BacMap

Definition	Methanosarcina mazei Go1 chromosome, complete genome.
Accession	NC_003901
Length	4,096,345

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The map label for this gene is abcA [H]

Identifier: 21226758

GI number: 21226758

Start: 786166

End: 787431

Strand: Reverse

Name: abcA [H]

Synonym: MM_0656

Alternate gene names: 21226758

Gene position: 787431-786166 (Counterclockwise)

Preceding gene: 21226759

Following gene: 21226756

Centisome position: 19.22

GC content: 37.28

Gene sequence:

>1266_bases
ATGACAGCGTCAAAAAAGGAAGAACCGATAATTGAAGTAAAACATCTATCTAAACAGTACAATATCGGCGTGGACACGAC
TTACAAGACTCTATCTGAAAGCTTTACTTCTGCTGTGAAGCAGCCAATAAAGACGCTAAAAGACTTTCGCAGGCAAAATG
AGACTTTCTGGGCTCTCAAGGACGTGAATTTCGAGGTCGAGCGTGGAGAAGTTCTTGGTATTATCGGCAGAAATGGTGCA
GGCAAGAGTACTCTTCTTAAAATCCTCTCACGTATTACCTCCCCGACACAGGGCGAGGTCAGGATGCGCGGCCGAGTTGG
TAGCCTTCTTGAGGTTGGCACCGGTTTCCACCCTGAGCTTTCCGGTCGGGAGAATATCTATTTTAACGGTTCTATCCTCG
GCATGAAGAAGAAAGAGATAGACGAGAAATTTGACGAGATTGTGAAGTTTTCAGGAGTCGAAAAGTTTCTGGATACACCA
GTTAAACGGTATTCAAGCGGGATGCAGGTTCGGCTTGCTTTTTCTGTCGCAGCGAATCTTGACCCTGAAATTCTTGTAGT
GGACGAGGTTCTTGCTGTTGGTGATGCAGCATTTCAGGAAAAGTGTCTTGGGAAGATGAGTGAGGTTGTTGAAAGTGGAA
GGACGGTACTGTTTGTTAGTCATAATATGGGAGCTGTACAGAACTTGTGCCAACGGTGTATTCTTTTAAATGAAGGGCAC
TTAATAACGAATGGTAAAACTGCTGATGTAATTAATTATTATCTAAATACAGGTTTACAAGTGGCTGATAAATCTATTTT
CAAGAGAGATGTTTCTAAGAAAAAATTATTCTTTACTGATATAAATTTATATAATACAAAAGGTGAGATTAGAACTAAAT
TTACATCAGATGAAAATATTCTAATTGCGATTAACTATAACTTAAATGTCCAACTTACTGGTGCTCAAATAACTTTTGAA
ATATTTGATCAGAATGGAATCTGTATTCTCTCTTCTACAAATTTTGATTCAAACATTAAAATGCGTACGCTTTCTCAAAA
ACCTGGAGAATATATTGCAACATGTCCAATTAATGTCGATTTTTTAAGAAATGGCCTTTATTATATTACGATTAGTTCCT
CGGTTCCAAACATTGAAATTTTAGATATAGTTGAATTCGCAACAAGATTTGAAATCGAATCTCCATTAGATATAACTACT
CTTTTAGGTCAAAGTAGGAAAGGTGTTATTTTTAAGAATTTTGTATGGCAAATTAATCAATATTAA

Upstream 100 bases:

>100_bases
TGTCGGTCTGGGAATCTCAGCTGTATTGACTGTAGTAATATTTGTTAGTGGTATACTTTACCTGAGAAGTACTGAAAAGT
ACTTTGCGGATTTGATTTAA

Downstream 100 bases:

>100_bases
TCAACACTTTAATAAAGTGTAAAAACTTCCTAACAGTTTGTATAAACATAATGAACTAAAGAACAAATTATGCAAATAGG
AACAAGACGCCAATAAATTA

Product: polysaccharide ABC transporter ATP-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTASKKEEPIIEVKHLSKQYNIGVDTTYKTLSESFTSAVKQPIKTLKDFRRQNETFWALKDVNFEVERGEVLGIIGRNGA
GKSTLLKILSRITSPTQGEVRMRGRVGSLLEVGTGFHPELSGRENIYFNGSILGMKKKEIDEKFDEIVKFSGVEKFLDTP
VKRYSSGMQVRLAFSVAANLDPEILVVDEVLAVGDAAFQEKCLGKMSEVVESGRTVLFVSHNMGAVQNLCQRCILLNEGH
LITNGKTADVINYYLNTGLQVADKSIFKRDVSKKKLFFTDINLYNTKGEIRTKFTSDENILIAINYNLNVQLTGAQITFE
IFDQNGICILSSTNFDSNIKMRTLSQKPGEYIATCPINVDFLRNGLYYITISSSVPNIEILDIVEFATRFEIESPLDITT
LLGQSRKGVIFKNFVWQINQY

Sequences:

>Translated_421_residues
MTASKKEEPIIEVKHLSKQYNIGVDTTYKTLSESFTSAVKQPIKTLKDFRRQNETFWALKDVNFEVERGEVLGIIGRNGA
GKSTLLKILSRITSPTQGEVRMRGRVGSLLEVGTGFHPELSGRENIYFNGSILGMKKKEIDEKFDEIVKFSGVEKFLDTP
VKRYSSGMQVRLAFSVAANLDPEILVVDEVLAVGDAAFQEKCLGKMSEVVESGRTVLFVSHNMGAVQNLCQRCILLNEGH
LITNGKTADVINYYLNTGLQVADKSIFKRDVSKKKLFFTDINLYNTKGEIRTKFTSDENILIAINYNLNVQLTGAQITFE
IFDQNGICILSSTNFDSNIKMRTLSQKPGEYIATCPINVDFLRNGLYYITISSSVPNIEILDIVEFATRFEIESPLDITT
LLGQSRKGVIFKNFVWQINQY
>Mature_420_residues
TASKKEEPIIEVKHLSKQYNIGVDTTYKTLSESFTSAVKQPIKTLKDFRRQNETFWALKDVNFEVERGEVLGIIGRNGAG
KSTLLKILSRITSPTQGEVRMRGRVGSLLEVGTGFHPELSGRENIYFNGSILGMKKKEIDEKFDEIVKFSGVEKFLDTPV
KRYSSGMQVRLAFSVAANLDPEILVVDEVLAVGDAAFQEKCLGKMSEVVESGRTVLFVSHNMGAVQNLCQRCILLNEGHL
ITNGKTADVINYYLNTGLQVADKSIFKRDVSKKKLFFTDINLYNTKGEIRTKFTSDENILIAINYNLNVQLTGAQITFEI
FDQNGICILSSTNFDSNIKMRTLSQKPGEYIATCPINVDFLRNGLYYITISSSVPNIEILDIVEFATRFEIESPLDITTL
LGQSRKGVIFKNFVWQINQY

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=201, Percent_Identity=28.3582089552239, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI31657092, Length=223, Percent_Identity=26.457399103139, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI153792144, Length=263, Percent_Identity=25.4752851711027, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI6005701, Length=200, Percent_Identity=28, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI30795238, Length=194, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI27881501, Length=194, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI27477115, Length=196, Percent_Identity=27.5510204081633, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI105990541, Length=185, Percent_Identity=27.5675675675676, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI116734710, Length=233, Percent_Identity=25.3218884120172, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI150417984, Length=184, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI21536376, Length=219, Percent_Identity=25.5707762557078, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI27262624, Length=214, Percent_Identity=24.7663551401869, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27262626, Length=214, Percent_Identity=24.7663551401869, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI47078218, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI73747915, Length=201, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1790467, Length=205, Percent_Identity=27.3170731707317, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789032, Length=217, Percent_Identity=23.963133640553, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87081782, Length=243, Percent_Identity=25.5144032921811, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=223, Percent_Identity=25.5605381165919, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994943, Length=220, Percent_Identity=25, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081709, Length=203, Percent_Identity=24.1379310344828, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=217, Percent_Identity=26.2672811059908, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788450, Length=217, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=223, Percent_Identity=20.627802690583, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787792, Length=223, Percent_Identity=25.1121076233184, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=25.3588516746411, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787089, Length=210, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=25.5813953488372, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787105, Length=231, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082267, Length=192, Percent_Identity=25.5208333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=209, Percent_Identity=23.444976076555, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=198, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789672, Length=214, Percent_Identity=24.2990654205607, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786872, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=215, Percent_Identity=28.3720930232558, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788897, Length=225, Percent_Identity=25.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786563, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788761, Length=199, Percent_Identity=22.1105527638191, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789593, Length=222, Percent_Identity=23.4234234234234, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788506, Length=231, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081834, Length=184, Percent_Identity=27.7173913043478, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=203, Percent_Identity=29.064039408867, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565586, Length=208, Percent_Identity=25.9615384615385, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983510, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=218, Percent_Identity=24.7706422018349, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17539902, Length=241, Percent_Identity=26.5560165975104, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=221, Percent_Identity=24.8868778280543, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=189, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=187, Percent_Identity=26.7379679144385, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221500365, Length=196, Percent_Identity=27.0408163265306, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI116007184, Length=196, Percent_Identity=27.0408163265306, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24666092, Length=206, Percent_Identity=26.2135922330097, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221512771, Length=206, Percent_Identity=24.7572815533981, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643674, Length=212, Percent_Identity=25.4716981132075, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650855, Length=238, Percent_Identity=25.6302521008403, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650853, Length=230, Percent_Identity=25.6521739130435, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281362751, Length=215, Percent_Identity=26.9767441860465, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573571, Length=232, Percent_Identity=21.9827586206897, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573573, Length=232, Percent_Identity=21.9827586206897, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648314, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85726357, Length=229, Percent_Identity=25.3275109170306, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582014, Length=212, Percent_Identity=27.3584905660377, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582012, Length=212, Percent_Identity=27.3584905660377, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 47332; Mature: 47201

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASKKEEPIIEVKHLSKQYNIGVDTTYKTLSESFTSAVKQPIKTLKDFRRQNETFWALK
CCCCCCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
DVNFEVERGEVLGIIGRNGAGKSTLLKILSRITSPTQGEVRMRGRVGSLLEVGTGFHPEL
ECCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCC
SGRENIYFNGSILGMKKKEIDEKFDEIVKFSGVEKFLDTPVKRYSSGMQVRLAFSVAANL
CCCCEEEECCEEECCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEEEEEECCC
DPEILVVDEVLAVGDAAFQEKCLGKMSEVVESGRTVLFVSHNMGAVQNLCQRCILLNEGH
CCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHEEECCCE
LITNGKTADVINYYLNTGLQVADKSIFKRDVSKKKLFFTDINLYNTKGEIRTKFTSDENI
EEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEECCCCE
LIAINYNLNVQLTGAQITFEIFDQNGICILSSTNFDSNIKMRTLSQKPGEYIATCPINVD
EEEEEECEEEEEECCEEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCHH
FLRNGLYYITISSSVPNIEILDIVEFATRFEIESPLDITTLLGQSRKGVIFKNFVWQINQ
HHHCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEECC
Y
C
>Mature Secondary Structure 
TASKKEEPIIEVKHLSKQYNIGVDTTYKTLSESFTSAVKQPIKTLKDFRRQNETFWALK
CCCCCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
DVNFEVERGEVLGIIGRNGAGKSTLLKILSRITSPTQGEVRMRGRVGSLLEVGTGFHPEL
ECCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCC
SGRENIYFNGSILGMKKKEIDEKFDEIVKFSGVEKFLDTPVKRYSSGMQVRLAFSVAANL
CCCCEEEECCEEECCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEEEEEECCC
DPEILVVDEVLAVGDAAFQEKCLGKMSEVVESGRTVLFVSHNMGAVQNLCQRCILLNEGH
CCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHEEECCCE
LITNGKTADVINYYLNTGLQVADKSIFKRDVSKKKLFFTDINLYNTKGEIRTKFTSDENI
EEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEECCCCE
LIAINYNLNVQLTGAQITFEIFDQNGICILSSTNFDSNIKMRTLSQKPGEYIATCPINVD
EEEEEECEEEEEECCEEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCHH
FLRNGLYYITISSSVPNIEILDIVEFATRFEIESPLDITTLLGQSRKGVIFKNFVWQINQ
HHHCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEECC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]