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The map label for this gene is kdtA [H]

Identifier: 21244189

GI number: 21244189

Start: 4089200

End: 4090516

Strand: Reverse

Name: kdtA [H]

Synonym: XAC3464

Alternate gene names: 21244189

Gene position: 4090516-4089200 (Counterclockwise)

Preceding gene: 21244191

Following gene: 77748715

Centisome position: 79.04

GC content: 66.44

Gene sequence:

>1317_bases
ATGCGGAAAGATCCGATCGAATGGCTGTTGCGCGGGCTGTACTCGGCGCTGCTCTACTTGTTGTTGCCGGTCACGGTGTA
CCACCTGGTATGGCGTGGCTTTCGCGTGCGCGAATACTTCAATCGCTGGAACGAGCGCTATGCGTCCTACACGCATGCCT
GCGGGCGGCCACGGGTATGGGTGCACGCGGTGTCGGTGGGCGAGGTCAACGCGGCCGCGCCGCTGGTCAACGCGCTACGT
GCGCAGCGCCCGGATATCCGTTGGGTCATCACCACCATCACCCCTACCGGCTCCGAGCGCGTGCGCGCGCTGTGGGGCGA
TGCGGTGGACCATGTGTACCTGCCCTACGACGTACCCGGCAGCGTGGGGCGGTTTCTCGAACACTTCCGCCCGCGCCTTG
CGTTGATCCTGGAAACCGAGCTGTGGCCGAACATGTTGTTCGGCTGCCGCGATCGCCAGATTCCGGTGTACATCCTCAAT
GCGCGGTTGTCGGCGCGTTCGTTGCGCGGCTATCGGTTGCTGGCACCGTTGATCAGTCGTGCGCTGCGCACCGTCACCTG
CGTGGCGGCGCAGTCGCAGGACGATGCCGAGCGGTTCGTCACCCTGGGCGCGCGCCCGGATCAGGTGATCGCGTTGGGCA
ATCTCAAGTTCGATATCGCCGCGCCGGCGCAATTGCAGGCGTTGGTCGCGCAGTTCCGCATGCACGTGCCGGCCACGCGC
CCGGTGTGGATCGCCGCCAGCACGCACGAAGGCGAAGAGGCGGCCGTCGCCGATATCCACGCACGTGTGCTGCTGCAATT
TCCGGACTTGCTGCTGTTGTGGGCGCCGCGCCATCCCGAGCGCTTTCCCAAGGTCGAGACATTGGCACGCGAGCGCGGTT
GGCGCGTTGCCACGCGCAAGACCCAGCAATGGCCGCAGGCAGGCGACAAGGTATTCGTCATCGACACCCTGGGCGAGCTG
ATGAGCTTCTATGCGTGCGCGCAGGTGGCTTTCGTCGGTGGCAGCTTGCAGCCAATTGGCGGACACAACCTGCTCGAGCC
GGCCGCCGTCGGCACGCCGGCAATCACTGGCCCGCATCTGCATAACTTCTCGGAGATTTCGCGGCGCATGCGCCAAGCCG
ATGCCGTTGCCATCTGCGAGGATGCCGAGTGCGTCTACCAGGCGTTGGCGCGCCTGCTCGCCGACCCCGCACAACGCGAG
GCGATGGCCGCTGCGGGCCTGGCGCTGGTCGCCAATGGCAAGGGCGCCGTGACCCGCACATTGGTGCGGATCGCTCCCGA
TCTGCCGCCGCTGGCGAACGAGGGCGTTGCGGCGTGA

Upstream 100 bases:

>100_bases
GCTTCGCACTCACCTCAACGTACATAACACGCTCTAAGGGATTGCAGCCAGCGGGCAGCGTGCACATGCGCACGCACGGA
CGCTCCCGTATCCTGCACCG

Downstream 100 bases:

>100_bases
GGTTTGTCGCTCGGTGCGTGGCTGCGTGCATGGACGTGCCGCACTCCACCGAGGCCCGCCGCCGGATTGCCGCCTTCGTT
GCGTTCAGTGGCGAGAGCGT

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNAAAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPDQVIALGNLKFDIAAPAQLQALVAQFRMHVPATR
PVWIAASTHEGEEAAVADIHARVLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKTQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMAAAGLALVANGKGAVTRTLVRIAPDLPPLANEGVAA

Sequences:

>Translated_438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNAAAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPDQVIALGNLKFDIAAPAQLQALVAQFRMHVPATR
PVWIAASTHEGEEAAVADIHARVLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKTQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMAAAGLALVANGKGAVTRTLVRIAPDLPPLANEGVAA
>Mature_438_residues
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVWVHAVSVGEVNAAAPLVNALR
AQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPGSVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILN
ARLSARSLRGYRLLAPLISRALRTVTCVAAQSQDDAERFVTLGARPDQVIALGNLKFDIAAPAQLQALVAQFRMHVPATR
PVWIAASTHEGEEAAVADIHARVLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRKTQQWPQAGDKVFVIDTLGEL
MSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHLHNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQRE
AMAAAGLALVANGKGAVTRTLVRIAPDLPPLANEGVAA

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=422, Percent_Identity=46.4454976303318, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 48703; Mature: 48703

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VHAVSVGEVNAAAPLVNALRAQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPG
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEECCCCCC
SVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILNARLSARSLRGYRLLAPLISR
HHHHHHHHHCCCEEEEEECHHCHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
ALRTVTCVAAQSQDDAERFVTLGARPDQVIALGNLKFDIAAPAQLQALVAQFRMHVPATR
HHHHHHHHHCCCCCCHHHHEECCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHCCCCCC
PVWIAASTHEGEEAAVADIHARVLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEHHH
TQQWPQAGDKVFVIDTLGELMSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHL
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQREAMAAAGLALVANGKGAVTRT
CCHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHH
LVRIAPDLPPLANEGVAA
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKDPIEWLLRGLYSALLYLLLPVTVYHLVWRGFRVREYFNRWNERYASYTHACGRPRVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VHAVSVGEVNAAAPLVNALRAQRPDIRWVITTITPTGSERVRALWGDAVDHVYLPYDVPG
EEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEECCCCCC
SVGRFLEHFRPRLALILETELWPNMLFGCRDRQIPVYILNARLSARSLRGYRLLAPLISR
HHHHHHHHHCCCEEEEEECHHCHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
ALRTVTCVAAQSQDDAERFVTLGARPDQVIALGNLKFDIAAPAQLQALVAQFRMHVPATR
HHHHHHHHHCCCCCCHHHHEECCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHCCCCCC
PVWIAASTHEGEEAAVADIHARVLLQFPDLLLLWAPRHPERFPKVETLARERGWRVATRK
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEHHH
TQQWPQAGDKVFVIDTLGELMSFYACAQVAFVGGSLQPIGGHNLLEPAAVGTPAITGPHL
HHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HNFSEISRRMRQADAVAICEDAECVYQALARLLADPAQREAMAAAGLALVANGKGAVTRT
CCHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHH
LVRIAPDLPPLANEGVAA
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]