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The map label for this gene is yhhG [C]

Identifier: 21226768

GI number: 21226768

Start: 799088

End: 799528

Strand: Direct

Name: yhhG [C]

Synonym: MM_0666

Alternate gene names: 21226768

Gene position: 799088-799528 (Clockwise)

Preceding gene: 21226766

Following gene: 21226776

Centisome position: 19.51

GC content: 41.04

Gene sequence:

>441_bases
ATGGAAACAGAACTTATGAGGATAGGGGTTTCCCTTCCTGATACCCTTCTTGGTAAATTTGATGAGATTATCGAAAAAAG
AGGTTATTCTTCCCGCTCGGAAGCCATAAGGGACTCCATCAGGAGTTATATTTCCTACAACGAGTGGATGGGTAACATTA
AAGGCCATCATGTAGGAACGATTGTGATTATTTACGACCATACACAGCGCGGCCTTTCAAATGTCCTGACAGATATACAG
CACCATTATTCTCACCTGATAAGGTCTTCAATTCATATCTATCCTGATCGTGAAGACTGTTTCGAGATAGTGGTCCTGGA
AGGAGAAGGTAAAGAAATTACCGAACTTGCTGAAGCTATAATGGCGCTCAAAGGAGTGAAACTCTCAAAGCTAATAACCA
CAGAATCAAATGAAACGGATGAACCTTCCATCGTAATCTAA

Upstream 100 bases:

>100_bases
TTATATTAATCTTTAAGTGAATTAAACATATATAGTAATACTTACAATTATCAAAGTAATATCATACCAGCAAATGTGAA
ATTGCCTGGCGGGTGGTACT

Downstream 100 bases:

>100_bases
ATCAACACATATAAATCAATATATAAATCAACATATATAAATTAAAATATATAAATAAGTGTGTATAAATTGACGCGTAT
TAATCAACACAGGGAGCCTT

Product: nickel responsive regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
METELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHHVGTIVIIYDHTQRGLSNVLTDIQ
HHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEAIMALKGVKLSKLITTESNETDEPSIVI

Sequences:

>Translated_146_residues
METELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHHVGTIVIIYDHTQRGLSNVLTDIQ
HHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEAIMALKGVKLSKLITTESNETDEPSIVI
>Mature_146_residues
METELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHHVGTIVIIYDHTQRGLSNVLTDIQ
HHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEAIMALKGVKLSKLITTESNETDEPSIVI

Specific function: Transcriptional regulator (Potential)

COG id: COG0864

COG function: function code K; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory CopG/NikR family

Homologues:

Organism=Escherichia coli, GI1789892, Length=107, Percent_Identity=31.7757009345794, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NIKR1_METMA (Q8PZ28)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632690.1
- ProteinModelPortal:   Q8PZ28
- SMR:   Q8PZ28
- GeneID:   1479008
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0666
- NMPDR:   fig|192952.1.peg.666
- HOGENOM:   HBG646378
- OMA:   HIQHENH
- ProtClustDB:   PRK01002
- BioCyc:   MMAZ192952:MM0666-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00476
- InterPro:   IPR013321
- InterPro:   IPR002145
- InterPro:   IPR022988
- InterPro:   IPR010985
- InterPro:   IPR014864
- Gene3D:   G3DSA:1.10.1220.10
- Gene3D:   G3DSA:3.30.70.1150

Pfam domain/function: PF08753 NikR_C; PF01402 RHH_1; SSF47598 Met_repress_like

EC number: NA

Molecular weight: Translated: 16601; Mature: 16601

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHHVGT
CCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
IVIIYDHTQRGLSNVLTDIQHHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEAI
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEEECCCCHHHHHHHHH
MALKGVKLSKLITTESNETDEPSIVI
HHHCCCHHHHEEECCCCCCCCCCEEC
>Mature Secondary Structure
METELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHHVGT
CCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
IVIIYDHTQRGLSNVLTDIQHHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEAI
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEEECCCCHHHHHHHHH
MALKGVKLSKLITTESNETDEPSIVI
HHHCCCHHHHEEECCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824