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The map label for this gene is fabZ

Identifier: 21672513

GI number: 21672513

Start: 264145

End: 264603

Strand: Direct

Name: fabZ

Synonym: BUsg232

Alternate gene names: 21672513

Gene position: 264145-264603 (Clockwise)

Preceding gene: 21672512

Following gene: 21672514

Centisome position: 41.18

GC content: 23.97

Gene sequence:

>459_bases
TTGAATTCTGATGAATATATTTTTAATATTAAAGATATTTTAAATATTTTACCGCATCGCTATCCTTTTTTACTTATTGA
TCGGATTTTAGATTTTAAAGCATTTCAATATTTAAAAGCACTTAAAAACTGTACTGTAAATGAACCTTTTTTTCAAGGTC
ATTTTATAAAAGAACCTGTTTTTCCTGGTGTTTTAATGATTGAAGCTATGAGTCAAGCGGCTGCTGTTTTGATTTTTAAA
AGCATAGGTAAATTGAATATTAATCAGTTGTACTACTTCGTAGGTATTGAGAATACGCGATTTAAAAAAATTGTAGTGCC
TGGTGATCAAATATTTATTGAAGTAATATACCTAAAGTCTAAAAAAAACTTTATAAAATTTAAAATTTTTGCCATAGTGA
ATAAAAAGAATGTTTGTAAATCTACAATAATTTTTTATAAAAAAAATATCTTTAATTGA

Upstream 100 bases:

>100_bases
ATTTAACTTTGGAAAAAATTGGTAATTAGAATAAAGTTTAATGTTTAGTATTAATTTTATAAAAAATAAAAATATTGTTT
TTTTTAAATAGGAAAAAATT

Downstream 100 bases:

>100_bases
AAAGATGTTGATATAATTTTTAGGAAATTCAATGAATTTAGAAGAATTTGTACATCTTCACGTACACAGCGATTATTCAA
TTGTTGATGGATTGTCTAAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNSDEYIFNIKDILNILPHRYPFLLIDRILDFKAFQYLKALKNCTVNEPFFQGHFIKEPVFPGVLMIEAMSQAAAVLIFK
SIGKLNINQLYYFVGIENTRFKKIVVPGDQIFIEVIYLKSKKNFIKFKIFAIVNKKNVCKSTIIFYKKNIFN

Sequences:

>Translated_152_residues
MNSDEYIFNIKDILNILPHRYPFLLIDRILDFKAFQYLKALKNCTVNEPFFQGHFIKEPVFPGVLMIEAMSQAAAVLIFK
SIGKLNINQLYYFVGIENTRFKKIVVPGDQIFIEVIYLKSKKNFIKFKIFAIVNKKNVCKSTIIFYKKNIFN
>Mature_152_residues
MNSDEYIFNIKDILNILPHRYPFLLIDRILDFKAFQYLKALKNCTVNEPFFQGHFIKEPVFPGVLMIEAMSQAAAVLIFK
SIGKLNINQLYYFVGIENTRFKKIVVPGDQIFIEVIYLKSKKNFIKFKIFAIVNKKNVCKSTIIFYKKNIFN

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=149, Percent_Identity=50.3355704697987, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_BUCAP (Q8K9S4)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660580.1
- ProteinModelPortal:   Q8K9S4
- SMR:   Q8K9S4
- EnsemblBacteria:   EBBUCT00000000170
- GeneID:   1005432
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg232
- GeneTree:   EBGT00050000007728
- HOGENOM:   HBG433282
- OMA:   NVSANES
- ProtClustDB:   PRK00006
- BioCyc:   BAPH198804:BUSG232-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17858; Mature: 17858

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSDEYIFNIKDILNILPHRYPFLLIDRILDFKAFQYLKALKNCTVNEPFFQGHFIKEPV
CCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLMIEAMSQAAAVLIFKSIGKLNINQLYYFVGIENTRFKKIVVPGDQIFIEVIYLKS
CCHHHHHHHHHHHHHHHHHHHCCCCEECEEEEEEEECCCCEEEEEECCCEEEEEEEEEEC
KKNFIKFKIFAIVNKKNVCKSTIIFYKKNIFN
CCCEEEEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSDEYIFNIKDILNILPHRYPFLLIDRILDFKAFQYLKALKNCTVNEPFFQGHFIKEPV
CCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLMIEAMSQAAAVLIFKSIGKLNINQLYYFVGIENTRFKKIVVPGDQIFIEVIYLKS
CCHHHHHHHHHHHHHHHHHHHCCCCEECEEEEEEEECCCCEEEEEECCCEEEEEEEEEEC
KKNFIKFKIFAIVNKKNVCKSTIIFYKKNIFN
CCCEEEEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438