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The map label for this gene is dgk [H]

Identifier: 218232701

GI number: 218232701

Start: 23131

End: 23766

Strand: Reverse

Name: dgk [H]

Synonym: BCB4264_A0020

Alternate gene names: 218232701

Gene position: 23766-23131 (Counterclockwise)

Preceding gene: 218231526

Following gene: 218235731

Centisome position: 0.44

GC content: 33.96

Gene sequence:

>636_bases
GTGACCGGAGTACCATTTATCACGGTTGAAGGACCAATTGGTGTTGGAAAAACTTCACTTGCGAAGGAAATTTCAACTCA
CATGCAACTCCACTTACTAAAAGAGATTGTTGATGAAAATCCCTTTTTAGGAAAGTTCTATGAAGACATCGACGAATGGA
GTTTTCAAACAGAGATGTTCTTTCTTTGTAATAGATACAAACAATTAGAAGACATTAACATAAAGTACTTGAATCAAAGG
AAACCAGTAGTAGCGGATTACCATATCTTTAAAAATTTAATTTTTGCATCCCGCACATTAAAAGACTCTCAATATGACAA
ATACATGCAAATTTATCGTATCCTTACACAAGATATGCCTGTGCCAAATGTCATTGTTTATTTAACAGCTAGCCTAAAAA
CATTGCAAAAACGAATCGCCATGCGCGGAAGAGAATTTGAAAAAAACATGGATCCAAATTACTTACTACAGCTCACAAAA
GATTATGAAACAGCAATGGATGCTTTTAAAAAAGATCATCCGGAAATACCAGTATTGAAATTTAATGGCGACGATATGGA
TTTTGTAAAAAATCCTGATGATTTAAACGTTATCCTATCTGCCCTTCAAAATACTCTCTTAAAGGAGTCGAAATAA

Upstream 100 bases:

>100_bases
TATATCAAATTAACCCGCTCGCTTCCCTCTTGTGCTACAATAATTCTGTTTTGTGTTTTTAGTAGTCACGGTAAATCACT
GATTGAAAGGAGGAAACAGC

Downstream 100 bases:

>100_bases
TAATGAATTTAAGGCAAAAATATGATATACCCAATGACGCAGTAATCACTATCGCCGGAACGGTAGGTGTGGGTAAATCA
ACTATGACAACTGCATTAGC

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQR
KPVVADYHIFKNLIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLKTLQKRIAMRGREFEKNMDPNYLLQLTK
DYETAMDAFKKDHPEIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Sequences:

>Translated_211_residues
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQR
KPVVADYHIFKNLIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLKTLQKRIAMRGREFEKNMDPNYLLQLTK
DYETAMDAFKKDHPEIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK
>Mature_210_residues
TGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQRK
PVVADYHIFKNLIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLKTLQKRIAMRGREFEKNMDPNYLLQLTKD
YETAMDAFKKDHPEIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24716; Mature: 24585

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FLCNRYKQLEDINIKYLNQRKPVVADYHIFKNLIFASRTLKDSQYDKYMQIYRILTQDMP
HHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
VPNVIVYLTASLKTLQKRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHPEIPVLK
CCCEEEHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNGDDMDFVKNPDDLNVILSALQNTLLKESK
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMF
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FLCNRYKQLEDINIKYLNQRKPVVADYHIFKNLIFASRTLKDSQYDKYMQIYRILTQDMP
HHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
VPNVIVYLTASLKTLQKRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHPEIPVLK
CCCEEEHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNGDDMDFVKNPDDLNVILSALQNTLLKESK
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]