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The map label for this gene is kdgR [H]

Identifier: 21244908

GI number: 21244908

Start: 4929315

End: 4930064

Strand: Direct

Name: kdgR [H]

Synonym: XAC4191

Alternate gene names: 21244908

Gene position: 4929315-4930064 (Clockwise)

Preceding gene: 21244905

Following gene: 21244909

Centisome position: 95.24

GC content: 68.53

Gene sequence:

>750_bases
ATGAGCACCGAACCCGCCAAGTACCGCGCGCCCGCCCTGGACAAGGGCCTGGACATCCTGGAGCTGCTCGCTCGCCAGGC
GCAGCCGATGAGCATGGGCGCAATCTCGCAGGGCATCGGCCGCTCGCGCGGGGAGATCTTCCGCATGCTGCAGGTGCTGG
AGGAGCGCGGCTACCTCACGCGCGATGGAGAAGGCGACTACGTGCTGACCAACCGCCTGTTCATGCTCGGCATGCAGCAG
CCGCAGGTGCAGAGCATCAGCGAGGCCGCGTTGCCGGTGATGCGGCGCTTGTCCGATGCGATCTACCAGCCCTGCCACCT
GGTGGCGCCATCCGGCGACCAGATCGTGGTGATCGCGCAAATGGACGTGCCCAGCGACCTGGGCCTGGTGGTACGCCCGG
GGCATCGTCGCCCGTTGACGCATTCCAGCTCCGGGCTGGTGCTGTTCGCCTTCCAACAGCCGGAGGTGCAGGCGCGCTGG
CTGGACATGCTCGAGGCCAGCGAAGTGCCGTTCGAGCGCGCGCAGTTCCTGGCCGCCGCCGGGCAGGCGCGCCGCGATGG
TTATGCCATGCAGCCCAGCGAAGCGGTGGTGGGCGTGGTCGATCTCACTGCACCGATCCTGCAGCGCGGCAGCGCCACCT
ACACGCTCACGGTGCCCTTCATCGAACGGCGCCCTGCGCTGGTGAGTCCGCAAGCGGCGTTACAGGCCCTGTGCGCGGCA
ACCGCCGAGATTTCCAGCGCGCTGCACTAG

Upstream 100 bases:

>100_bases
ATAAAATCTTTGTTTATATTTGCACTGACACGCGCCACCTGACCCCGCCCCGCGTTGCCTGTACCCTGGCGCGCCGCACC
TTGCCTGGACCTGCAAACGG

Downstream 100 bases:

>100_bases
CGACGTGCGCGACCGGCGCACGCGCGCCATCGCCTGCCACGCGCATTTCCAGGCGCCCCACTCCTGCGCGACGCCGCATC
GCCCCTGCGCGCCGCACGTC

Product: transcriptional regulator KdgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSTEPAKYRAPALDKGLDILELLARQAQPMSMGAISQGIGRSRGEIFRMLQVLEERGYLTRDGEGDYVLTNRLFMLGMQQ
PQVQSISEAALPVMRRLSDAIYQPCHLVAPSGDQIVVIAQMDVPSDLGLVVRPGHRRPLTHSSSGLVLFAFQQPEVQARW
LDMLEASEVPFERAQFLAAAGQARRDGYAMQPSEAVVGVVDLTAPILQRGSATYTLTVPFIERRPALVSPQAALQALCAA
TAEISSALH

Sequences:

>Translated_249_residues
MSTEPAKYRAPALDKGLDILELLARQAQPMSMGAISQGIGRSRGEIFRMLQVLEERGYLTRDGEGDYVLTNRLFMLGMQQ
PQVQSISEAALPVMRRLSDAIYQPCHLVAPSGDQIVVIAQMDVPSDLGLVVRPGHRRPLTHSSSGLVLFAFQQPEVQARW
LDMLEASEVPFERAQFLAAAGQARRDGYAMQPSEAVVGVVDLTAPILQRGSATYTLTVPFIERRPALVSPQAALQALCAA
TAEISSALH
>Mature_248_residues
STEPAKYRAPALDKGLDILELLARQAQPMSMGAISQGIGRSRGEIFRMLQVLEERGYLTRDGEGDYVLTNRLFMLGMQQP
QVQSISEAALPVMRRLSDAIYQPCHLVAPSGDQIVVIAQMDVPSDLGLVVRPGHRRPLTHSSSGLVLFAFQQPEVQARWL
DMLEASEVPFERAQFLAAAGQARRDGYAMQPSEAVVGVVDLTAPILQRGSATYTLTVPFIERRPALVSPQAALQALCAAT
AEISSALH

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=231, Percent_Identity=28.1385281385281, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27123; Mature: 26991

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEPAKYRAPALDKGLDILELLARQAQPMSMGAISQGIGRSRGEIFRMLQVLEERGYLT
CCCCCCCCCCCCHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
RDGEGDYVLTNRLFMLGMQQPQVQSISEAALPVMRRLSDAIYQPCHLVAPSGDQIVVIAQ
ECCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEE
MDVPSDLGLVVRPGHRRPLTHSSSGLVLFAFQQPEVQARWLDMLEASEVPFERAQFLAAA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHH
GQARRDGYAMQPSEAVVGVVDLTAPILQRGSATYTLTVPFIERRPALVSPQAALQALCAA
CCHHCCCCCCCCCHHEEEHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHH
TAEISSALH
HHHHHHHCC
>Mature Secondary Structure 
STEPAKYRAPALDKGLDILELLARQAQPMSMGAISQGIGRSRGEIFRMLQVLEERGYLT
CCCCCCCCCCCHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
RDGEGDYVLTNRLFMLGMQQPQVQSISEAALPVMRRLSDAIYQPCHLVAPSGDQIVVIAQ
ECCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEE
MDVPSDLGLVVRPGHRRPLTHSSSGLVLFAFQQPEVQARWLDMLEASEVPFERAQFLAAA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHH
GQARRDGYAMQPSEAVVGVVDLTAPILQRGSATYTLTVPFIERRPALVSPQAALQALCAA
CCHHCCCCCCCCCHHEEEHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHH
TAEISSALH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]