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The map label for this gene is rpoE1 [H]

Identifier: 21226698

GI number: 21226698

Start: 727461

End: 728045

Strand: Direct

Name: rpoE1 [H]

Synonym: MM_0596

Alternate gene names: 21226698

Gene position: 727461-728045 (Clockwise)

Preceding gene: 21226697

Following gene: 21226699

Centisome position: 17.76

GC content: 47.35

Gene sequence:

>585_bases
ATGTATAAATTAATGAAACTCGTTGATACGGTTCGTATCCCTCCTACCCTTCTCGGGGAAGAAATAATGCCCACTATTAA
AAATGCATTAAGGGAGAAACTTGAGGGGCAGGTAGACAAGAAACTTGGCTCTCTCGTTGCTGTTTACAATATTGACGAGG
TCGGAGAAGGACATATCCTTGTCGGAGACGGGGCTGTGTACTACGATGTGACATTTGAAGCGATAATGTTCTACCCTGAT
CTCCAGGAAATCATAGAAGGCGAAGTCGTTGAGGCTGTAGGCTTCGGAGTTTTCATAGGGATGGGACCAATGGACGGGCT
GCTACACGTCAGCCAGATCACTGATGATTTTATTTCCTATGATGCGAAAAATGCAAGGCTTGTTACTAAAAGCGGAGGCA
AGTCAATTGCCGAAGGCGACCATGTAAGGGCCAGAATTGTCGCGGTCAGCATTAATGAGAGGGAGCCGAAAGAAAGCAAG
ATAGGACTTACCATGCGCCAGACAGCCCTTGGAAAACTTCAGTGGCTCGAAGAAGCCCGCAGAAAGAAACAGCCTCAAGA
AACCCCAGGTGAAGAGGCTGCCTGA

Upstream 100 bases:

>100_bases
ATATCCCTGCGCCAGAAAAACAAACTGGATTTTGTTTGAAAAACCCACCGGAGATTCCGGGGCAGCAGTTCGATTGATTA
AGTTTACGGGTGATTAGCAG

Downstream 100 bases:

>100_bases
GTAAAAAAAGGCAAAAGAGAGGATTGCAATGCCAGAAAAAGTCTGTCGACACTGCCTGAGGGTTCTCGAAGGGCAAACAT
GTCCTGTTTGCGGAACTTCA

Product: DNA-directed RNA polymerase subunit E'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MYKLMKLVDTVRIPPTLLGEEIMPTIKNALREKLEGQVDKKLGSLVAVYNIDEVGEGHILVGDGAVYYDVTFEAIMFYPD
LQEIIEGEVVEAVGFGVFIGMGPMDGLLHVSQITDDFISYDAKNARLVTKSGGKSIAEGDHVRARIVAVSINEREPKESK
IGLTMRQTALGKLQWLEEARRKKQPQETPGEEAA

Sequences:

>Translated_194_residues
MYKLMKLVDTVRIPPTLLGEEIMPTIKNALREKLEGQVDKKLGSLVAVYNIDEVGEGHILVGDGAVYYDVTFEAIMFYPD
LQEIIEGEVVEAVGFGVFIGMGPMDGLLHVSQITDDFISYDAKNARLVTKSGGKSIAEGDHVRARIVAVSINEREPKESK
IGLTMRQTALGKLQWLEEARRKKQPQETPGEEAA
>Mature_194_residues
MYKLMKLVDTVRIPPTLLGEEIMPTIKNALREKLEGQVDKKLGSLVAVYNIDEVGEGHILVGDGAVYYDVTFEAIMFYPD
LQEIIEGEVVEAVGFGVFIGMGPMDGLLHVSQITDDFISYDAKNARLVTKSGGKSIAEGDHVRARIVAVSINEREPKESK
IGLTMRQTALGKLQWLEEARRKKQPQETPGEEAA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1095

COG function: function code K; DNA-directed RNA polymerase, subunit E'

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI24475814, Length=162, Percent_Identity=27.1604938271605, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI65301161, Length=162, Percent_Identity=27.1604938271605, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI4505947, Length=157, Percent_Identity=26.7515923566879, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510349, Length=157, Percent_Identity=26.7515923566879, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322705, Length=168, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647020, Length=153, Percent_Identity=26.797385620915, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR005576
- InterPro:   IPR004519 [H]

Pfam domain/function: PF03876 RNA_pol_Rpb7_N; PF00575 S1 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 21432; Mature: 21432

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLMKLVDTVRIPPTLLGEEIMPTIKNALREKLEGQVDKKLGSLVAVYNIDEVGEGHIL
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEE
VGDGAVYYDVTFEAIMFYPDLQEIIEGEVVEAVGFGVFIGMGPMDGLLHVSQITDDFISY
EECCEEEEEEEEEEEEECCCHHHHHCCHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHC
DAKNARLVTKSGGKSIAEGDHVRARIVAVSINEREPKESKIGLTMRQTALGKLQWLEEAR
CCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHH
RKKQPQETPGEEAA
HHCCCCCCCCCCCC
>Mature Secondary Structure
MYKLMKLVDTVRIPPTLLGEEIMPTIKNALREKLEGQVDKKLGSLVAVYNIDEVGEGHIL
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEE
VGDGAVYYDVTFEAIMFYPDLQEIIEGEVVEAVGFGVFIGMGPMDGLLHVSQITDDFISY
EECCEEEEEEEEEEEEECCCHHHHHCCHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHC
DAKNARLVTKSGGKSIAEGDHVRARIVAVSINEREPKESKIGLTMRQTALGKLQWLEEAR
CCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHH
RKKQPQETPGEEAA
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]