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The map label for this gene is rocC [H]

Identifier: 218231999

GI number: 218231999

Start: 730749

End: 732155

Strand: Reverse

Name: rocC [H]

Synonym: BCB4264_A0738

Alternate gene names: 218231999

Gene position: 732155-730749 (Counterclockwise)

Preceding gene: 218234683

Following gene: 218234032

Centisome position: 13.51

GC content: 38.88

Gene sequence:

>1407_bases
ATGAATCAACAAATTGAACAAACAGATTTAAAACGAACAATGAAAAGTAGACACCTATTTATGATTGCACTCGGCGGTGT
TATCGGAACCGGGTTATTTATGGGATCTGGTCAAATTGTCCATAATGCCGGACCTGGTGGTGCTATTCTTGCATTTTTAG
TCGGTGGATTTGTTATGTATTTAACGATGTTATGTCTTGGTGAATTATCCGTCGCTATGCCAGAAGCAGGTTCATTCCAA
AGTTATGCAAGCAAATTCATTTCACCTGGTTTTGGATTTGTTGTCGGTTGGATGTATTGGTTAAATTGGGCTGTTACAGT
TGGCGTAGAGTTAACAACTGTAAGTATTTTAATGAAACGCTGGTTTCCAGACGTTTCTTCCTGGATTTGGTGCGTTACAT
TTGCAGCAGCACTCTTCCTCGTAAACGCTTTATCAGCAAAAGCATATGCAGAAGCAGAGTTTTGGTTCGCAAGTGTAAAA
GTCGCAACAATTGTTATTTTCATCGTACTTGGCGGCGCTGTTATGTTCGGTCTACTAGACTTTAATGGAAAGCCAGCTCC
AATGCTTCATAATTTCACTGAAAATGGCGGGCTATTTCCAAATGGTGCATTAGCTGTTCTTCTTACGATGATTACAGTAA
ATTACTCCTTCCAAGGAACAGAATTAATCGGAATCGCTTCAGGCGAAAGTGAAAATCCTGAAAAAACAATTCCAAAAGCA
ATTAAAAACACAATTTGGCGAACTCTCTTCTTCTTCGTCTTAGCGATATCAGTTGTTGTAGGTTTACTCCCATGGCAAGA
GGCTAATCTAGTCGAAAGTCCCTTTGTACTTGTATTTGATGTAGCCGGCGTCCCATATGCAGCAGACATTATGAACTTTG
TTATTATTACAGCTGTATTATCCGTTGCTAACTCTGGTCTATACGCAAATTCTCGTATGCTGTGGGCGATGGCAAAACAA
GGAATGGCAAGTCCAGCATTTACGAAATTAACTAAAAAAGGTGTACCGCTAAACGCATTAATTTTCAGCCTAATTTTCGC
TAGCCTGTCCTTACTAACAAGTGTATTTGCGGCAGATACTGTCTTTCTAGTTTTAACATCTATTGCAGCAATGGCTGCCG
TTGTCGTTTGGATGTCAATCGCCGCTTCACAGTTTTTCTTCCGTAGAAATTTCGTGAAAAATGGTGGCAACATAAATGAT
TTAAAATATCGTACACCGCTCTATCCACTAGTTCCAATCGTAGCGTTCTCGCTCAATTTCATTACATTTGTTAGTTTGGC
TTTCATTCCAGATCAAAGAATTGCTCTTTATTGCGGCATTCCATTTATGATTATTTGTTACATTTTATACCAAGTTAAAT
ATAAAAAAATTGTCACACTTGAACAGCCACGAACTGTCATACGATAA

Upstream 100 bases:

>100_bases
TAGCAAATAAACCGAGTGTGTGTTGCATCCCCCACTAATGATTAAAAACTCAGAATAAAACGAAGTTCACACATTCAAGA
AAATACGGGGTGAGGGGCAT

Downstream 100 bases:

>100_bases
ATAAACTAAATATACAAAATATTCAGCTATCTTTCTTATGATAAGATAGCTTTTTTCTATTTCTTGGATATCCTGGTATA
ACTTTATTTATCTTAAAATT

Product: amino-acid permease RocC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNQQIEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVIFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSVFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGNIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMIICYILYQVKYKKIVTLEQPRTVIR

Sequences:

>Translated_468_residues
MNQQIEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVIFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSVFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGNIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMIICYILYQVKYKKIVTLEQPRTVIR
>Mature_468_residues
MNQQIEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVIFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSVFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGNIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMIICYILYQVKYKKIVTLEQPRTVIR

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=357, Percent_Identity=24.9299719887955, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110347453, Length=344, Percent_Identity=23.2558139534884, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI181337167, Length=337, Percent_Identity=25.8160237388724, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87081708, Length=465, Percent_Identity=50.5376344086022, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1788480, Length=467, Percent_Identity=42.8265524625268, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1786302, Length=455, Percent_Identity=35.8241758241758, Blast_Score=297, Evalue=8e-82,
Organism=Escherichia coli, GI48994972, Length=464, Percent_Identity=36.2068965517241, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1786602, Length=459, Percent_Identity=36.1655773420479, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1786789, Length=430, Percent_Identity=34.8837209302326, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=35.2216748768473, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789017, Length=467, Percent_Identity=33.1905781584582, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790653, Length=439, Percent_Identity=33.9407744874715, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081869, Length=240, Percent_Identity=30, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082250, Length=337, Percent_Identity=27.0029673590504, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082023, Length=332, Percent_Identity=25.9036144578313, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367353, Length=336, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=376, Percent_Identity=24.468085106383, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=383, Percent_Identity=23.7597911227154, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320772, Length=478, Percent_Identity=31.5899581589958, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6324061, Length=475, Percent_Identity=32, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324553, Length=414, Percent_Identity=33.3333333333333, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320717, Length=419, Percent_Identity=31.0262529832936, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=413, Percent_Identity=31.9612590799031, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321629, Length=488, Percent_Identity=27.6639344262295, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6319543, Length=412, Percent_Identity=30.0970873786408, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6324059, Length=474, Percent_Identity=31.0126582278481, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6319824, Length=487, Percent_Identity=28.952772073922, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324990, Length=487, Percent_Identity=28.7474332648871, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319542, Length=413, Percent_Identity=30.9927360774818, Blast_Score=202, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6324924, Length=487, Percent_Identity=28.952772073922, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320251, Length=413, Percent_Identity=30.2663438256659, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6321053, Length=420, Percent_Identity=27.1428571428571, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322967, Length=471, Percent_Identity=29.723991507431, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6324981, Length=484, Percent_Identity=29.1322314049587, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=26.7898383371824, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320364, Length=541, Percent_Identity=24.5841035120148, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24667468, Length=378, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51227; Mature: 51227

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQIEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMY
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHH
LTMLCLGELSVAMPEAGSFQSYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKR
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVKVATIVIFIVLGGAVMFGLLD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYANSRMLWAMAKQGMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSVFAADT
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGNINDLKYRTPLYPLVPIVAFSLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
ITFVSLAFIPDQRIALYCGIPFMIICYILYQVKYKKIVTLEQPRTVIR
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEECCCHHHCC
>Mature Secondary Structure
MNQQIEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMY
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHH
LTMLCLGELSVAMPEAGSFQSYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKR
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVKVATIVIFIVLGGAVMFGLLD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYANSRMLWAMAKQGMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSVFAADT
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGNINDLKYRTPLYPLVPIVAFSLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
ITFVSLAFIPDQRIALYCGIPFMIICYILYQVKYKKIVTLEQPRTVIR
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]