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The map label for this gene is scrR [H]

Identifier: 218233758

GI number: 218233758

Start: 786906

End: 787892

Strand: Reverse

Name: scrR [H]

Synonym: BCB4264_A0811

Alternate gene names: 218233758

Gene position: 787892-786906 (Counterclockwise)

Preceding gene: 218231206

Following gene: 218235792

Centisome position: 14.54

GC content: 34.45

Gene sequence:

>987_bases
ATGGCTAAAACAATTGCAGATATCGCCAAATTGGCTGGAGTTGCAAAAAGCACAGTCTCTCGTTACTTAAACGGCGGATA
TGTAAGTGATAAAACAAAACTTAAAATCGAAGGTATTATTCAAGAAACAAATTTCTCTCCCAATACATTTGCTCAAAGTT
TAAAAGCAAAAACAACAAATTTAATTGGTGTCATCATCCCCCGATTAGACTCCTTCGCTACAATGAAAACACTTATCGGG
ATCGATAAAACATTACAGGAAAATAACTATCAAATGCTTGTAGCAAATGCAAATCAAACAACCGGAACTGAAATACAAGC
AATTGAAAACTTTATAAAACAAAAGGTAGCTGGCATTATTTTATTAACAAAAACATTAACGAATGAACATCAAAAAATTA
TGGCTAATTCAAACATCCCTATTTTATTCGTCGGGCAAGAATATAAAGATCAATATTGCCTCGTTCACGATGATTATGAT
GCAGCTTATGAGTTAGGGGCATACGTTTTATCGCAAGGCCATCGACATATTGCCTATTTAGGGATAGAAAAAGATGATAT
TTCTGTTGGAATAAATCGAAAAAATGGTTTTCAAAAAGCAATTGAAAATTTAGAACCGACTTGCAACGTTTCATATTACG
AAACAACTTTCCGCATAGAAGATGCCATGAAACAAGTACAACATATTTTAGATAATAATCGCCCAACTCTTATCGTATGT
GCTACAGATAACATCGCTCTTGGCGCAATGAAAGTCATTCACTCCCACTCTCTTTCTGTACCAGGTGATATTTCTGTAAC
AGGATTCGGTGGATATGATATTTCAGAAATGGTACACCCTAGTTTAACGACAATTGCGTTTGACTATGAGTATGCTGGAA
AGCTTGCTGCCACTTCTCTTTCACAGCTTGTTGAAAACAAAACTATACCAAAAATATTACACTCTCGTTATACATTAAAA
ATCCAAGAAAGCGTTGACAAAATATAA

Upstream 100 bases:

>100_bases
ATACGTGAGGTGGTCTTTTCTTTCCCTCTTCTTGTTTACGTCATCTCTAATTCTCCCTATAATAAAGTTAACATTTTTAT
GAATACGAAGGTGAAATACT

Downstream 100 bases:

>100_bases
AGGCGCTCTATAATAAAATTAAAACCGGTTCCACATTTTAAAAACAGGATTTTCAACATCATTTCCCTGTTTTTTATTTT
AACTTTTTACGGAACCGGTT

Product: sucrose operon repressor

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAKTIADIAKLAGVAKSTVSRYLNGGYVSDKTKLKIEGIIQETNFSPNTFAQSLKAKTTNLIGVIIPRLDSFATMKTLIG
IDKTLQENNYQMLVANANQTTGTEIQAIENFIKQKVAGIILLTKTLTNEHQKIMANSNIPILFVGQEYKDQYCLVHDDYD
AAYELGAYVLSQGHRHIAYLGIEKDDISVGINRKNGFQKAIENLEPTCNVSYYETTFRIEDAMKQVQHILDNNRPTLIVC
ATDNIALGAMKVIHSHSLSVPGDISVTGFGGYDISEMVHPSLTTIAFDYEYAGKLAATSLSQLVENKTIPKILHSRYTLK
IQESVDKI

Sequences:

>Translated_328_residues
MAKTIADIAKLAGVAKSTVSRYLNGGYVSDKTKLKIEGIIQETNFSPNTFAQSLKAKTTNLIGVIIPRLDSFATMKTLIG
IDKTLQENNYQMLVANANQTTGTEIQAIENFIKQKVAGIILLTKTLTNEHQKIMANSNIPILFVGQEYKDQYCLVHDDYD
AAYELGAYVLSQGHRHIAYLGIEKDDISVGINRKNGFQKAIENLEPTCNVSYYETTFRIEDAMKQVQHILDNNRPTLIVC
ATDNIALGAMKVIHSHSLSVPGDISVTGFGGYDISEMVHPSLTTIAFDYEYAGKLAATSLSQLVENKTIPKILHSRYTLK
IQESVDKI
>Mature_327_residues
AKTIADIAKLAGVAKSTVSRYLNGGYVSDKTKLKIEGIIQETNFSPNTFAQSLKAKTTNLIGVIIPRLDSFATMKTLIGI
DKTLQENNYQMLVANANQTTGTEIQAIENFIKQKVAGIILLTKTLTNEHQKIMANSNIPILFVGQEYKDQYCLVHDDYDA
AYELGAYVLSQGHRHIAYLGIEKDDISVGINRKNGFQKAIENLEPTCNVSYYETTFRIEDAMKQVQHILDNNRPTLIVCA
TDNIALGAMKVIHSHSLSVPGDISVTGFGGYDISEMVHPSLTTIAFDYEYAGKLAATSLSQLVENKTIPKILHSRYTLKI
QESVDKI

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=330, Percent_Identity=28.4848484848485, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=30.8681672025724, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=25.9615384615385, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790369, Length=292, Percent_Identity=28.7671232876712, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=29.595015576324, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790194, Length=327, Percent_Identity=26.9113149847095, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789068, Length=293, Percent_Identity=25.938566552901, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789202, Length=317, Percent_Identity=25.5520504731861, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787948, Length=313, Percent_Identity=25.2396166134185, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788474, Length=323, Percent_Identity=26.625386996904, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786268, Length=290, Percent_Identity=26.8965517241379, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787580, Length=324, Percent_Identity=24.6913580246914, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787906, Length=254, Percent_Identity=25.9842519685039, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36284; Mature: 36153

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTIADIAKLAGVAKSTVSRYLNGGYVSDKTKLKIEGIIQETNFSPNTFAQSLKAKTTN
CCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
LIGVIIPRLDSFATMKTLIGIDKTLQENNYQMLVANANQTTGTEIQAIENFIKQKVAGII
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEE
LLTKTLTNEHQKIMANSNIPILFVGQEYKDQYCLVHDDYDAAYELGAYVLSQGHRHIAYL
EEEHHHCCCHHHHEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEE
GIEKDDISVGINRKNGFQKAIENLEPTCNVSYYETTFRIEDAMKQVQHILDNNRPTLIVC
EEECCCEEEEECCCCHHHHHHHCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCCCCEEEEE
ATDNIALGAMKVIHSHSLSVPGDISVTGFGGYDISEMVHPSLTTIAFDYEYAGKLAATSL
ECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEEEHHHHCHHHHHHH
SQLVENKTIPKILHSRYTLKIQESVDKI
HHHHHCCCHHHHHHCCEEEEEHHHHCCC
>Mature Secondary Structure 
AKTIADIAKLAGVAKSTVSRYLNGGYVSDKTKLKIEGIIQETNFSPNTFAQSLKAKTTN
CCHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
LIGVIIPRLDSFATMKTLIGIDKTLQENNYQMLVANANQTTGTEIQAIENFIKQKVAGII
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEE
LLTKTLTNEHQKIMANSNIPILFVGQEYKDQYCLVHDDYDAAYELGAYVLSQGHRHIAYL
EEEHHHCCCHHHHEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEE
GIEKDDISVGINRKNGFQKAIENLEPTCNVSYYETTFRIEDAMKQVQHILDNNRPTLIVC
EEECCCEEEEECCCCHHHHHHHCCCCCCCEEEEEEEEEHHHHHHHHHHHHCCCCCEEEEE
ATDNIALGAMKVIHSHSLSVPGDISVTGFGGYDISEMVHPSLTTIAFDYEYAGKLAATSL
ECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEEEHHHHCHHHHHHH
SQLVENKTIPKILHSRYTLKIQESVDKI
HHHHHCCCHHHHHHCCEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550467 [H]