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The map label for this gene is slyD [H]

Identifier: 21242111

GI number: 21242111

Start: 1566526

End: 1566999

Strand: Reverse

Name: slyD [H]

Synonym: XAC1358

Alternate gene names: 21242111

Gene position: 1566999-1566526 (Counterclockwise)

Preceding gene: 21242112

Following gene: 21242110

Centisome position: 30.28

GC content: 65.19

Gene sequence:

>474_bases
ATGGAAATCAGCCAGGGTCGCGTTGCGACCATTCACTACACCCTTTCCGACGACAACGGCCAAGTGCTGGACCGCTCCAC
GCCCGACACGCCGCTGAGTTATCTGCATGGCGCCGGCAACATCGTGCCCGGCCTGGAGCAGGCACTGGAAGGCAAGCAGC
TGGGCGATACGCTCACCGCCGACGTCGTGCCCGAACAGGGCTATGGTCCGCGTCATGAGCAGCTCATCCAGCAGGTGCCG
CGCGATGCGTTTCCGACCGATGTCGACGTCGTACCCGGCGTGCAGTTCGAAGCGCGCACGCAGCAGGGTCCGGTCCTGGT
CACCGTGACCGAGGTTGGCCCGGATCAGGTCACCGTGGACGGCAATCACCCGCTCGCTGGGCAAACACTGCACTTTGCGG
TCGAAGTGGTGGCAGTGCGCGAGGCCACCACGCAGGAATTGAACGACGGTCACGTGGCCGAGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCATGATGCGGTGCGATTGCCTACGGTGTGCGTGCGACACCTCTTCGCATCGTGAATCAGCCGATGCATTCCCTTCGATC
ATCCGTCATGGAGGTTTCCA

Downstream 100 bases:

>100_bases
CCCGGCGCGCGCCCCCGTGGCTGCGGCGGGGCCAGTGCGCAACACAACCCTTTCGCGTTTGGCCATGGCGTCACCGACGC
TGCCGGTCTCGACGGCAGGT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MEISQGRVATIHYTLSDDNGQVLDRSTPDTPLSYLHGAGNIVPGLEQALEGKQLGDTLTADVVPEQGYGPRHEQLIQQVP
RDAFPTDVDVVPGVQFEARTQQGPVLVTVTEVGPDQVTVDGNHPLAGQTLHFAVEVVAVREATTQELNDGHVAELAA

Sequences:

>Translated_157_residues
MEISQGRVATIHYTLSDDNGQVLDRSTPDTPLSYLHGAGNIVPGLEQALEGKQLGDTLTADVVPEQGYGPRHEQLIQQVP
RDAFPTDVDVVPGVQFEARTQQGPVLVTVTEVGPDQVTVDGNHPLAGQTLHFAVEVVAVREATTQELNDGHVAELAA
>Mature_157_residues
MEISQGRVATIHYTLSDDNGQVLDRSTPDTPLSYLHGAGNIVPGLEQALEGKQLGDTLTADVVPEQGYGPRHEQLIQQVP
RDAFPTDVDVVPGVQFEARTQQGPVLVTVTEVGPDQVTVDGNHPLAGQTLHFAVEVVAVREATTQELNDGHVAELAA

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=45.578231292517, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786211, Length=134, Percent_Identity=32.089552238806, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16751; Mature: 16751

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISQGRVATIHYTLSDDNGQVLDRSTPDTPLSYLHGAGNIVPGLEQALEGKQLGDTLTA
CCCCCCCEEEEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCEEEE
DVVPEQGYGPRHEQLIQQVPRDAFPTDVDVVPGVQFEARTQQGPVLVTVTEVGPDQVTVD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEC
GNHPLAGQTLHFAVEVVAVREATTQELNDGHVAELAA
CCCCCCCCHHEEEEEEEHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MEISQGRVATIHYTLSDDNGQVLDRSTPDTPLSYLHGAGNIVPGLEQALEGKQLGDTLTA
CCCCCCCEEEEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCEEEE
DVVPEQGYGPRHEQLIQQVPRDAFPTDVDVVPGVQFEARTQQGPVLVTVTEVGPDQVTVD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEC
GNHPLAGQTLHFAVEVVAVREATTQELNDGHVAELAA
CCCCCCCCHHEEEEEEEHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]