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The map label for this gene is drb0080 [H]

Identifier: 21241127

GI number: 21241127

Start: 420943

End: 421710

Strand: Direct

Name: drb0080 [H]

Synonym: XAC0353

Alternate gene names: 21241127

Gene position: 420943-421710 (Clockwise)

Preceding gene: 21241126

Following gene: 21241128

Centisome position: 8.13

GC content: 64.19

Gene sequence:

>768_bases
ATGAATTTGCAGAACAAGACGATCGTGGTGACCGGCGTGGCGTCGGGCATTGGCGCGGAGGTCGCACGGCTGGCACGGTT
TCATGGCGCCAAGGTGATCGGGGTCGATCGCACGCCCGTGCAGATGACCCTGCACGGCTTTCATCAGGCCGATCTTGGCG
ACCCGGCGTCCATCGATGCCCTGGTGAAGGCGTTGCCGAACCAGATCGATGCGTTGGCGAATATTGCCGGCGTGCCCGGC
ACCGCGCCGCTGGATGTGGTGGCGCGAGTGAACTATCTGGGCTTGCGCCATCTGACCCAGGGGCTGCTGCCGCGCATCGT
GTCGGGCGGTTCCATCATCAATGTGGCCTCGATCCTGGGCGCCGAATGGCCGCAGCGTCTGGACCTGCACAAGCAGCTGG
CGGCAACCGACAGCTTCGAAAGCGGCAGCGCGTGGCTGGCGGCGCATCCGGTGGCGCACGACACCTGCTACCAATACTTC
AAAGAGGCCTTGATCGTGTGGACCTTGCTGCAATCGCGGCCCTGGTTCGCCGACCACGGCGTGCGCGTGAACAACGTATC
TCCGGGCCCGGTGTTTACCCCAATCCTGGGCGATTTTGCTGCCATGCTCGGCGAGGAACGCGTCAAGGCAGACGCCAAGC
GCATGACCCGCCCGGCGTATGCCGATGAAGTGGCCGAGGGCATCGTGTTTCTCGCATCCGACGCAGCTCGCTGGATCAAC
GGCATCACCCTGCCGATCGATGGCGGGCTGGCTTCCACAACGCTGTAA

Upstream 100 bases:

>100_bases
ACCGGTGGAGGTCAGGAATGCCGCGTCCGGCAACAACGTCAATTTCGAGTATGTCCATGTGTTCTAGCGCCGGCACGGCT
GGCTCCTTTGGAGGATGGCG

Downstream 100 bases:

>100_bases
TCCCCACACGTTTTTAGCAGGAGGCTAGACCATGAATGCTCTTACCAGCGCAACAGCCGCTGCGACCGACACGCCCGCGT
GGCATGGCTGCATCTTCAAT

Product: 3-alpha-hydroxysteroid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNLQNKTIVVTGVASGIGAEVARLARFHGAKVIGVDRTPVQMTLHGFHQADLGDPASIDALVKALPNQIDALANIAGVPG
TAPLDVVARVNYLGLRHLTQGLLPRIVSGGSIINVASILGAEWPQRLDLHKQLAATDSFESGSAWLAAHPVAHDTCYQYF
KEALIVWTLLQSRPWFADHGVRVNNVSPGPVFTPILGDFAAMLGEERVKADAKRMTRPAYADEVAEGIVFLASDAARWIN
GITLPIDGGLASTTL

Sequences:

>Translated_255_residues
MNLQNKTIVVTGVASGIGAEVARLARFHGAKVIGVDRTPVQMTLHGFHQADLGDPASIDALVKALPNQIDALANIAGVPG
TAPLDVVARVNYLGLRHLTQGLLPRIVSGGSIINVASILGAEWPQRLDLHKQLAATDSFESGSAWLAAHPVAHDTCYQYF
KEALIVWTLLQSRPWFADHGVRVNNVSPGPVFTPILGDFAAMLGEERVKADAKRMTRPAYADEVAEGIVFLASDAARWIN
GITLPIDGGLASTTL
>Mature_255_residues
MNLQNKTIVVTGVASGIGAEVARLARFHGAKVIGVDRTPVQMTLHGFHQADLGDPASIDALVKALPNQIDALANIAGVPG
TAPLDVVARVNYLGLRHLTQGLLPRIVSGGSIINVASILGAEWPQRLDLHKQLAATDSFESGSAWLAAHPVAHDTCYQYF
KEALIVWTLLQSRPWFADHGVRVNNVSPGPVFTPILGDFAAMLGEERVKADAKRMTRPAYADEVAEGIVFLASDAARWIN
GITLPIDGGLASTTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27137; Mature: 27137

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQNKTIVVTGVASGIGAEVARLARFHGAKVIGVDRTPVQMTLHGFHQADLGDPASIDA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHCCCCCCHHHHH
LVKALPNQIDALANIAGVPGTAPLDVVARVNYLGLRHLTQGLLPRIVSGGSIINVASILG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AEWPQRLDLHKQLAATDSFESGSAWLAAHPVAHDTCYQYFKEALIVWTLLQSRPWFADHG
CCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VRVNNVSPGPVFTPILGDFAAMLGEERVKADAKRMTRPAYADEVAEGIVFLASDAARWIN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHC
GITLPIDGGLASTTL
CEEEEECCCCCCCCC
>Mature Secondary Structure
MNLQNKTIVVTGVASGIGAEVARLARFHGAKVIGVDRTPVQMTLHGFHQADLGDPASIDA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHCCCCCCHHHHH
LVKALPNQIDALANIAGVPGTAPLDVVARVNYLGLRHLTQGLLPRIVSGGSIINVASILG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AEWPQRLDLHKQLAATDSFESGSAWLAAHPVAHDTCYQYFKEALIVWTLLQSRPWFADHG
CCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VRVNNVSPGPVFTPILGDFAAMLGEERVKADAKRMTRPAYADEVAEGIVFLASDAARWIN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHC
GITLPIDGGLASTTL
CEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3313281; 11157954; 12597275 [H]