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The map label for this gene is dppE [H]

Identifier: 218231583

GI number: 218231583

Start: 190340

End: 191980

Strand: Reverse

Name: dppE [H]

Synonym: BCB4264_A0219

Alternate gene names: 218231583

Gene position: 191980-190340 (Counterclockwise)

Preceding gene: 218230899

Following gene: 218232185

Centisome position: 3.54

GC content: 36.75

Gene sequence:

>1641_bases
ATGAAGAAAAAAGTTGTACCTGTTGTTGCATCTGTTTTAGGGGCAAGTCTATTACTAACTGCTTGCGGGGGAAATAAAGA
TAATGCAAGCGGAGCGAAAGCAAACGATAAAGCACCTGATAAACAGGCAATTAACTTATCATTCGCTTCAGAAATTCCAA
CAATGGATGTTGCAAAAGCAACGGATGGGGAATCCATGAACGTAATGCGTAATGTTTTTGAAGGGCTATATGCAATGGGA
GAAGATAATAAACCGGTTCCTGGTGTCGCTGAGTCGGTTGACATTAGTCCCGATAAAACAAAATATACATTCCATCTCCG
TGATTCAAAATGGTCAAACGGTACTCCTGTTACAGCAAAGGACTTTGCCTTCGCTTGGCAACGTGCCGTAAATCCTGATA
CAGCAGCTGAATACGCATTCTTATTCTTCGATATAAAGAATGCGAAACAAATAAACCAAAAACAATTGCCAATTGATCAA
CTAGGGGTCAAAGCTGTTGATGATAAAACGTTAGAAGTACAACTAGACCGTCCTGTTCCCTACTTCTTAAGCTTAACTAC
ATTCTCAACATTCTTACCAATTAATGAAGAGTACTTAAAGTCTCAAGGCGATAAATATGGTTTAGAAACAAATCATTTAA
TTTATAACGGTGCTTTCACATTAGATAACTGGAAACATGAACAAAGCTTCCAATTGAAGAAAAATCCTAACTATTGGGAT
GCTAAAACTGTAAAATTAGAAGAAATCAACTTCAATGTCGTTAAAGATAAGTCTACAGAAGTGAACTTATATGATTCAGG
ACAAATTGATCGTGTTGCTTTAACTGCAGAGTTTGTTGATAAATATAAGAGCGATCCAAACTTCAAAGAACGCGCTGAAG
TCGGCATTCAATTCTTACGATTAAATCAGAAAAATGAAACATTAAAAAATCAACATGCACGCCTTGCTATTAACGGCGCA
ATGAATAAAAAAGCTTACGTAGAAACAATCTTAAATAACGGCGCTGTTCCAGCTGAAGGAATGGTTCCTGCGAAATTTGC
AAAGAGTCCAGAAGGCAATGACTTCCGTAAAGAAAATGGAAATCTAGTCAAGGATGATGTGAAAACAGCGAAAGAAAACT
GGAAAAAAGCAAAACAAGAACTTGGTACTGACAAAGTAACAATCGAACTATTAACAAGTGACAATGCTTTAGCTAAAAAG
ACTGGAGAATATTTAAAAGGTGAATTAGAAAAGAACCTAGATGGATTAACAGTGAATTTAAAACCACAACCACGTAAACA
ACAGCTAAAACTACTATTAAGTGGTGACTATGAAATTGGTATTGACGGCTGGGGCCCTGACTTCGCTGATCCAATTACAT
TCTTAGATTTATTTACAACAGATAGTGCTTATAACTTCGATAAATACTCTAACAAAGAGTACGATGAGCTAATTCATAAA
GTGAAAACTGATTTAGCTGGCGATGAAAAAGCACGCTTTGAAGCAATGAAGCAAGCTGAAAAAATTCTATTACAAGACGG
CGCTGTCGCTCCTTTATACCAACAAGGCCGTTCTTACTTACAACGCTCTTTCATTAAAGGACTTGTAACAACTGACTTCG
GTGGTGAGTTTAACTACAAGTGGACAGAAGTTACAAAATAA

Upstream 100 bases:

>100_bases
TATAAACAAATATTTATAATAGGTTTTATCTCCTTCTATAGCTACTTCAAGACACGGACATTATGACGTTACGAACAACA
CATTTAGGGAGGAACGAACA

Downstream 100 bases:

>100_bases
TAAGTGCTAATAAAAAGGTATCCCACCGAGGATACCTTTTTATTTTATACTTCTTTAACTACAGAGCTTCTTCTTCCCTT
TACCATTCCTTTTATAGCTA

Product: putative oligopeptide ABC transporter, oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPVPGVAESVDISPDKTKYTFHLRDSKWSNGTPVTAKDFAFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPIDQ
LGVKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKSDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMVPAKFAKSPEGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVTK

Sequences:

>Translated_546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPVPGVAESVDISPDKTKYTFHLRDSKWSNGTPVTAKDFAFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPIDQ
LGVKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKSDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMVPAKFAKSPEGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVTK
>Mature_546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPVPGVAESVDISPDKTKYTFHLRDSKWSNGTPVTAKDFAFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPIDQ
LGVKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKSDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMVPAKFAKSPEGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVTK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=544, Percent_Identity=31.25, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI87081878, Length=516, Percent_Identity=30.8139534883721, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789397, Length=520, Percent_Identity=27.6923076923077, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787762, Length=453, Percent_Identity=25.3863134657837, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787052, Length=488, Percent_Identity=23.155737704918, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1789966, Length=469, Percent_Identity=23.454157782516, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787551, Length=493, Percent_Identity=22.1095334685598, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=23.7903225806452, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61196; Mature: 61196

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKA
CCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
TDGESMNVMRNVFEGLYAMGEDNKPVPGVAESVDISPDKTKYTFHLRDSKWSNGTPVTAK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
DFAFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPIDQLGVKAVDDKTLEVQLDRPVP
HHHHHHHHCCCCCCHHCEEEEEEEECCHHHHHHHCCCHHHHCCEEECCCEEEEEECCCCC
YFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
CEEEHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECEEEECCCCCCCCEEECCCCCCCC
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKSDPNFKERAEVGIQFLR
CEEEEEEECCEEEEECCCCEEEEECCCCCCEEEEEHHHHHHHCCCCCHHHHHHHCEEEEE
LNQKNETLKNQHARLAINGAMNKKAYVETILNNGAVPAEGMVPAKFAKSPEGNDFRKENG
ECCCCHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHCCC
NLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKKTGEYLKGELEKNLDGLTVNL
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
KPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
CCCCHHHHEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCHHHHHHHH
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEE
WTEVTK
EEECCC
>Mature Secondary Structure
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKA
CCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
TDGESMNVMRNVFEGLYAMGEDNKPVPGVAESVDISPDKTKYTFHLRDSKWSNGTPVTAK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
DFAFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPIDQLGVKAVDDKTLEVQLDRPVP
HHHHHHHHCCCCCCHHCEEEEEEEECCHHHHHHHCCCHHHHCCEEECCCEEEEEECCCCC
YFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
CEEEHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECEEEECCCCCCCCEEECCCCCCCC
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKSDPNFKERAEVGIQFLR
CEEEEEEECCEEEEECCCCEEEEECCCCCCEEEEEHHHHHHHCCCCCHHHHHHHCEEEEE
LNQKNETLKNQHARLAINGAMNKKAYVETILNNGAVPAEGMVPAKFAKSPEGNDFRKENG
ECCCCHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHCCC
NLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKKTGEYLKGELEKNLDGLTVNL
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
KPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
CCCCHHHHEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCHHHHHHHH
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEE
WTEVTK
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]