Click here to switch to the map view.

The map label for this gene is acrE [C]

Identifier: 21244052

GI number: 21244052

Start: 3918510

End: 3919580

Strand: Reverse

Name: acrE [C]

Synonym: XAC3327

Alternate gene names: 21244052

Gene position: 3919580-3918510 (Counterclockwise)

Preceding gene: 21244053

Following gene: 21244051

Centisome position: 75.73

GC content: 66.01

Gene sequence:

>1071_bases
ATGCTTGTTCTGCCCAGCGCGCGCGTTTGCGCCGCGCTCTTGTTGGCCGTTGTGCTGGTCGGTTGTAGCCGTCAGGCCAG
CACGCCGGCCGCTGCCAAACCCATTCCGGTCTCTGTGCAGGCGGTGGCCACCCAACCCTGGAACTCGACCGTGCAGTCGA
TCGCTACCGTGCGCGCGCGCGAATCGGTGGCGCTCACCGCTGCAGTCAGCGATGTGGTGGAACAGGTGTATTTCGACAGC
GGCGACGAGGTCAAGGCCGGGCAATTGCTGCTGCGTCTGCGCGGCAATTCGCAGCAGGCGGCGTTGACTGCCGCACAGGC
CACCTTCGAAGAAACCGACCAGCTGTACCGCCGCCAGTTGAGTCTGGTTGGCCAGCAATTGGTGGCCAAATCCACCGTGG
ACACGCAACGCGCCTTACGCGATGCCGCGCATGCGCGCGTGCAGCAGATGCGCGCGGAAATCACCGACCGCGAAGTGCGT
GCGCCGTTTTCCGGCGTGCTGGGCATCCGCCAGATCAGTCCTGGTTCGCTGATCACCTCCAGCACGGTGATCGCCACGCT
GGACGATGTGGCGCGTATGTACGTGGATTTCCAGGTGCCGGAATCGCAGTTCGGCCTGGTGCAACTCGGTAATGCCGTGA
GCGGTAGCGCGGCGGCGTATCCGGGCGCGCAGTTCCAGGGCGAAGTGGTGACCATCGATTCGCGGATCGACGAAACCACG
CGCTCGGTGACGGTGCGTGCTGACTTTCCCAACGACGATCGCCGGCTGCGCCCGGGCATGTTGCTGGATGTGCGGTTGTT
CCAGCCGGCGCGGCAGGCGGTGGTGATCCCGGAAATTGCGGTGGTGCAGGTGGGGCGCGAATCGTATGTGTTCCGGGTCA
AGCCCGACAGCACCGTGGAGCGCGCCGATGTACGGCTGGGCGAGCGCCGCGATGGCAAGGTGGAAATTCTCGAAGGCGTC
AGGGCCGGTGAGCGCATCGTGGTGGATGGCACCGGCAAGCTGCGCCCGGGCGTGAAGGTTGCCGATCAGGCGCCACCCGC
AGCACCCCGCCCGCAGGCGGCCGCACAATGA

Upstream 100 bases:

>100_bases
GACGGCAAGGGTCTTTGGTCATGGTGCAAAGCGCGCCCTTTCTGTCAATTCATGGCGGCTAGGTCGGTAAACTTTCGACG
TACCCCGCCAGGATGTCCTG

Downstream 100 bases:

>100_bases
AACTCTCCGACCTGTCGATCACCCGCCCGGTGATGGCGGTGGTGATGAGTTTGCTGCTGATCGTGTTGGGGGTGATGTCG
TTCACCCGCCTTACGCTGCG

Product: RND efflux membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLVLPSARVCAALLLAVVLVGCSRQASTPAAAKPIPVSVQAVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDS
GDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDREVR
APFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGV
RAGERIVVDGTGKLRPGVKVADQAPPAAPRPQAAAQ

Sequences:

>Translated_356_residues
MLVLPSARVCAALLLAVVLVGCSRQASTPAAAKPIPVSVQAVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDS
GDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDREVR
APFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGV
RAGERIVVDGTGKLRPGVKVADQAPPAAPRPQAAAQ
>Mature_356_residues
MLVLPSARVCAALLLAVVLVGCSRQASTPAAAKPIPVSVQAVATQPWNSTVQSIATVRARESVALTAAVSDVVEQVYFDS
GDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDREVR
APFSGVLGIRQISPGSLITSSTVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVERADVRLGERRDGKVEILEGV
RAGERIVVDGTGKLRPGVKVADQAPPAAPRPQAAAQ

Specific function: May Affect Specific Membrane Functions, Such As Septum Formation During Cell Division, And Cell Membrane Permeability. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=377, Percent_Identity=27.5862068965517, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786668, Length=372, Percent_Identity=27.1505376344086, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082036, Length=311, Percent_Identity=27.6527331189711, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789929, Length=365, Percent_Identity=24.9315068493151, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38212; Mature: 38212

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLPSARVCAALLLAVVLVGCSRQASTPAAAKPIPVSVQAVATQPWNSTVQSIATVRAR
CEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
ESVALTAAVSDVVEQVYFDSGDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDREVRAPFSGVLGIRQISPGSLITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCCCCEEEC
STVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
CHHHHHHHHHHHHHEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVE
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCEEEEECCCCCHH
RADVRLGERRDGKVEILEGVRAGERIVVDGTGKLRPGVKVADQAPPAAPRPQAAAQ
HHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVLPSARVCAALLLAVVLVGCSRQASTPAAAKPIPVSVQAVATQPWNSTVQSIATVRAR
CEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
ESVALTAAVSDVVEQVYFDSGDEVKAGQLLLRLRGNSQQAALTAAQATFEETDQLYRRQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDREVRAPFSGVLGIRQISPGSLITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCCCCEEEC
STVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGSAAAYPGAQFQGEVVTIDSRIDETT
CHHHHHHHHHHHHHEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
RSVTVRADFPNDDRRLRPGMLLDVRLFQPARQAVVIPEIAVVQVGRESYVFRVKPDSTVE
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCEEEEECCCCCHH
RADVRLGERRDGKVEILEGVRAGERIVVDGTGKLRPGVKVADQAPPAAPRPQAAAQ
HHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]