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The map label for this gene is ptsG

Identifier: 21672620

GI number: 21672620

Start: 389597

End: 391030

Strand: Direct

Name: ptsG

Synonym: BUsg344

Alternate gene names: 21672620

Gene position: 389597-391030 (Clockwise)

Preceding gene: 21672619

Following gene: 21672621

Centisome position: 60.74

GC content: 29.57

Gene sequence:

>1434_bases
ATGTTTAAAAATGTATTTTCAAGCCTTCAAAAGGTTGGTAAATCACTGATGTTACCTGTTTCAGTACTTCCAATTGCGGG
AATACTTCTTGGTATAGGATCAGCTCATTTTACTTTAATACCGGAAATAATTTCTCAAATTATGGCACAAACAGGGGGCT
CTATTTTTTCTAATATGCCATTAATTTTTGCAATTGGTGTAGCTCTTGGATTTAGTAATAATGATGGTGTTGCAGCATTA
GCTGCTGTTGTTGCTTACAGTATATTAATTCAAACACTATCTGCAGTAGAACTAAATATATTAAATACAGATGCTAATAC
AATAAAAAATAAAAATTTTTCTGATATTGGTATATTAGGAGGAATTATAGCAGGAGCCATTTCAGCATATATGTTTAACA
AATTTTATAAAATTCAGTTACCTGAATATTTAGGTTTTTTTGCTGGAAAAAGATTTGTTCCTATTATTTCAGGACTATTT
GCAATATTTGTAGGATTAATATTATCTCTTATTTGGCCTAGTATTGGCAATAAAATACAAATTTTTTCCGAATGGGCTGC
TTATCAAAATCCTATTATTGCTTTTTCTTTGTACGGTTTAGTAGAAAGAGCATTAGTACCTTTTGGTCTACATCATATAT
GGAATGTTCCATTCCAAATGCAAATTGGAGAATATAAGAATTCTATAGGGCAAATTTTTCATGGAGATATTGCAAGATAT
ATGGCAGGTGATACAACAGCTGGGAATTTATCAGGTGGATTTATTTTCAAAATGTATGGACTTCCAGGAGCAGCTTTAGC
AATTTGGCATACAGCTAAAAAAGAAAATAGAAAAAAAATAGGTAGTATTATGATTTCTGCAGCTTTGACAGCTTTTTTAA
CAGGAATTACTGAACCAATTGAGTTTTCTTTCATATTAGTTGCTCCAATATTATATATTATTCACGCTATTTTAGCAGGA
TTGTCTTTTCCATTATGTATTTTTTTAAATATGCGTGCTGGAACAAGTTTTTCTCATGGATTTATAGATTTTATAGTATT
AAGTGGGCATAGTCATAAAATATTTCTTTTCCCAATTGTTGGAATTTGCTATGGTCTTTTATATTATAGTATATTTTATT
TTTTGATAACAACATTTAATTTAAAAACACCTGGACGAGAAGAAAATAAAAACACTGTTTTTTTTAGAAATAATATAGAA
ATAGCACCGTATATTGTTGAAGCATTGGGTGGAAAAAATAATATTAAAAATTTAGATGCATGTATTACTAGATTACGTAT
TACAGTCTCAGAAATATCAAAAGTTAACGAAGAGAATCTAAAAAATCTTGGGGCAGCAGGTGTGGTTATTTCAGGATCTG
GGGTGCAAGCTGTCTTCGGTACTAGATCAGAAAATATAAAAACTGCAATAGATGAATATATAAATAATATATAA

Upstream 100 bases:

>100_bases
CACTACAAATAATTTTTTTACGCTATTTAACTTAAATTTTTAATAAAAATATATTATTTAATTTATTTGACATTTTAGAT
ATACCTAGGAGTTTTTAAAT

Downstream 100 bases:

>100_bases
AAAAAAGGGTGAGTAAAAATTTAACTCGCCCTAGTATTTATAAAATTTAATATTAATTTAAATTATACAAAAGAATATTT
TATGAATAATAAAGATTTAA

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMPLIFAIGVALGFSNNDGVAAL
AAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILGGIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLF
AIFVGLILSLIWPSIGNKIQIFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARY
MAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPIEFSFILVAPILYIIHAILAG
LSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIVGICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIE
IAPYIVEALGGKNNIKNLDACITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI

Sequences:

>Translated_477_residues
MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMPLIFAIGVALGFSNNDGVAAL
AAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILGGIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLF
AIFVGLILSLIWPSIGNKIQIFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARY
MAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPIEFSFILVAPILYIIHAILAG
LSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIVGICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIE
IAPYIVEALGGKNNIKNLDACITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI
>Mature_477_residues
MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMPLIFAIGVALGFSNNDGVAAL
AAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILGGIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLF
AIFVGLILSLIWPSIGNKIQIFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARY
MAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPIEFSFILVAPILYIIHAILAG
LSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIVGICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIE
IAPYIVEALGGKNNIKNLDACITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain

Homologues:

Organism=Escherichia coli, GI1787343, Length=476, Percent_Identity=70.3781512605042, Blast_Score=718, Evalue=0.0,
Organism=Escherichia coli, GI1786894, Length=486, Percent_Identity=38.2716049382716, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1787908, Length=527, Percent_Identity=37.1916508538899, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTGCB_BUCAP (Q8K9J0)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660687.1
- ProteinModelPortal:   Q8K9J0
- SMR:   Q8K9J0
- EnsemblBacteria:   EBBUCT00000000486
- GeneID:   1005590
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg344
- GeneTree:   EBGT00050000007830
- HOGENOM:   HBG571563
- OMA:   KIQIFSE
- ProtClustDB:   PRK11089
- BioCyc:   BAPH198804:BUSG344-MONOMER
- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299
- Gene3D:   G3DSA:3.30.1360.60
- TIGRFAMs:   TIGR00826
- TIGRFAMs:   TIGR02002

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC; SSF55604 PTS_EIIB

EC number: =2.7.1.69

Molecular weight: Translated: 51942; Mature: 51942

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS51098 PTS_EIIB_TYPE_1; PS01035 PTS_EIIB_TYPE_1_CYS; PS51103 PTS_EIIC_TYPE_1

Important sites: ACT_SITE 421-421

Signals:

None

Transmembrane regions:

HASH(0xb0e0530)-; HASH(0xb3a6688)-; HASH(0xc587594)-; HASH(0x4046a9a0)-; HASH(0xc35905c)-; HASH(0xc413404)-; HASH(0xbd7ba6c)-; HASH(0xbc1ee20)-; HASH(0x959d0ac)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHCCH
LIFAIGVALGFSNNDGVAALAAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCCCHHHHHH
GIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLFAIFVGLILSLIWPSIGNKIQ
HHHHHHHHHHHHHHHHEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARY
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHH
MAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPI
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EFSFILVAPILYIIHAILAGLSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEHHHH
GICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIEIAPYIVEALGGKNNIKNLDA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHH
CITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI
HHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCH
>Mature Secondary Structure
MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHCCH
LIFAIGVALGFSNNDGVAALAAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHCCCCCCHHHHHH
GIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLFAIFVGLILSLIWPSIGNKIQ
HHHHHHHHHHHHHHHHEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARY
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHH
MAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPI
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EFSFILVAPILYIIHAILAGLSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEHHHH
GICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIEIAPYIVEALGGKNNIKNLDA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHH
CITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI
HHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438