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The map label for this gene is dcuB [H]

Identifier: 218233495

GI number: 218233495

Start: 424776

End: 426089

Strand: Reverse

Name: dcuB [H]

Synonym: BCB4264_A0441

Alternate gene names: 218233495

Gene position: 426089-424776 (Counterclockwise)

Preceding gene: 218235293

Following gene: 218231865

Centisome position: 7.86

GC content: 38.74

Gene sequence:

>1314_bases
ATGTTTTGGCTACAATTTCTTACCTTGTTACTCTGTATTTTTATTGGTGCACGCCTAGGCGGAGTTGGTTTAGGAGTAAT
GGGTGGAGTTGGTATGGCAATACTCGTTTTTGTCTTCCACCTACAACCAACCGCGCCTCCTATCGATGTAATGCTTATGA
TTTTGGCAGTAATTACAGCTGCTGGTGCTTTGCAAGCTGCTGGAGGAATGGACTATCTTGTTCATCTAGCTGAAAAGACA
TTACGAAAAAATCCAAAGCGTATTACTTTTTTTGCTCCAATTGTTACTTATTTATTCACACTATGTGCAGGTACTGGTCA
CGTTGCCTATTCTGTACTTCCTGTTATTGCAGAAGTCTCTCGTGAATCAGGGATTAGACCGGAACGCCCAATGTCGATTG
CCGTAATCGCTTCTCAACAAGCAATTACAGCTAGTCCAATTTCAGCTGCCACAGTTGCTCTTTTAGCAATGTTAGCTGAC
TATAAAATCACCTTATTAGATATTTTAAAAGTAAGTATACCTTCTACTTTCATCGCTTGTATGATAGCTGCATTCGTTGC
TAGTAAGATGGGAAAAGAATTAAATGAAGACCCTGAATACTTAAAACGATTAAAAGAAGGAATGATTCCTAAGCTTGAAG
AGAAAAAAGAATTTGTAGGTGTAAAGGGCGCAAAATTATCAGTTATCCTTTTCCTAGTAGGAACCTTCCTTGTTGTACTT
CTTGGTTCATTTGAAGCACTTCGTCCAGGATGGATAGTTGATGGGAAGTTAGCTCGTCTTTCCATGCCGAACACAATTGA
GATGGTTATGTTAACTATCGCGGCTCTTATTATTATTTTCTGTAAACCCAATGTAGAAAGCATTGTGTCTGGTAACGTCT
TTAAAGCAGGGGCAACAGCAGTTGTTGCTATTTTTGGTATCGCTTGGATGGGAGATACTTTCTTTAATGGAAACTTAAAT
ATGATTCAAGGATCCATTCAGCATTTAGTAACAAGTGCACCTTGGCTATTTGCCATCGCACTATTCATTCTATCTATTTT
ACTGTACAGCCAAGCAGCAACTGTTCGTGCCTTAATGCCACTTGGACTATCTCTTGGCATTCCACCAGCGCTACTGATTG
CGATGTTCCCTGCAGTAAATGGATATTTCTTCATTCCAAACTATGGAACAATCGTTGCTGCCATTAACTTTGATCGTACT
GGTACAACAAGTATCGGTAAATACGTATTAAATCATAGTTTTATGATTCCTGGCCTAATTGCAACATTTACTTCTATCGG
AATTGGAATGCTCTTAATTTCAATTATGTTTTAA

Upstream 100 bases:

>100_bases
TGTATAAATAACAAGGATTTCTTCGGGTATTTATTTAATTTTCATTCAAATTAAACTATTCGAATATATCTTAACTAATG
AATTTCGGAGGTAGTTTATC

Downstream 100 bases:

>100_bases
AGAAAAAGCACAAACCTTTATTTAAAAAGGTTTGTGCTTTTTTAATCAAATGTTTGTTTAAATTTTGGGGCAGTCTATTT
CTCCATGTAGCACTTAAAAT

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMDYLVHLAEKT
LRKNPKRITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLAD
YKITLLDILKVSIPSTFIACMIAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVKGAKLSVILFLVGTFLVVL
LGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLN
MIQGSIQHLVTSAPWLFAIALFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRT
GTTSIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF

Sequences:

>Translated_437_residues
MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMDYLVHLAEKT
LRKNPKRITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLAD
YKITLLDILKVSIPSTFIACMIAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVKGAKLSVILFLVGTFLVVL
LGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLN
MIQGSIQHLVTSAPWLFAIALFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRT
GTTSIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF
>Mature_437_residues
MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMDYLVHLAEKT
LRKNPKRITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLAD
YKITLLDILKVSIPSTFIACMIAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVKGAKLSVILFLVGTFLVVL
LGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLN
MIQGSIQHLVTSAPWLFAIALFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRT
GTTSIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=438, Percent_Identity=44.2922374429224, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1790565, Length=412, Percent_Identity=42.2330097087379, Blast_Score=301, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46827; Mature: 46827

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AGALQAAGGMDYLVHLAEKTLRKNPKRITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVS
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKITLLDILKVSIPSTFIAC
HHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
MIAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVKGAKLSVILFLVGTFLVVL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFCKPNVESIVSGNVFKAGATA
HCCHHHCCCCCEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHH
VVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIALFILSILLYSQAATVRALMP
HHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRTGTTSIGKYVLNHSFMIPGLI
CCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
ATFTSIGIGMLLISIMF
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AGALQAAGGMDYLVHLAEKTLRKNPKRITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVS
HHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKITLLDILKVSIPSTFIAC
HHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
MIAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVKGAKLSVILFLVGTFLVVL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFCKPNVESIVSGNVFKAGATA
HCCHHHCCCCCEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHH
VVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIALFILSILLYSQAATVRALMP
HHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRTGTTSIGKYVLNHSFMIPGLI
CCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHH
ATFTSIGIGMLLISIMF
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]