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The map label for this gene is cycJ

Identifier: 21242426

GI number: 21242426

Start: 1936321

End: 1936791

Strand: Reverse

Name: cycJ

Synonym: XAC1677

Alternate gene names: 21242426

Gene position: 1936791-1936321 (Counterclockwise)

Preceding gene: 21242427

Following gene: 21242425

Centisome position: 37.42

GC content: 63.91

Gene sequence:

>471_bases
ATGAACGCCACGCGCAAACAACGTCTGTGGCTGGTGATCGGCGTACTGGCCGCCGCCGCGCTGGCCGTCACGCTCATCGT
GTTCGCCTTGCAGCGGAACATGAGCTACCTGTTCACCCCAAGCCAGGTCCGCGCGGGGGAAGCCGCCGGCTACCAGCAAT
TCCGGCTCGGCGGCATGGTCAAGGCCGGCTCGATCCAGCGTGCCGGTGATTCGCTGAAGGTCAGCTTCATCGTCATCGAT
AAAAACGCAGCGACCCAGGTGGAGTACACCGGCATTCTTCCGGACCTGTTTCGCGATAACCAGTCGGTCATCGCCAACGG
GCGCATGCAGGGCGGGCGCTTTGTCGCCAACGAAGTGCTGGCCAAGCACGACGAGACCTACATGCCGAAAGAGCTGAAGG
ATGCGATGGCGCAGGGCCACCTTGGCAAGCCAGTTCCCGCCACCGTCGCACCGCTGACCGCGCCGCGTTGA

Upstream 100 bases:

>100_bases
GCCGCCGCCGGCTGCCGCGCGAACTGCGCGGCCAGTTGCAGCGGCAGGCACCGTGGCGTGTACGCGATCAACCGGCACCG
GCACTGGACCGCGAAGCGCC

Downstream 100 bases:

>100_bases
TGCGCTTGCGGTCATTGCCACGCACGTCGATGACGTCCTCTTTCCGTTTCACCTTGCGATCCGCCCATGACGCCTGAACT
CGGCCAGATCGCACTGATCC

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNATRKQRLWLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFIVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAQGHLGKPVPATVAPLTAPR

Sequences:

>Translated_156_residues
MNATRKQRLWLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFIVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAQGHLGKPVPATVAPLTAPR
>Mature_156_residues
MNATRKQRLWLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFIVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAQGHLGKPVPATVAPLTAPR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=147, Percent_Identity=43.5374149659864, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME1_XANAC (Q8PLW2)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642008.1
- ProteinModelPortal:   Q8PLW2
- SMR:   Q8PLW2
- GeneID:   1155748
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1677
- NMPDR:   fig|190486.1.peg.1652
- HOGENOM:   HBG296631
- OMA:   ENISFFY
- ProtClustDB:   PRK13159
- BioCyc:   XAXO190486:XAC1677-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 16885; Mature: 16885

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: BINDING 123-123

Signals:

None

Transmembrane regions:

HASH(0xf037490)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATRKQRLWLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGEAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCCCCCCHHHHHHCCEE
KAGSIQRAGDSLKVSFIVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
ECCCCCCCCCCEEEEEEEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAQGHLGKPVPATVAPLTAPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNATRKQRLWLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGEAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCCCCCCHHHHHHCCEE
KAGSIQRAGDSLKVSFIVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
ECCCCCCCCCCEEEEEEEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAQGHLGKPVPATVAPLTAPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217