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The map label for this gene is atpE

Identifier: 21226885

GI number: 21226885

Start: 936136

End: 936687

Strand: Reverse

Name: atpE

Synonym: MM_0783

Alternate gene names: 21226885

Gene position: 936687-936136 (Counterclockwise)

Preceding gene: 21226886

Following gene: 21226884

Centisome position: 22.87

GC content: 41.67

Gene sequence:

>552_bases
ATGGGACTAGAGATCGTTGTAAAAGACATCCAAGAGGGTGCAAGAGCTGAGGTTTCCCGTATTAAAGCCGAAGGCGATGC
AAAGGCCTCCGAGATAATTAATGAAGCTAAAGAAATTCAGAAGAAGACGCTCGGAGACAGCCTTGCCAAGGCGGAAGAGG
ACCTCCAAAGTCTGCACCAGCAGGTCATATCAAGTGCAAACCTGGAAGTTAAAAGAATTACGCTTAACAAGCGTAAGGAA
CTTCTAGATACCGTTTATAACCAGACAGTTGAAAATATTAAGTCAATGCCGGCATCCAAAAAAGAAGAGCTGTTAAAAAG
TATTCTCGACAAGCATGAAGCTAGCGGCGCTAGAGCTTATTCTTCTAAGGAGTCAGAAGAGCTTGTTAAGAAGTTAACTT
CTCTATCTTATGCTGGCAATATAGATTCTATTGGCGGAATTGTTCTGGAAAACGAGGACAGGACAGTCAGGTTAGATTTC
ACATACGATTCAATCCTGAAAAGCGTTTATGAACGTTCATTGAAGCAGATATCTGATATATTATACGGGTGA

Upstream 100 bases:

>100_bases
TCTAAGTTCCCCTTAGGTATCGTTGCACTCTAAGCAGCTTAGAGTTTTGCTCTAGGCTTTAGAGCACTTTTTTGCTCTAA
ATTTATTTGGAGGTGTAAGC

Downstream 100 bases:

>100_bases
TGTTCGATGCGGCTTTTGGAGAATCTCTGGGGGAAAAAACCCTCACGAAAATCCGATAAAAAGAAAAAGGGCAGTTCAAA
CTATGCTTATGCCGTAACCC

Product: V-type ATP synthase subunit E

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit E

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MGLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQQVISSANLEVKRITLNKRKE
LLDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAYSSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDF
TYDSILKSVYERSLKQISDILYG

Sequences:

>Translated_183_residues
MGLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQQVISSANLEVKRITLNKRKE
LLDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAYSSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDF
TYDSILKSVYERSLKQISDILYG
>Mature_182_residues
GLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQQVISSANLEVKRITLNKRKEL
LDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAYSSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDFT
YDSILKSVYERSLKQISDILYG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1390

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase E subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATE_METMA (Q60183)

Other databases:

- EMBL:   U47274
- EMBL:   AE008384
- PIR:   T45104
- RefSeq:   NP_632807.1
- ProteinModelPortal:   Q60183
- GeneID:   1479125
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0783
- NMPDR:   fig|192952.1.peg.783
- HOGENOM:   HBG732751
- OMA:   RVRVNNT
- ProtClustDB:   PRK02292
- BioCyc:   MMAZ192952:MM0783-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00311
- InterPro:   IPR002842

Pfam domain/function: PF01991 vATP-synt_E

EC number: 3.6.3.14

Molecular weight: Translated: 20386; Mature: 20255

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQ
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVISSANLEVKRITLNKRKELLDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAY
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHH
SSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDFTYDSILKSVYERSLKQISDI
CCCHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LYG
HCC
>Mature Secondary Structure 
GLEIVVKDIQEGARAEVSRIKAEGDAKASEIINEAKEIQKKTLGDSLAKAEEDLQSLHQ
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVISSANLEVKRITLNKRKELLDTVYNQTVENIKSMPASKKEELLKSILDKHEASGARAY
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHH
SSKESEELVKKLTSLSYAGNIDSIGGIVLENEDRTVRLDFTYDSILKSVYERSLKQISDI
CCCHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LYG
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8702544; 12125824