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The map label for this gene is motA [H]

Identifier: 21244418

GI number: 21244418

Start: 4369130

End: 4369984

Strand: Direct

Name: motA [H]

Synonym: XAC3693

Alternate gene names: 21244418

Gene position: 4369130-4369984 (Clockwise)

Preceding gene: 21244417

Following gene: 21244419

Centisome position: 84.42

GC content: 62.57

Gene sequence:

>855_bases
ATGCTCATCATCGTTGGCTTCATCGTCGTCATCGTCAGCGTCCTCGGCGGCTACGTGCTGTCGCACGGAAAGCTGGGCGC
GCTGTGGCAGCCGTACGAGCTGATGATCATCGGTGGCGCGGCATTGGGCGCCTTCCTGGTCAGCACGCCGGGCAAGATCG
TCAAGGAAACCCTCAGCGGCATCATGGGCGTGTTCAAGGGCCCGCAGTACAAGTCCGACGACTACAAGGACACCCTGAGC
CTGATCTACGAGCTGCTGAACAAGGCGCGCCGCGATGGCTTCATGGCGTTGGAAGACCATGTCGAAAAGCCGCAGGACAG
CACCATCTTCGGCAATTACCCCAAGGTGGTGGCCGACCATCACCTGCTGGACTTCATCACCGACTGCCTGCGCCTGATGA
TCGGCAGCAACATCGAGCCGCACGAGCTGGAACCGCTGCTCGAACTGGAACTGGAAAAACACCATCACGAAGCTCTGGCA
CCTTCGCATGCGCTGAGCAAGGTGTCCGACGGCCTGCCCGGCTTCGGCATCGTGGCGGCGGTGCTCGGCATCGTGATCAC
CATGGGCTCGATCGGCGGGCCAATCGAAGAGATCGGCCACCACGTCGGCGCCGCGCTGGTCGGCACCTTCCTCGGCATCC
TGCTGGCCTACGGCTTCGTCTCGCCATTGTCGGCGGCGATGGAAGCGCGTGCCGAGCAGGACGGGCGCATCTACGAAGCG
GTCAAGACCGCGCTGCTGGCGTGCCTGCGTGGCTACAACCCGAAGATTGCGCTGGAATTCGCGCGCAAGACCCTGCCCTC
CAATGTGCGTCCGAGCTTCGGCGATTTCGAAACGCACCTGAAGACGATCAAGTAG

Upstream 100 bases:

>100_bases
TAGACATTCAGCGACAACGCACGTCTTCACGCCGTGCGCTTCAAGAATCGGCTGCGCAAGCCGAAACCACTAGCAACCCC
AGTTTGCTTCCGGCTGCGCC

Downstream 100 bases:

>100_bases
GGCCACGGTCATGGCCGAGGCCAAATCCACCGTCATCATCAGACGGGTCAAGAAGGTACAGGGCGGCGGCCATCATGGCG
GCGCCTGGAAGGTGGCTTTT

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLIIVGFIVVIVSVLGGYVLSHGKLGALWQPYELMIIGGAALGAFLVSTPGKIVKETLSGIMGVFKGPQYKSDDYKDTLS
LIYELLNKARRDGFMALEDHVEKPQDSTIFGNYPKVVADHHLLDFITDCLRLMIGSNIEPHELEPLLELELEKHHHEALA
PSHALSKVSDGLPGFGIVAAVLGIVITMGSIGGPIEEIGHHVGAALVGTFLGILLAYGFVSPLSAAMEARAEQDGRIYEA
VKTALLACLRGYNPKIALEFARKTLPSNVRPSFGDFETHLKTIK

Sequences:

>Translated_284_residues
MLIIVGFIVVIVSVLGGYVLSHGKLGALWQPYELMIIGGAALGAFLVSTPGKIVKETLSGIMGVFKGPQYKSDDYKDTLS
LIYELLNKARRDGFMALEDHVEKPQDSTIFGNYPKVVADHHLLDFITDCLRLMIGSNIEPHELEPLLELELEKHHHEALA
PSHALSKVSDGLPGFGIVAAVLGIVITMGSIGGPIEEIGHHVGAALVGTFLGILLAYGFVSPLSAAMEARAEQDGRIYEA
VKTALLACLRGYNPKIALEFARKTLPSNVRPSFGDFETHLKTIK
>Mature_284_residues
MLIIVGFIVVIVSVLGGYVLSHGKLGALWQPYELMIIGGAALGAFLVSTPGKIVKETLSGIMGVFKGPQYKSDDYKDTLS
LIYELLNKARRDGFMALEDHVEKPQDSTIFGNYPKVVADHHLLDFITDCLRLMIGSNIEPHELEPLLELELEKHHHEALA
PSHALSKVSDGLPGFGIVAAVLGIVITMGSIGGPIEEIGHHVGAALVGTFLGILLAYGFVSPLSAAMEARAEQDGRIYEA
VKTALLACLRGYNPKIALEFARKTLPSNVRPSFGDFETHLKTIK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=46.1267605633803, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30694; Mature: 30694

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGFIVVIVSVLGGYVLSHGKLGALWQPYELMIIGGAALGAFLVSTPGKIVKETLSG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHH
IMGVFKGPQYKSDDYKDTLSLIYELLNKARRDGFMALEDHVEKPQDSTIFGNYPKVVADH
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCHHHHHH
HLLDFITDCLRLMIGSNIEPHELEPLLELELEKHHHEALAPSHALSKVSDGLPGFGIVAA
HHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHH
VLGIVITMGSIGGPIEEIGHHVGAALVGTFLGILLAYGFVSPLSAAMEARAEQDGRIYEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VKTALLACLRGYNPKIALEFARKTLPSNVRPSFGDFETHLKTIK
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MLIIVGFIVVIVSVLGGYVLSHGKLGALWQPYELMIIGGAALGAFLVSTPGKIVKETLSG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHH
IMGVFKGPQYKSDDYKDTLSLIYELLNKARRDGFMALEDHVEKPQDSTIFGNYPKVVADH
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCHHHHHH
HLLDFITDCLRLMIGSNIEPHELEPLLELELEKHHHEALAPSHALSKVSDGLPGFGIVAA
HHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHH
VLGIVITMGSIGGPIEEIGHHVGAALVGTFLGILLAYGFVSPLSAAMEARAEQDGRIYEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VKTALLACLRGYNPKIALEFARKTLPSNVRPSFGDFETHLKTIK
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]