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The map label for this gene is rnpA

Identifier: 21672308

GI number: 21672308

Start: 14337

End: 14681

Strand: Direct

Name: rnpA

Synonym: BUsg014

Alternate gene names: 21672308

Gene position: 14337-14681 (Clockwise)

Preceding gene: 21672307

Following gene: 21672309

Centisome position: 2.24

GC content: 22.32

Gene sequence:

>345_bases
GTGTTAAATTATTTTTTTAAAAAAAAATCGAAATTGTTAAAATCTACAAATTTTCAATATGTTTTTAGTAATCCCTGTAA
TAAAAATACTTTTCACATAAACATATTAGGACGTTCTAATTTATTAGGACATCCTAGATTAGGTCTTAGTATATCGCGTA
AAAATATTAAACATGCATATAGACGTAATAAAATTAAACGATTAATTCGAGAAACTTTTCGTTTATTACAACATAGATTA
ATCTCAATGGATTTCGTTGTTATAGCAAAGAAAAATATTGTTTATTTAAATAATAAAAAAATAGTAAATATATTGGAGTA
TATATGGTCAAACTATCAACGATAG

Upstream 100 bases:

>100_bases
ACTCGGATGGCAACTAAAAATGGGCGTTATATTTTGTCACGTAGACGTGCAAAATTGAGAACGCGTTTAACTGTTTCTAG
TAAATAATAGGTTGAATATA

Downstream 100 bases:

>100_bases
TTGTTTTTTGTTTAACTTTTTTCGTTTCGATTTATCAAAATTATATTAGTTTTTTTATGCCTTCAAATTGTCGTTTTTAT
CCTACTTGCTCAACATATAT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MLNYFFKKKSKLLKSTNFQYVFSNPCNKNTFHINILGRSNLLGHPRLGLSISRKNIKHAYRRNKIKRLIRETFRLLQHRL
ISMDFVVIAKKNIVYLNNKKIVNILEYIWSNYQR

Sequences:

>Translated_114_residues
MLNYFFKKKSKLLKSTNFQYVFSNPCNKNTFHINILGRSNLLGHPRLGLSISRKNIKHAYRRNKIKRLIRETFRLLQHRL
ISMDFVVIAKKNIVYLNNKKIVNILEYIWSNYQR
>Mature_114_residues
MLNYFFKKKSKLLKSTNFQYVFSNPCNKNTFHINILGRSNLLGHPRLGLSISRKNIKHAYRRNKIKRLIRETFRLLQHRL
ISMDFVVIAKKNIVYLNNKKIVNILEYIWSNYQR

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=114, Percent_Identity=46.4912280701754, Blast_Score=121, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_BUCAP (P29433)

Other databases:

- EMBL:   M80817
- EMBL:   AF008210
- EMBL:   AE013218
- PIR:   JC1155
- RefSeq:   NP_660375.1
- ProteinModelPortal:   P29433
- SMR:   P29433
- EnsemblBacteria:   EBBUCT00000000282
- GeneID:   1005830
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg014
- GeneTree:   EBGT00050000008201
- HOGENOM:   HBG728160
- OMA:   PRIGLAI
- ProtClustDB:   PRK01732
- BioCyc:   BAPH198804:BUSG014-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13785; Mature: 13785

Theoretical pI: Translated: 11.60; Mature: 11.60

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYFFKKKSKLLKSTNFQYVFSNPCNKNTFHINILGRSNLLGHPRLGLSISRKNIKHAY
CCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEECHHHHHHHH
RRNKIKRLIRETFRLLQHRLISMDFVVIAKKNIVYLNNKKIVNILEYIWSNYQR
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNYFFKKKSKLLKSTNFQYVFSNPCNKNTFHINILGRSNLLGHPRLGLSISRKNIKHAY
CCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEECHHHHHHHH
RRNKIKRLIRETFRLLQHRLISMDFVVIAKKNIVYLNNKKIVNILEYIWSNYQR
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1572539; 9516544; 12089438