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The map label for this gene is ucpA [C]

Identifier: 21244316

GI number: 21244316

Start: 4257944

End: 4258672

Strand: Direct

Name: ucpA [C]

Synonym: XAC3591

Alternate gene names: 21244316

Gene position: 4257944-4258672 (Clockwise)

Preceding gene: 77748732

Following gene: 21244317

Centisome position: 82.27

GC content: 62.69

Gene sequence:

>729_bases
ATGCAACGCGTCCTTATTATCGGGGCCACCTCGGCCATCGCCGAAGCAACCGCCCGACGCTACGCCGCACGCGGTGCGGC
CATCCACCTGCTCGGGCGCCAAGCCCCGCGCCTTGACACAATTTCGGCCGACCTCACGACCCGCGGCGCGCGAAGCAGCT
TTGGCGTGCTGGATGTCAACGACAATGCACGTCATGGCGAGGTCCTGGATGCAGCCTGGGCTGCATTGGGCGGTGTCGAC
GTCGTATTGATCGCACATGGCACGCTGCCGGATCAGGCTGCGTGTGACGCATCGGTCGAACTGTCGCTGCGCGAATTCGC
CACCAACGGCACCTCCACGATTGCCCTGTGCGCAGCGATTGTGCCGCGACTGACGTCGGGCGCCACGCTAGCAGGCATTT
CTTCTGTGGCAGGAGACCGCGGCCGAGCCAGCAACTACCTTTATGGAAGCGCCAAGGCCGCTGTGACCGCTTACCTGAGC
GGCCTGGGACAGCGCCTGCGCCCACAAGGCATCAACGTCCTCACGATCAAGCCGGGCTTCGTCGACACCCCCATGACCGC
GGCGTTCAAAAAGGGCGCTCTGTGGGCAAAGCCGGACCAGATTGCCAAGGGAATCCTCAGTGCAGTGGACAAGCGCCGCT
CTGTGGCTTACCTGCCTGGTTTCTGGTGGGCAATCATGCTTGTGATCAAATCCATTCCCGAAGTCGTTTTCCGCAAAGTC
AAGCTCTGA

Upstream 100 bases:

>100_bases
CGCAGTCGTTTCAGCGTGCCTATGGCCGCTGGCGCGAGTTCGGCAGCTATCTCGATCCACGTTTTTCTTCCGGCTTCTGG
CGCCGGGTCACGGAGTAGAC

Downstream 100 bases:

>100_bases
CATGATCGGTCGACATGCCATGTTCTGCATCGCGGCACCCTTGTCCGAGCAGAACAACCTAGCAGGAATTTTTGACAGGT
CCCATAGGACCAGAGTCTCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQRVLIIGATSAIAEATARRYAARGAAIHLLGRQAPRLDTISADLTTRGARSSFGVLDVNDNARHGEVLDAAWAALGGVD
VVLIAHGTLPDQAACDASVELSLREFATNGTSTIALCAAIVPRLTSGATLAGISSVAGDRGRASNYLYGSAKAAVTAYLS
GLGQRLRPQGINVLTIKPGFVDTPMTAAFKKGALWAKPDQIAKGILSAVDKRRSVAYLPGFWWAIMLVIKSIPEVVFRKV
KL

Sequences:

>Translated_242_residues
MQRVLIIGATSAIAEATARRYAARGAAIHLLGRQAPRLDTISADLTTRGARSSFGVLDVNDNARHGEVLDAAWAALGGVD
VVLIAHGTLPDQAACDASVELSLREFATNGTSTIALCAAIVPRLTSGATLAGISSVAGDRGRASNYLYGSAKAAVTAYLS
GLGQRLRPQGINVLTIKPGFVDTPMTAAFKKGALWAKPDQIAKGILSAVDKRRSVAYLPGFWWAIMLVIKSIPEVVFRKV
KL
>Mature_242_residues
MQRVLIIGATSAIAEATARRYAARGAAIHLLGRQAPRLDTISADLTTRGARSSFGVLDVNDNARHGEVLDAAWAALGGVD
VVLIAHGTLPDQAACDASVELSLREFATNGTSTIALCAAIVPRLTSGATLAGISSVAGDRGRASNYLYGSAKAAVTAYLS
GLGQRLRPQGINVLTIKPGFVDTPMTAAFKKGALWAKPDQIAKGILSAVDKRRSVAYLPGFWWAIMLVIKSIPEVVFRKV
KL

Specific function: May be involved in the biosynthesis of a heptaene-type antibiotic [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17559104, Length=223, Percent_Identity=28.6995515695067, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=208, Percent_Identity=29.8076923076923, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI23397609, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25409; Mature: 25409

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVLIIGATSAIAEATARRYAARGAAIHLLGRQAPRLDTISADLTTRGARSSFGVLDVN
CCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCEEECC
DNARHGEVLDAAWAALGGVDVVLIAHGTLPDQAACDASVELSLREFATNGTSTIALCAAI
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VPRLTSGATLAGISSVAGDRGRASNYLYGSAKAAVTAYLSGLGQRLRPQGINVLTIKPGF
HHHHCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
VDTPMTAAFKKGALWAKPDQIAKGILSAVDKRRSVAYLPGFWWAIMLVIKSIPEVVFRKV
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHC
KL
CC
>Mature Secondary Structure
MQRVLIIGATSAIAEATARRYAARGAAIHLLGRQAPRLDTISADLTTRGARSSFGVLDVN
CCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCEEECC
DNARHGEVLDAAWAALGGVDVVLIAHGTLPDQAACDASVELSLREFATNGTSTIALCAAI
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VPRLTSGATLAGISSVAGDRGRASNYLYGSAKAAVTAYLSGLGQRLRPQGINVLTIKPGF
HHHHCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
VDTPMTAAFKKGALWAKPDQIAKGILSAVDKRRSVAYLPGFWWAIMLVIKSIPEVVFRKV
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHC
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406267 [H]