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The map label for this gene is glpT [H]

Identifier: 218231629

GI number: 218231629

Start: 682248

End: 683597

Strand: Reverse

Name: glpT [H]

Synonym: BCB4264_A0692

Alternate gene names: 218231629

Gene position: 683597-682248 (Counterclockwise)

Preceding gene: 218230866

Following gene: 218236076

Centisome position: 12.61

GC content: 39.26

Gene sequence:

>1350_bases
ATGTTTTTCACACAATTATTTAAACCTGCGCCCCACGCGGAACGCTTACCAGCTGATCGCGTTGATAGCGAATACCGTAA
ATTACGTTTACAAGTATTCTTAGGTATCTTCATCGGTTATGCAGGTTACTACTTTGTTCGAAAAAACTTTTCACTAGCAA
TGCCATACTTAATCGAGCAAGGCTTTAGTAAAGGGGAACTTGGGGTTATCCTTTCAGCAGTTTCTATTGCTTACGGATTA
AGTAAATTTCTTATGGGTATCGTATCCGATCGTTGTAATCCTCGCTACTTTTTAGCAGCTGGGCTATTTTTATCAGGTAT
CATTAATATTATTTTCGGCTCATTTTCTTTCATTACAACGAGCATTATACTTATGTTTGTACTTCAGTTTTTAAATGGAT
GGGTACAAGGTATGGGATGGCCTCCTTGTGGTCGTACGATGGTTCACTGGTTCTCTATTAGCGAACGTGGTACAAAAATG
TCCATTTGGAACGTCGCTCATAATGTTGGCGGAGCGCTTATGCCTTCCCTTGTAACATTAGGCTTATACTTCTTCGCAGA
TGACTGGAAAAGTATTTTTTACTTCCCAGGTATTCTTTCAATTTTAGTTGGTATTTATGTATTAATTACGATGAAAGATA
CGCCTCAATCTTGCGGACTACCTTCTATTGAAGAACATACTGGGGAATATCCACCAGATGAAAAAGTAAAAGATCGCGAA
CGCGAGCTTTCAGTAAAGGAAATTTTATTTAAATACGTATTAAACAATAAGTTTTTATGGTACATCGCTATTGCGAACGT
TTTCGTATATTTCGTACGTTACGGCGTTGTAGACTGGGCTCCTACTTATTTAGTAGAAGAAAAAAGCTTTACTCATAGTA
GCTCACGTACTGCTTACGCTCTATATGAATGGGCTGGTATTCCAGGTACACTTCTTTGCGGATGGATGAGTGATAAACTA
TTTAAAGGACGTCGTGCACCTGCTGGTATTTTATTTATGGTTGGTGTATTTATCGCAGTTCTTGTTTACTGGTTAAACCC
TCCTGGTAATCCAATGGTTGATAGTATCGCACTTGTCGCAATTGGATTTTTAATTTACGGACCGGTTATGTTAATTGGTC
TACACGCTCTAGATTTAGCACCAAAGAAAGCTGCTGGAACTGCAGCAGGCTTAACTGGATTCTTCGGTTACTTAGGCGGA
GCAGCTTTCGCTAGTGCAGCTATGGGCTTTATCGTAGATGCATTCGGATGGGATGGCGGATTCATCTTATTACTTGCATC
TTGCGTACTTGCAATGTTCTTCCTTGCTCTTACTTTAAATACAGGGTCAGTAAAATCAAAACAAGCTTAA

Upstream 100 bases:

>100_bases
GCTATGAATCATAAAAAAGGAAACTTTTTTATATTTCATGGCCTTTTTATGTTCTCTGTCTTAAAACGCTTCGAATTAAT
TAGGGGAGGATTTTCATTTT

Downstream 100 bases:

>100_bases
ATAACATATAACAAGCATAAAAATAGCTCTTAGCATTTACATACATGCTAAGAGCTATTTTTTATTTTCATTGCTGTTCC
TACTAATGATAACAACCAAT

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFFTQLFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKVKDRE
RELSVKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLNTGSVKSKQA

Sequences:

>Translated_449_residues
MFFTQLFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKVKDRE
RELSVKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLNTGSVKSKQA
>Mature_449_residues
MFFTQLFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKVKDRE
RELSVKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLNTGSVKSKQA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4503847, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219483, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219543, Length=460, Percent_Identity=27.6086956521739, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI256219564, Length=369, Percent_Identity=26.5582655826558, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI223717983, Length=470, Percent_Identity=25.7446808510638, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI38093649, Length=470, Percent_Identity=25.7446808510638, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI46361976, Length=463, Percent_Identity=23.9740820734341, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI49619231, Length=416, Percent_Identity=22.8365384615385, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14150047, Length=330, Percent_Identity=23.030303030303, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788573, Length=444, Percent_Identity=60.3603603603604, Blast_Score=556, Evalue=1e-160,
Organism=Escherichia coli, GI87082310, Length=436, Percent_Identity=37.8440366972477, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI2367259, Length=445, Percent_Identity=33.2584269662921, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI2367379, Length=420, Percent_Identity=24.7619047619048, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789515, Length=396, Percent_Identity=25.2525252525253, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082320, Length=438, Percent_Identity=23.972602739726, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789152, Length=410, Percent_Identity=24.1463414634146, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=427, Percent_Identity=26.463700234192, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17564204, Length=364, Percent_Identity=27.4725274725275, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=439, Percent_Identity=25.0569476082005, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=439, Percent_Identity=25.0569476082005, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI133930953, Length=460, Percent_Identity=23.0434782608696, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17542316, Length=452, Percent_Identity=24.1150442477876, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17561094, Length=399, Percent_Identity=22.0551378446115, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539138, Length=314, Percent_Identity=23.8853503184713, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24656866, Length=470, Percent_Identity=23.8297872340426, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45550478, Length=470, Percent_Identity=23.8297872340426, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656861, Length=470, Percent_Identity=23.8297872340426, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49713; Mature: 49713

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]