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The map label for this gene is kdkA

Identifier: 21241851

GI number: 21241851

Start: 1248288

End: 1249037

Strand: Direct

Name: kdkA

Synonym: XAC1095

Alternate gene names: 21241851

Gene position: 1248288-1249037 (Clockwise)

Preceding gene: 21241849

Following gene: 21241852

Centisome position: 24.12

GC content: 67.47

Gene sequence:

>750_bases
ATGGTTTCTTTCGATGCCACCGAAGCGCTGGCGCCGTACCGCGAAGGTCGCGGTTATGGCGCCATTCTGTTCGACCGCGA
ACGGCTGCGGCAAGCCGATGCCAGCCTGTTTTCGCCGCAATCGTGGGGCGACAGGGCGCGTCCGGTGGATGCAGGCGGGC
GTGGCGGCGCGTGGTTCGTGGATGCGCCATTCGGCCATAGCGTGTTGCGGCAGTACCTGCGCGGCGGCATGGCCGCACGC
GTGAGCCGCGATCGCTACCTGTGGAAAGGGGCGGGGCGCACGCGCAGTTTTGCCGAGTTCCGGCTGATGCGTGAACTGAT
CAAACGCAAGTTGCCGGTGCCGCGTCCGTTGGCTGCCTGCTACCTGCGCGAAGGCCTGGGTTATCGCGCTGCGCTGTTGA
TGGAGCGGCTGGAAAACGTGCGCTCGTTGGCCGAGCACGCCCAGGTGGCCGGACGCGGTGCGCCGTGGGAGGCGACCGGC
CAGCTGATCGCACGCTTCCATCGCGCTGGCCTGGATCATGCCGATCTCAACGCGCACAACATCCTGTTCGATGCCGGCGG
GCATGGCTGGCTGATCGACTTCGACCGCGGCGTGCTGCGCATTCCGGCCACGCGCTGGCGCGAGCGCAACCTCAAGCGGC
TGCATCGCTCGCTGTTGAAGCTGCGCGGTAACCGCAGCCGCGAGGACGTCGACAAGGACTATGCGCGCCTGCATCGCGCC
TACGAACTGGCCTGGGGCCGGGGCTACTGA

Upstream 100 bases:

>100_bases
CGTACCAGTGGCACCACGTGCGTGACATCGCCCAGGGCGGACAAGCGCAGCAAACACAGCGATGCGGGCGTTACAGCCAT
GGTGTTGTTAGACTCGATAG

Downstream 100 bases:

>100_bases
TGGACTGGGCCTTGCGGGTGCAGGGAGTCGGCAATGCGTCGGCGGTGGCGCTTGGCTCGCCGATGGCCACGCTCGAGCGC
GCCGGTGCGCCCTGGCTGAC

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFVDAPFGHSVLRQYLRGGMAAR
VSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATG
QLIARFHRAGLDHADLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRA
YELAWGRGY

Sequences:

>Translated_249_residues
MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFVDAPFGHSVLRQYLRGGMAAR
VSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATG
QLIARFHRAGLDHADLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRA
YELAWGRGY
>Mature_249_residues
MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFVDAPFGHSVLRQYLRGGMAAR
VSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATG
QLIARFHRAGLDHADLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRA
YELAWGRGY

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDKA_XANAC (Q8PNH3)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641433.1
- GeneID:   1155166
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1095
- NMPDR:   fig|190486.1.peg.1077
- HOGENOM:   HBG353234
- OMA:   VYHADLN
- ProtClustDB:   PRK01723
- BioCyc:   XAXO190486:XAC1095-MONOMER
- HAMAP:   MF_00521
- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440

Pfam domain/function: PF06293 Kdo; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 28436; Mature: 28436

Theoretical pI: Translated: 11.26; Mature: 11.26

Prosite motif: NA

Important sites: ACT_SITE 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFV
CCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
DAPFGHSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAAC
ECCCCHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
YLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATGQLIARFHRAGLDHADLNAHN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCE
ILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRA
EEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YELAWGRGY
HHHHCCCCC
>Mature Secondary Structure
MVSFDATEALAPYREGRGYGAILFDRERLRQADASLFSPQSWGDRARPVDAGGRGGAWFV
CCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
DAPFGHSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAAC
ECCCCHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
YLREGLGYRAALLMERLENVRSLAEHAQVAGRGAPWEATGQLIARFHRAGLDHADLNAHN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCE
ILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSREDVDKDYARLHRA
EEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YELAWGRGY
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217