Click here to switch to the map view.

The map label for this gene is intA [H]

Identifier: 21242413

GI number: 21242413

Start: 1918024

End: 1919214

Strand: Reverse

Name: intA [H]

Synonym: XAC1664

Alternate gene names: 21242413

Gene position: 1919214-1918024 (Counterclockwise)

Preceding gene: 21242415

Following gene: 21242411

Centisome position: 37.08

GC content: 57.77

Gene sequence:

>1191_bases
ATGCCCAGGACTCACCATAGGCTCTCGCCTACGTTCGTCAATGCGGCGAAGAAAGGAAACGCAAAGCCTGGCCGATACTC
CGATGGGGGAAATCTAGCGCTACGCGTCGGCGAAGGCGGAGCGGCTAGCTGGACTTTCGAATTTGTCCGAGCAGGCCAGC
GCAGAGAGCTAGGCTTAGGGTCAGTAGGCGTTGTTGGTTTGGCAGATGCAAGGGCGCGAGCCGCCTCGTTGCGCTCAGAC
CTGGCCGCAGGCATAACGCCGCAAACTGCTCGCGCACGCACCCAGGCAAACATCGGGCTTACGTTTCGACAAGCGACGGA
AAAGTACCTTTCCGGCAAAGTGTCGGCCATGAAGAACGACAAGCACAAAGCGCAGTGGCGCAGCACCCTTGAAACGTATG
CCTACCCTTACATCGGCGACCTCGACGTAAAACAGATCGATACACCTCATGTGCTTGCGGCGCTTGATCCAATCTGGATT
ACGAAAAACGAGACCGCCAGCCGCGTGCGCGGGCGCATCGAACGAGTCCTAGCGTGGGCGACAGTGAGCGGACATCGTAC
TGGGGACAATCCGGCGCGCTGGCGCGGTCATCTTTCGGAGGCACTTGCAGCACCAGCACAGGCCAAGAAAGTTGAACACC
ACGCGGCCCTGCCCTACGCAGAACTTCCTGCATTCCTATCGGCGCTGCAAGGCCAAATCGGCATTGGAGCGCACGCGCTG
CGTTTCGCGATCCTGACAGCCACGAGAACTGGCGAAGTCATTGGCGCCCGCTGGGATGAATTCGATTTGGAGGAAAACGT
GTGGACGATTCCTGTAGAGCGGATGAAAGCAGGCAAGGAACACCGAGTGCCGCTAAGCAGCGCCGCCCTTGAAATTCTTT
CTGCAATGAGGAATTTCGCCACCGGAAGTGGCGACGGCTTTGTTTTTCCAGGGGCGAAGAATGGAAGCCCATTATCGAAC
ATGGCAATGCTTGCAACCCTTAAAAGGATGGGTCGGACTGACATCACCGCGCACGGGTTCCGCTCAACTTTTCGCGATTG
GGCTGGGCAGGAAACACACCATCCACGCGAGGTTATTGAACATGCTCTGGCGCACCAGCTTAAAAGTAAAACTGAAGCTG
CCTACGCGCGGGGCGACTTGCTCAGGAAGCGCCGCGCGTTGATGGATGAGTGGGCAACCTACGCAGCTTAA

Upstream 100 bases:

>100_bases
CCATTCAAATTCAACAATTTGCGTCGACTTTGCGTCTCACAAGGCATCGCAAAATTTGATATGATCGCAGGGACAAACAC
GGAAAAAACCCGGAGTACCA

Downstream 100 bases:

>100_bases
TTTGCATGTCGCAGGGTATTCACATGCAAAATCGCCATGTGAATAGAGCATCCCAAGTCGTTGATCTGTAAACCCATTCC
CAAAAGTGAATAGTGTTCAA

Product: phage-related integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPRTHHRLSPTFVNAAKKGNAKPGRYSDGGNLALRVGEGGAASWTFEFVRAGQRRELGLGSVGVVGLADARARAASLRSD
LAAGITPQTARARTQANIGLTFRQATEKYLSGKVSAMKNDKHKAQWRSTLETYAYPYIGDLDVKQIDTPHVLAALDPIWI
TKNETASRVRGRIERVLAWATVSGHRTGDNPARWRGHLSEALAAPAQAKKVEHHAALPYAELPAFLSALQGQIGIGAHAL
RFAILTATRTGEVIGARWDEFDLEENVWTIPVERMKAGKEHRVPLSSAALEILSAMRNFATGSGDGFVFPGAKNGSPLSN
MAMLATLKRMGRTDITAHGFRSTFRDWAGQETHHPREVIEHALAHQLKSKTEAAYARGDLLRKRRALMDEWATYAA

Sequences:

>Translated_396_residues
MPRTHHRLSPTFVNAAKKGNAKPGRYSDGGNLALRVGEGGAASWTFEFVRAGQRRELGLGSVGVVGLADARARAASLRSD
LAAGITPQTARARTQANIGLTFRQATEKYLSGKVSAMKNDKHKAQWRSTLETYAYPYIGDLDVKQIDTPHVLAALDPIWI
TKNETASRVRGRIERVLAWATVSGHRTGDNPARWRGHLSEALAAPAQAKKVEHHAALPYAELPAFLSALQGQIGIGAHAL
RFAILTATRTGEVIGARWDEFDLEENVWTIPVERMKAGKEHRVPLSSAALEILSAMRNFATGSGDGFVFPGAKNGSPLSN
MAMLATLKRMGRTDITAHGFRSTFRDWAGQETHHPREVIEHALAHQLKSKTEAAYARGDLLRKRRALMDEWATYAA
>Mature_395_residues
PRTHHRLSPTFVNAAKKGNAKPGRYSDGGNLALRVGEGGAASWTFEFVRAGQRRELGLGSVGVVGLADARARAASLRSDL
AAGITPQTARARTQANIGLTFRQATEKYLSGKVSAMKNDKHKAQWRSTLETYAYPYIGDLDVKQIDTPHVLAALDPIWIT
KNETASRVRGRIERVLAWATVSGHRTGDNPARWRGHLSEALAAPAQAKKVEHHAALPYAELPAFLSALQGQIGIGAHALR
FAILTATRTGEVIGARWDEFDLEENVWTIPVERMKAGKEHRVPLSSAALEILSAMRNFATGSGDGFVFPGAKNGSPLSNM
AMLATLKRMGRTDITAHGFRSTFRDWAGQETHHPREVIEHALAHQLKSKTEAAYARGDLLRKRRALMDEWATYAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=389, Percent_Identity=32.6478149100257, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788974, Length=404, Percent_Identity=31.9306930693069, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1788690, Length=387, Percent_Identity=27.906976744186, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43264; Mature: 43132

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTHHRLSPTFVNAAKKGNAKPGRYSDGGNLALRVGEGGAASWTFEFVRAGQRRELGLG
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCC
SVGVVGLADARARAASLRSDLAAGITPQTARARTQANIGLTFRQATEKYLSGKVSAMKND
CCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHCC
KHKAQWRSTLETYAYPYIGDLDVKQIDTPHVLAALDPIWITKNETASRVRGRIERVLAWA
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
TVSGHRTGDNPARWRGHLSEALAAPAQAKKVEHHAALPYAELPAFLSALQGQIGIGAHAL
HCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHH
RFAILTATRTGEVIGARWDEFDLEENVWTIPVERMKAGKEHRVPLSSAALEILSAMRNFA
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
TGSGDGFVFPGAKNGSPLSNMAMLATLKRMGRTDITAHGFRSTFRDWAGQETHHPREVIE
CCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
HALAHQLKSKTEAAYARGDLLRKRRALMDEWATYAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRTHHRLSPTFVNAAKKGNAKPGRYSDGGNLALRVGEGGAASWTFEFVRAGQRRELGLG
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCC
SVGVVGLADARARAASLRSDLAAGITPQTARARTQANIGLTFRQATEKYLSGKVSAMKND
CCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHCC
KHKAQWRSTLETYAYPYIGDLDVKQIDTPHVLAALDPIWITKNETASRVRGRIERVLAWA
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
TVSGHRTGDNPARWRGHLSEALAAPAQAKKVEHHAALPYAELPAFLSALQGQIGIGAHAL
HCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHH
RFAILTATRTGEVIGARWDEFDLEENVWTIPVERMKAGKEHRVPLSSAALEILSAMRNFA
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
TGSGDGFVFPGAKNGSPLSNMAMLATLKRMGRTDITAHGFRSTFRDWAGQETHHPREVIE
CCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
HALAHQLKSKTEAAYARGDLLRKRRALMDEWATYAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]