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The map label for this gene is recQ [H]

Identifier: 21243851

GI number: 21243851

Start: 3677076

End: 3678872

Strand: Direct

Name: recQ [H]

Synonym: XAC3124

Alternate gene names: 21243851

Gene position: 3677076-3678872 (Clockwise)

Preceding gene: 21243850

Following gene: 21243852

Centisome position: 71.05

GC content: 66.05

Gene sequence:

>1797_bases
ATGTCTTCCCCCGCCCACGAACTGCTCAGCCGCGTCTTTGGCTACGACGACTTCCGCGGCCCGCAGCAGGCCATTGTCGA
ACACGTCGCTGCCGGCAACGATGCCCTGGTCCTCATGCCCACCGGTGGCGGCAAATCGCTGTGCTACCAGGTGCCGGCGC
TGCTACGCGACGGCATCGGCATCGTGGTCTCGCCGCTGATCGCGCTGATGCAGGATCAGGTCGAGGCCCTGCGCCAGCTC
GGCGTGCGCGCCGAGTTCCTCAATTCCACCCTGGATGCAGAAAACGCCCAGCGCGTGGAACGCGCCCTGCTGTCCGGCGA
CCTGGATCTGCTCTACGTTGCGCCGGAGCGCCTGCTGACCCAGCGCTTCCTTTCATTGCTGGAACGTAGCCGCATTGCGC
TATTCGCCATCGACGAAGCGCATTGCGTCTCGCAATGGGGCCACGATTTCCGCCCGGAATACCGCCAGCTCACCGTACTG
CATGAGCGCTGGCCGCATGTACCGCGCATGGCGTTGACGGCCACCGCCGACCCGCCGACCCAGCGCGAGATCGCAGAGCG
CCTGGATCTGGTAGACGCGCGCCACTTCGTCAGTTCCTTCGACCGCCCCAACATCCGCTACACGGTGGTGCAGAAGGACA
ATGCGCGCAAACAGCTGCAGGAATTCCTGGGCCGTCATCGTGGCTCGGCCGGCATCGTCTATGCGATGTCGCGGCGCAAG
GTGGAAGAAACCGCGCAGCAACTGTGCGCGCAAGGCTTCAATGCACTGCCCTATCACGCCGGCCTGCCGGCAGAGGTACG
CGCAGAAAACCAGCGCCGCTTCCTGCGCGAGGACGGCATCATCATGGCCGCCACGATCGCTTTCGGCATGGGCATCGACA
AGCCGGACGTGCGCTTCGTGGCGCACGTGGATCTGCCCAAATCGCTTGAGGGCTACTACCAGGAAACCGGACGCGCCGGC
CGCGACGGCGATCCCGCCGAGGCCTGGCTGTGCTACGGCCTGGGCGATGTGGTGCTGCTCAAGCAGATGATCGAGCAGGG
CGAAGCGGCCGAAGAGCGCAAGCGTCTGGAGCGCGCCAAGCTCGACCACCTGCTGGGCTATTGCGAATCGATGCAATGCC
GTCGCCAGGTGCTGCTGGCCGGCTTCGGCGAGACCTATCCCAAACCCTGCGGCAACTGCGACAACTGCCTGACCCCGGCC
GCCGCCTGGGACGCCACGGTGGCCTCGCAGAAGGCGCTCAGTTGCGTCTACCGCAGCGGGCAGCGCTTTGGCGTGGGTCA
TCTGATCGACATCCTGCGCGGTAGCGAAAACGAGCGTATCAAACAGCTGGGGCACGACCAGCTCAGCACCTACGGTATCG
GCCGCGATCTGGACGAACGCACCTGGCGCGGCGTGTTTCGCCAACTGGTGGCCGCCAGCCTGCTGGAAGTCGATAGCGAA
GGTCACGGCGGCCTACGCCTCACCGATGCCAGCCGCCAGGTGCTCAAGGGCGAGCGCCAGGTCATGATGCGCCGCGAAAA
CCCGGCTGCCGGGCGCGAGCGTAGCGCGCAGCGCACCGGCCTGCCGGTGCAGCCGCAGGATCTGGCGCTGTTCAATGCCT
TGCGCGGCTTGCGCGCGGATCTGGCCAAGGAACAGAACGTGCCGGCCTTCGTGATCTTCCATGACAGCACCTTGCGCAAC
ATCGCCGAACAACGGCCAACCAGCATCGATGCGCTCTCGCGGGTGGGCGGCATCGGCGGCGGCAAGCTGGCGCGCTACGG
CGCGCAATTGATCGAGATCGTGCGCGAACAGGGCTGA

Upstream 100 bases:

>100_bases
CAACCCAACATCCACATCACGGCAATCCCTGATGCGGCTTCGCGCAACTCCACCCAGCAACACCCCGGCCAGGGCTTGAC
CCGCACGGTATCCTAGGCGG

Downstream 100 bases:

>100_bases
TGCAGCAGCGTGTGTCAACACAACACCGCAGACGGCACAAAAATCCGCAAGATCGACAGCGCGCATTCAATCAGCCGTTG
CTAGTTTCACACAGCGAGCT

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQL
GVRAEFLNSTLDAENAQRVERALLSGDLDLLYVAPERLLTQRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVL
HERWPHVPRMALTATADPPTQREIAERLDLVDARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSLEGYYQETGRAG
RDGDPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPA
AAWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDLDERTWRGVFRQLVAASLLEVDSE
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERSAQRTGLPVQPQDLALFNALRGLRADLAKEQNVPAFVIFHDSTLRN
IAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG

Sequences:

>Translated_598_residues
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQL
GVRAEFLNSTLDAENAQRVERALLSGDLDLLYVAPERLLTQRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVL
HERWPHVPRMALTATADPPTQREIAERLDLVDARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSLEGYYQETGRAG
RDGDPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPA
AAWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDLDERTWRGVFRQLVAASLLEVDSE
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERSAQRTGLPVQPQDLALFNALRGLRADLAKEQNVPAFVIFHDSTLRN
IAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
>Mature_597_residues
SSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQLG
VRAEFLNSTLDAENAQRVERALLSGDLDLLYVAPERLLTQRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLH
ERWPHVPRMALTATADPPTQREIAERLDLVDARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRKV
EETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSLEGYYQETGRAGR
DGDPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAA
AWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDLDERTWRGVFRQLVAASLLEVDSEG
HGGLRLTDASRQVLKGERQVMMRRENPAAGRERSAQRTGLPVQPQDLALFNALRGLRADLAKEQNVPAFVIFHDSTLRNI
AEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=634, Percent_Identity=35.0157728706625, Blast_Score=354, Evalue=1e-97,
Organism=Homo sapiens, GI14591902, Length=415, Percent_Identity=38.0722891566265, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI14591904, Length=415, Percent_Identity=38.0722891566265, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI148612816, Length=428, Percent_Identity=41.588785046729, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI51242943, Length=398, Percent_Identity=42.2110552763819, Blast_Score=273, Evalue=4e-73,
Organism=Homo sapiens, GI51242947, Length=395, Percent_Identity=42.2784810126582, Blast_Score=273, Evalue=5e-73,
Organism=Homo sapiens, GI169218196, Length=498, Percent_Identity=34.9397590361446, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI110735439, Length=498, Percent_Identity=34.9397590361446, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI284005309, Length=342, Percent_Identity=35.3801169590643, Blast_Score=169, Evalue=7e-42,
Organism=Escherichia coli, GI48994977, Length=595, Percent_Identity=46.3865546218487, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI87082221, Length=345, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=500, Percent_Identity=38.2, Blast_Score=342, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI71987997, Length=410, Percent_Identity=40.9756097560976, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71987993, Length=410, Percent_Identity=40.9756097560976, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=678, Percent_Identity=31.2684365781711, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17552866, Length=412, Percent_Identity=37.8640776699029, Blast_Score=254, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6323844, Length=552, Percent_Identity=34.2391304347826, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6324217, Length=339, Percent_Identity=23.8938053097345, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646066, Length=625, Percent_Identity=36.16, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=452, Percent_Identity=38.716814159292, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24664230, Length=452, Percent_Identity=38.716814159292, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI62472181, Length=452, Percent_Identity=38.716814159292, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.3636363636364, Blast_Score=201, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66544; Mature: 66413

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIG
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
IVVSPLIALMQDQVEALRQLGVRAEFLNSTLDAENAQRVERALLSGDLDLLYVAPERLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECHHHHHH
QRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLHERWPHVPRMALTATADPPT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
QREIAERLDLVDARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHH
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCEEE
AHVDLPKSLEGYYQETGRAGRDGDPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAK
EECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAAAWDATVASQKALSCVYRSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDLDERTWRGVFRQLVAASLLEVDSE
CCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERSAQRTGLPVQPQDLALFNALRGLRAD
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LAKEQNVPAFVIFHDSTLRNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
HHHCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIG
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
IVVSPLIALMQDQVEALRQLGVRAEFLNSTLDAENAQRVERALLSGDLDLLYVAPERLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECHHHHHH
QRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLHERWPHVPRMALTATADPPT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
QREIAERLDLVDARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHH
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCEEE
AHVDLPKSLEGYYQETGRAGRDGDPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAK
EECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAAAWDATVASQKALSCVYRSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDLDERTWRGVFRQLVAASLLEVDSE
CCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERSAQRTGLPVQPQDLALFNALRGLRAD
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LAKEQNVPAFVIFHDSTLRNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
HHHCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]