residues
MNKKLDLEQKRLDTVIETITEQIDKLKNETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAADQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIASAKEITEQFYNTDSSLRFNNRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVSNESELHEHITAKVAELQKEQHNTIAIICKSAAESAAAYEALNHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELHLYSVGEVSPFVLGADSESFELITTP
>Mature_777_residues
MNKKLDLEQKRLDTVIETITEQIDKLKNETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAADQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIASAKEITEQFYNTDSSLRFNNRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVSNESELHEHITAKVAELQKEQHNTIAIICKSAAESAAAYEALNHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELHLYSVGEVSPFVLGADSESFELITTP

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 89284; Mature: 89284

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLDLEQKRLDTVIETITEQIDKLKNETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAADQIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECHH
FRGKLIASAKEITEQFYNTDSSLRFNNRIEKLTDWLNKQIDALEKAELKKPWVEEEIELL
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWVTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVSNESELHEHITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
QKEQHNTIAIICKSAAESAAAYEALNHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHHCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYSDESVRRLFYTACTRAMHELHLYSVGEVSPFVLGADSESFELITTP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECC
>Mature Secondary Structure
MNKKLDLEQKRLDTVIETITEQIDKLKNETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAADQIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECHH
FRGKLIASAKEITEQFYNTDSSLRFNNRIEKLTDWLNKQIDALEKAELKKPWVEEEIELL
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWVTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVSNESELHEHITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
QKEQHNTIAIICKSAAESAAAYEALNHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHHCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYSDESVRRLFYTACTRAMHELHLYSVGEVSPFVLGADSESFELITTP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]