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The map label for this gene is ytnA [H]

Identifier: 218232993

GI number: 218232993

Start: 718461

End: 719852

Strand: Reverse

Name: ytnA [H]

Synonym: BCB4264_A0725

Alternate gene names: 218232993

Gene position: 719852-718461 (Counterclockwise)

Preceding gene: 218233719

Following gene: 218230996

Centisome position: 13.28

GC content: 37.79

Gene sequence:

>1392_bases
ATGCAGCACACAAACAAATCTGGAACTTTAAATCGTGGTTTAAAAGAACGACATATTACTTTAATGTCACTGGGCTCAGC
TATTGGCGTTGGGCTATTTTTAGGATCCGCTTCCGCCATTAAACTAGCAGGTCCTTCTATTTTGCTAGGCTATATGATTG
CCGGTCTCGTTATTTTTTTCATTATGCGAGCGCTTGGGGAAATGGCAATTGAACAACCTGTTGCTGGTTCTTTTAGTAAA
TATGCATATGATTATATTGGACCACTCGCTGGTTATATTACTGGTTGGAATTACTGGTTCTTATGGGTTGTTACTTGTAT
GGCTGAGATTACAGCAGCTGGTATTTACATGCAGTACTGGTTCCCAGATATCCCGCGCTGGACTTGGGCATTACTTGCTC
TATTATTAATGAGCGCTTTTAACTTCTTATCGGTAAAAGTATTTGGAGAACTTGAGTTTTGGTTTGCTCTCATTAAAATT
GTCACAATTATCTGTATGATAGTAGTCGGAGCTGGTATTATTTTATTCGGATTCGGAAACGGTGGTATCGCTACTGGTAT
TTCAAATCTTTGGTCACATGGTGGCTGGTTCCCAAATGGATTTTCTGGGTTACTACTCTCCATGCAGATGGTACTATTCG
CTTATTTAGGCGTTGAATTAATCGGTGTTACAGCTGGTGAGGCTCAAAATCCGAAGAAAACACTCGCAAAGGCAATCGAT
AACGTATTTTGGAGAATTCTACTCTTTTACGTTGGGGCATTATTCGTTATGATGGCAATTTATCCATGGAACGAACTTGG
TGAGAAAGGCAGTCCATTCGTATTAACATTCCAACAAATTGGTATCGCAAAAGCAGCAGGTATTATTAACTTTGTCGTAT
TAACAGCAGCTCTTTCTTCTTGTAACGGTGGTTTATTTAGTACAGGCCGTATGCTATATACATTAGCTCAGCAGAAAAAA
GCTCCTGAAAGATTTGGTCGTTTAAATAAAAATGGCATTCCAAGCCAAGGAATTGTAGCAACTGCTATCGTTTTACTAAT
TGGTGTTATATTAAACTATCTCGTACCTGCAAAGGTATTTACATGGCTTACTAGCATTTCAACTTTCGGTGCAATTTGGA
CTTGGGGAATTATATTAGTCGCTCAAATTAAATTCCGTAAAAGCTTGCCTACTCAAAATAAACAAAAGTTATCGTATAAA
ATGCCTTTATACCCATTAAGCTCATATTTCTCACTCATTTTCCTTGTATTAGTATTAGGTATAATGGCGTATTCAGAAGA
TACACGAATTGCATTGATTGTCGGCCCAATTTGGCTTATCGGCTTAGCAATCGTATATTACATGAAAGGGTTTCATAAGA
TTGATGAAACACCTAACTCAAAAATTAGTTAA

Upstream 100 bases:

>100_bases
TTTTGTAGCATAACAGATAGAAATGTTTTATAATTTGAAATAGTTAAATATTTAGTAAACGCATTCAAATATCGTTCACT
CTACAAGGGGGATTCTTCTT

Downstream 100 bases:

>100_bases
GCAAAACATCCCTTCCTTATTACTTGGAAGGGATGTTTTTATATCTATATAAATATTTCTCAACAAAATTCACGGTATTT
TTACAATTTTTTAATATTTT

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MQHTNKSGTLNRGLKERHITLMSLGSAIGVGLFLGSASAIKLAGPSILLGYMIAGLVIFFIMRALGEMAIEQPVAGSFSK
YAYDYIGPLAGYITGWNYWFLWVVTCMAEITAAGIYMQYWFPDIPRWTWALLALLLMSAFNFLSVKVFGELEFWFALIKI
VTIICMIVVGAGIILFGFGNGGIATGISNLWSHGGWFPNGFSGLLLSMQMVLFAYLGVELIGVTAGEAQNPKKTLAKAID
NVFWRILLFYVGALFVMMAIYPWNELGEKGSPFVLTFQQIGIAKAAGIINFVVLTAALSSCNGGLFSTGRMLYTLAQQKK
APERFGRLNKNGIPSQGIVATAIVLLIGVILNYLVPAKVFTWLTSISTFGAIWTWGIILVAQIKFRKSLPTQNKQKLSYK
MPLYPLSSYFSLIFLVLVLGIMAYSEDTRIALIVGPIWLIGLAIVYYMKGFHKIDETPNSKIS

Sequences:

>Translated_463_residues
MQHTNKSGTLNRGLKERHITLMSLGSAIGVGLFLGSASAIKLAGPSILLGYMIAGLVIFFIMRALGEMAIEQPVAGSFSK
YAYDYIGPLAGYITGWNYWFLWVVTCMAEITAAGIYMQYWFPDIPRWTWALLALLLMSAFNFLSVKVFGELEFWFALIKI
VTIICMIVVGAGIILFGFGNGGIATGISNLWSHGGWFPNGFSGLLLSMQMVLFAYLGVELIGVTAGEAQNPKKTLAKAID
NVFWRILLFYVGALFVMMAIYPWNELGEKGSPFVLTFQQIGIAKAAGIINFVVLTAALSSCNGGLFSTGRMLYTLAQQKK
APERFGRLNKNGIPSQGIVATAIVLLIGVILNYLVPAKVFTWLTSISTFGAIWTWGIILVAQIKFRKSLPTQNKQKLSYK
MPLYPLSSYFSLIFLVLVLGIMAYSEDTRIALIVGPIWLIGLAIVYYMKGFHKIDETPNSKIS
>Mature_463_residues
MQHTNKSGTLNRGLKERHITLMSLGSAIGVGLFLGSASAIKLAGPSILLGYMIAGLVIFFIMRALGEMAIEQPVAGSFSK
YAYDYIGPLAGYITGWNYWFLWVVTCMAEITAAGIYMQYWFPDIPRWTWALLALLLMSAFNFLSVKVFGELEFWFALIKI
VTIICMIVVGAGIILFGFGNGGIATGISNLWSHGGWFPNGFSGLLLSMQMVLFAYLGVELIGVTAGEAQNPKKTLAKAID
NVFWRILLFYVGALFVMMAIYPWNELGEKGSPFVLTFQQIGIAKAAGIINFVVLTAALSSCNGGLFSTGRMLYTLAQQKK
APERFGRLNKNGIPSQGIVATAIVLLIGVILNYLVPAKVFTWLTSISTFGAIWTWGIILVAQIKFRKSLPTQNKQKLSYK
MPLYPLSSYFSLIFLVLVLGIMAYSEDTRIALIVGPIWLIGLAIVYYMKGFHKIDETPNSKIS

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=367, Percent_Identity=25.0681198910082, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI258645169, Length=405, Percent_Identity=22.962962962963, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI258614003, Length=406, Percent_Identity=22.9064039408867, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI258614005, Length=406, Percent_Identity=22.9064039408867, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507047, Length=444, Percent_Identity=22.5225225225225, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI114326544, Length=430, Percent_Identity=21.8604651162791, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI114326550, Length=430, Percent_Identity=21.8604651162791, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI181337167, Length=319, Percent_Identity=23.1974921630094, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=48.8069414316703, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=51.9565217391304, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1786789, Length=443, Percent_Identity=44.4695259593679, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1786302, Length=451, Percent_Identity=45.4545454545455, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790653, Length=458, Percent_Identity=43.4497816593886, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI87081708, Length=467, Percent_Identity=37.9014989293362, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI87081915, Length=433, Percent_Identity=39.9538106235566, Blast_Score=331, Evalue=5e-92,
Organism=Escherichia coli, GI1788480, Length=441, Percent_Identity=38.0952380952381, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1789017, Length=443, Percent_Identity=36.117381489842, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI87081869, Length=472, Percent_Identity=21.8220338983051, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI2367353, Length=341, Percent_Identity=23.4604105571848, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=366, Percent_Identity=23.224043715847, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=449, Percent_Identity=25.1670378619154, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324061, Length=480, Percent_Identity=31.25, Blast_Score=249, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6324924, Length=436, Percent_Identity=33.256880733945, Blast_Score=223, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6322892, Length=433, Percent_Identity=33.256351039261, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6320772, Length=446, Percent_Identity=30.7174887892377, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324990, Length=439, Percent_Identity=31.4350797266515, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=30.2272727272727, Blast_Score=199, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6319824, Length=432, Percent_Identity=27.3148148148148, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6320717, Length=436, Percent_Identity=27.5229357798165, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321629, Length=435, Percent_Identity=28.5057471264368, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=30.9823677581864, Blast_Score=186, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320251, Length=430, Percent_Identity=28.3720930232558, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319542, Length=436, Percent_Identity=26.8348623853211, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6321053, Length=473, Percent_Identity=27.4841437632135, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6322967, Length=397, Percent_Identity=25.9445843828715, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319543, Length=412, Percent_Identity=26.2135922330097, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324981, Length=403, Percent_Identity=25.8064516129032, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319608, Length=432, Percent_Identity=26.1574074074074, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320364, Length=505, Percent_Identity=25.7425742574257, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI221512776, Length=424, Percent_Identity=20.7547169811321, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24666159, Length=424, Percent_Identity=20.7547169811321, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24668806, Length=342, Percent_Identity=24.5614035087719, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356285, Length=342, Percent_Identity=24.5614035087719, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24668802, Length=342, Percent_Identity=24.5614035087719, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI161077963, Length=368, Percent_Identity=23.6413043478261, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667468, Length=349, Percent_Identity=23.2091690544413, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281366235, Length=362, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007820, Length=362, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007818, Length=332, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725152, Length=332, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50922; Mature: 50922

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHTNKSGTLNRGLKERHITLMSLGSAIGVGLFLGSASAIKLAGPSILLGYMIAGLVIFF
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
IMRALGEMAIEQPVAGSFSKYAYDYIGPLAGYITGWNYWFLWVVTCMAEITAAGIYMQYW
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FPDIPRWTWALLALLLMSAFNFLSVKVFGELEFWFALIKIVTIICMIVVGAGIILFGFGN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GGIATGISNLWSHGGWFPNGFSGLLLSMQMVLFAYLGVELIGVTAGEAQNPKKTLAKAID
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
NVFWRILLFYVGALFVMMAIYPWNELGEKGSPFVLTFQQIGIAKAAGIINFVVLTAALSS
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CNGGLFSTGRMLYTLAQQKKAPERFGRLNKNGIPSQGIVATAIVLLIGVILNYLVPAKVF
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TWLTSISTFGAIWTWGIILVAQIKFRKSLPTQNKQKLSYKMPLYPLSSYFSLIFLVLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHH
IMAYSEDTRIALIVGPIWLIGLAIVYYMKGFHKIDETPNSKIS
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQHTNKSGTLNRGLKERHITLMSLGSAIGVGLFLGSASAIKLAGPSILLGYMIAGLVIFF
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
IMRALGEMAIEQPVAGSFSKYAYDYIGPLAGYITGWNYWFLWVVTCMAEITAAGIYMQYW
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FPDIPRWTWALLALLLMSAFNFLSVKVFGELEFWFALIKIVTIICMIVVGAGIILFGFGN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GGIATGISNLWSHGGWFPNGFSGLLLSMQMVLFAYLGVELIGVTAGEAQNPKKTLAKAID
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
NVFWRILLFYVGALFVMMAIYPWNELGEKGSPFVLTFQQIGIAKAAGIINFVVLTAALSS
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CNGGLFSTGRMLYTLAQQKKAPERFGRLNKNGIPSQGIVATAIVLLIGVILNYLVPAKVF
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TWLTSISTFGAIWTWGIILVAQIKFRKSLPTQNKQKLSYKMPLYPLSSYFSLIFLVLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHH
IMAYSEDTRIALIVGPIWLIGLAIVYYMKGFHKIDETPNSKIS
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]