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The map label for this gene is moaC

Identifier: 21241854

GI number: 21241854

Start: 1251217

End: 1251714

Strand: Direct

Name: moaC

Synonym: XAC1098

Alternate gene names: 21241854

Gene position: 1251217-1251714 (Clockwise)

Preceding gene: 21241853

Following gene: 21241855

Centisome position: 24.18

GC content: 64.46

Gene sequence:

>498_bases
ATGCCTGCAAACTCCCGCTCCGCCCGCCTGACCCACCTCGACGATGCCGGGCTTCCCACCATGGTGGATGTCTCGGACAA
GGCGGTTACCGCCCGTAGCGCCACTGCGGAAAGCCGCGTGCGCTTTCCGGCTGCCGTAGCCGCACAGTTGCGCGCCAATG
GCTTGCGTAGCGCCAAGGGCGGCATCGTGGAGACGGCGGTGATTGCCGGCACCATGGCGGTCAAGCGCACGCACGAATTG
ATTCCGTTCTGCCATCCGCTACCGATCGATGCCTGCCGTTTCGGGATCGACTGGGCGGGCGAACAGGTGCTGGACATCCG
TTGCACGGTGCGCTGCGTGCATCGCACCGGGGTGGAAATGGAAGCGCTCACCGGGGCCAGCGTTGCCGCATTGACGATCT
ACGACATGTGCAAGGCGTTGTCGCACAGCATGAGCATTGGTCCGACCAAATTGGTGTCCAAGCGCGGCGGCAAGCGCGAC
ATCGGAGCGGCACAATGA

Upstream 100 bases:

>100_bases
GTGGCGAAACGAGCCTGTTGGATGGCAGCCGCTGTTCCACCAAGGCACCCTGTTCACCGAGAATGCCGCATCCTGATGGC
CTGTCTTCGCGTCGCTTCCC

Downstream 100 bases:

>100_bases
CCGCCACGGTGACGGTGCTGTATTTCGCCAGCCTGCGCGAGGCCGCAGGCATTGCCGACGAGCGTGTGCAGACCGGCGCG
CAGGATCTGCGCGGCCTGTA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MPANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHEL
IPFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRD
IGAAQ

Sequences:

>Translated_165_residues
MPANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHEL
IPFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRD
IGAAQ
>Mature_164_residues
PANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHELI
PFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRDI
GAAQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=48.6842105263158, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=40.3973509933775, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=46.4516129032258, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=48.5915492957746, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_XANAC (Q8PNH0)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641436.1
- ProteinModelPortal:   Q8PNH0
- SMR:   Q8PNH0
- GeneID:   1155169
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1098
- NMPDR:   fig|190486.1.peg.1080
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   XAXO190486:XAC1098-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17438; Mature: 17307

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: ACT_SITE 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKG
CCCCCCCCEEEECCCCCCCEEEECCCCEEEHHCCCHHHHHCCHHHHHHHHHHCCCCCCCC
GIVETAVIAGTMAVKRTHELIPFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEHHHHEEEHHHCCCEE
EALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRDIGAAQ
EHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PANSRSARLTHLDDAGLPTMVDVSDKAVTARSATAESRVRFPAAVAAQLRANGLRSAKG
CCCCCCCEEEECCCCCCCEEEECCCCEEEHHCCCHHHHHCCHHHHHHHHHHCCCCCCCC
GIVETAVIAGTMAVKRTHELIPFCHPLPIDACRFGIDWAGEQVLDIRCTVRCVHRTGVEM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEHHHHEEEHHHCCCEE
EALTGASVAALTIYDMCKALSHSMSIGPTKLVSKRGGKRDIGAAQ
EHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217