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The map label for this gene is groES

Identifier: 21672312

GI number: 21672312

Start: 18275

End: 18565

Strand: Direct

Name: groES

Synonym: BUsg018

Alternate gene names: 21672312

Gene position: 18275-18565 (Clockwise)

Preceding gene: 21672311

Following gene: 21672313

Centisome position: 2.85

GC content: 34.36

Gene sequence:

>291_bases
ATGAAAATTCGTCCATTGCATGATCGCGTGCTTGTAAAACGTAACGAAGCAGAATTAAAGTCTGCAGGTGGTATTGTACT
TACAGGTTCTGCTGCAGCAAAATCTACTCGCGGAACGATTACAGCAGTTGGTAATGGTCGTGTTCTAGATAATGGTCAAA
TTAAACCATTAGATGTTAAAGTTGGTGATGTTGTAATTTTTAATGAAGGTTATGGTGCAAAAACAGAAAAAATTGATAAT
GAAGAACTATTAATTTTAAATGAGAGTGACATTTTAGCAATTGTTGAATAG

Upstream 100 bases:

>100_bases
AGTAAGCATCCCTATATTTAATATATAAAGAAAGTATTAAATAAAAAAATAATTTTTTTTAATATAATTAAGCAAAATTA
TTCACAGGAGTATCGCTAAT

Downstream 100 bases:

>100_bases
TAAACTAAACCATATATGCTATATCCATAAAACAATATATTTAAGGAAATGTCAAAAATGGGCGCTAAAGATGTAAAATT
TGGTAATGAAGCTCGAATTA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVKVGDVVIFNEGYGAKTEKIDN
EELLILNESDILAIVE

Sequences:

>Translated_96_residues
MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVKVGDVVIFNEGYGAKTEKIDN
EELLILNESDILAIVE
>Mature_96_residues
MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVKVGDVVIFNEGYGAKTEKIDN
EELLILNESDILAIVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=80.2083333333333, Blast_Score=160, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=38.0434782608696, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=45.360824742268, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_BUCAP (Q59176)

Other databases:

- EMBL:   D85628
- EMBL:   AF008210
- EMBL:   AE013218
- RefSeq:   NP_660379.1
- ProteinModelPortal:   Q59176
- SMR:   Q59176
- EnsemblBacteria:   EBBUCT00000000149
- GeneID:   1005834
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg018
- GeneTree:   EBGT00050000007913
- HOGENOM:   HBG703377
- OMA:   SEKIDGE
- ProtClustDB:   PRK00364
- BioCyc:   BAPH198804:BUSG018-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10268; Mature: 10268

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVK
CCCCCCCCEEEEECCCCCHHCCCCEEEECCCCCCCCCCEEEECCCCEEECCCCEEEEEEE
VGDVVIFNEGYGAKTEKIDNEELLILNESDILAIVE
ECCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEC
>Mature Secondary Structure
MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVK
CCCCCCCCEEEEECCCCCHHCCCCEEEECCCCCCCCCCEEEECCCCEEECCCCEEEEEEE
VGDVVIFNEGYGAKTEKIDNEELLILNESDILAIVE
ECCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9516544; 12089438