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The map label for this gene is yyaJ [H]

Identifier: 21242454

GI number: 21242454

Start: 1964553

End: 1965977

Strand: Reverse

Name: yyaJ [H]

Synonym: XAC1705

Alternate gene names: 21242454

Gene position: 1965977-1964553 (Counterclockwise)

Preceding gene: 21242457

Following gene: 21242451

Centisome position: 37.99

GC content: 64.42

Gene sequence:

>1425_bases
ATGTCTGCGAGTGCTTCAGCGCGCCCCGAACAGCCCTCGTCTTCTGCGCAGATCGCCGCCCGGATCGATCGGTTGCCAGC
CAGCGCCACACTGTGGCGGTTGGTGGGGTTGCTGGCGCTGGGCGGGTTCTTCGAGTTGTACGACCTGTTCCAGACCGCAT
ACATCAGCCCCGGGCTGATTGGCGACGGCATTTTTGCCAACGGCGCCGACGGCGCGTTCGGCATGTCCGATCAAGCCGCA
TTTGCGGCGGCCACCTTCCTTGGGTTGTTTGTCGGCGCCGCGCTATTGAGCCCGTTTGCCGACCGGTTCGGGCGTCGCCC
GGTGTTTACCTTCGCCTTGATCTGGTACACCGCTGCGACCGTGGCGATGGGTCTGCAGAGCACTGCCAGCGGTGTCATCG
TGCTGCGCTTTGTGGTCGGCATCGGGTTGGGAATCGAACTGGTCACCATCGATACGTATCTATCCGAACTGGTACCGCGG
CACATGCGCAGTGCGGCGTTTGCATTTGCATTTTTCGTGCAATTTCTGGCGGTACCGACGGTCGCGCTGACCGCATGGAT
GTTGGTGCCGTCTGCGCCGCTGGGGGTGAGCGGCTGGCGCTGGGTGGTGTTGCTCAGCGGCGCGTTTGCGCTGGCGATCT
GGTGGCTGCGCAGCCGCTTGCCGGAATCGGCGCGCTGGCTGGCCGCGCACGGCCGGCACGCAGAAGCCGATGCCGTGCTG
ACCGAACTGGAGGCGCGCTGCACGCGCGATGTGGGTGCGCCATTGCCCGCGCCGCAGGCGGCCACAGCCACGCAGGCCAG
CGTGATGCTGAGCGCGCCGCTGTGGCGTGCGCCGTATCGCGGGCGCATCGGCATGTTGGTGGTCTTCCATGTGTTTCAGG
CGATCGGCTTCTTCGGCTTCGGTAACTGGTTGCCTGCGCTGATCTCGGCGCAGGGCACCGGAGCCGGGGTGACCAAGAGC
CTGGCGTATTCGTTTGCGATCTCGTTGGCCTACCCGCTGGCGCCATTGCTGTTGCTGCGTTTTGCGCAGCGCTGGGAAAA
CAAATGGCAGATCACCGCGTCGGCGCTGGGCGCTGTTCTGTTCGGTGGGCTGTTCGCGGTGCAGCATCACGCCGTCGGCA
TGGTGCTGTGCGGGGCGATGGTCGCGTTCTGCAACGCGTGGATGAGCTTTGCCTATCACGGCTATCAAGCGGAGCTGTTC
CCGACCGGCTTACGTGCACGTGCAGTGGGCTTTTGCTATTCCTTCAGTCGCCTCTCCACGGCAGTGAGCAGCGTGCTGAT
CGGCTGGTTGCTGACGCAGGTTGGCAGCCATGGCGTGCTGGCCTTCATCGCGCTCAGCATGTCGATCGTGGCGAGCGTGA
TTGCGGTGTTCGGCCCACGCACGCGCAATCGTGCACTGGAAGACATTGCAGGTGAGTACGGATGA

Upstream 100 bases:

>100_bases
CTCATCACAGACGAACGCATCGACCGCGCGACGAAGCGTGCCCGCTGCGGCATCTGGACGCTGGCTATGATGACGCGGTC
CCGTCTGCCCCTGTCTTCCC

Downstream 100 bases:

>100_bases
TGAAACGCCTGCGGAAGGCCAGACGTGTAAGCCATCGTGCTGCGTGTGGTTTAGCGCACGTCGGTGCGTGCCCGACAACG
GTCTCGGTTCTGTCAGCGAT

Product: MFS transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSASASARPEQPSSSAQIAARIDRLPASATLWRLVGLLALGGFFELYDLFQTAYISPGLIGDGIFANGADGAFGMSDQAA
FAAATFLGLFVGAALLSPFADRFGRRPVFTFALIWYTAATVAMGLQSTASGVIVLRFVVGIGLGIELVTIDTYLSELVPR
HMRSAAFAFAFFVQFLAVPTVALTAWMLVPSAPLGVSGWRWVVLLSGAFALAIWWLRSRLPESARWLAAHGRHAEADAVL
TELEARCTRDVGAPLPAPQAATATQASVMLSAPLWRAPYRGRIGMLVVFHVFQAIGFFGFGNWLPALISAQGTGAGVTKS
LAYSFAISLAYPLAPLLLLRFAQRWENKWQITASALGAVLFGGLFAVQHHAVGMVLCGAMVAFCNAWMSFAYHGYQAELF
PTGLRARAVGFCYSFSRLSTAVSSVLIGWLLTQVGSHGVLAFIALSMSIVASVIAVFGPRTRNRALEDIAGEYG

Sequences:

>Translated_474_residues
MSASASARPEQPSSSAQIAARIDRLPASATLWRLVGLLALGGFFELYDLFQTAYISPGLIGDGIFANGADGAFGMSDQAA
FAAATFLGLFVGAALLSPFADRFGRRPVFTFALIWYTAATVAMGLQSTASGVIVLRFVVGIGLGIELVTIDTYLSELVPR
HMRSAAFAFAFFVQFLAVPTVALTAWMLVPSAPLGVSGWRWVVLLSGAFALAIWWLRSRLPESARWLAAHGRHAEADAVL
TELEARCTRDVGAPLPAPQAATATQASVMLSAPLWRAPYRGRIGMLVVFHVFQAIGFFGFGNWLPALISAQGTGAGVTKS
LAYSFAISLAYPLAPLLLLRFAQRWENKWQITASALGAVLFGGLFAVQHHAVGMVLCGAMVAFCNAWMSFAYHGYQAELF
PTGLRARAVGFCYSFSRLSTAVSSVLIGWLLTQVGSHGVLAFIALSMSIVASVIAVFGPRTRNRALEDIAGEYG
>Mature_473_residues
SASASARPEQPSSSAQIAARIDRLPASATLWRLVGLLALGGFFELYDLFQTAYISPGLIGDGIFANGADGAFGMSDQAAF
AAATFLGLFVGAALLSPFADRFGRRPVFTFALIWYTAATVAMGLQSTASGVIVLRFVVGIGLGIELVTIDTYLSELVPRH
MRSAAFAFAFFVQFLAVPTVALTAWMLVPSAPLGVSGWRWVVLLSGAFALAIWWLRSRLPESARWLAAHGRHAEADAVLT
ELEARCTRDVGAPLPAPQAATATQASVMLSAPLWRAPYRGRIGMLVVFHVFQAIGFFGFGNWLPALISAQGTGAGVTKSL
AYSFAISLAYPLAPLLLLRFAQRWENKWQITASALGAVLFGGLFAVQHHAVGMVLCGAMVAFCNAWMSFAYHGYQAELFP
TGLRARAVGFCYSFSRLSTAVSSVLIGWLLTQVGSHGVLAFIALSMSIVASVIAVFGPRTRNRALEDIAGEYG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=403, Percent_Identity=25.5583126550869, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI296080721, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296080734, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296080719, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI24497499, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788068, Length=470, Percent_Identity=26.1702127659574, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788074, Length=470, Percent_Identity=25.7446808510638, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082159, Length=356, Percent_Identity=29.2134831460674, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786229, Length=391, Percent_Identity=25.3196930946292, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082231, Length=179, Percent_Identity=29.0502793296089, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082404, Length=204, Percent_Identity=25.9803921568627, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19922616, Length=410, Percent_Identity=24.8780487804878, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50549; Mature: 50418

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASASARPEQPSSSAQIAARIDRLPASATLWRLVGLLALGGFFELYDLFQTAYISPGLI
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDGIFANGADGAFGMSDQAAFAAATFLGLFVGAALLSPFADRFGRRPVFTFALIWYTAAT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAMGLQSTASGVIVLRFVVGIGLGIELVTIDTYLSELVPRHMRSAAFAFAFFVQFLAVPT
HHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALTAWMLVPSAPLGVSGWRWVVLLSGAFALAIWWLRSRLPESARWLAAHGRHAEADAVL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHH
TELEARCTRDVGAPLPAPQAATATQASVMLSAPLWRAPYRGRIGMLVVFHVFQAIGFFGF
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHH
GNWLPALISAQGTGAGVTKSLAYSFAISLAYPLAPLLLLRFAQRWENKWQITASALGAVL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FGGLFAVQHHAVGMVLCGAMVAFCNAWMSFAYHGYQAELFPTGLRARAVGFCYSFSRLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
AVSSVLIGWLLTQVGSHGVLAFIALSMSIVASVIAVFGPRTRNRALEDIAGEYG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SASASARPEQPSSSAQIAARIDRLPASATLWRLVGLLALGGFFELYDLFQTAYISPGLI
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDGIFANGADGAFGMSDQAAFAAATFLGLFVGAALLSPFADRFGRRPVFTFALIWYTAAT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAMGLQSTASGVIVLRFVVGIGLGIELVTIDTYLSELVPRHMRSAAFAFAFFVQFLAVPT
HHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALTAWMLVPSAPLGVSGWRWVVLLSGAFALAIWWLRSRLPESARWLAAHGRHAEADAVL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHH
TELEARCTRDVGAPLPAPQAATATQASVMLSAPLWRAPYRGRIGMLVVFHVFQAIGFFGF
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHH
GNWLPALISAQGTGAGVTKSLAYSFAISLAYPLAPLLLLRFAQRWENKWQITASALGAVL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FGGLFAVQHHAVGMVLCGAMVAFCNAWMSFAYHGYQAELFPTGLRARAVGFCYSFSRLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
AVSSVLIGWLLTQVGSHGVLAFIALSMSIVASVIAVFGPRTRNRALEDIAGEYG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]