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The map label for this gene is yeeO [C]

Identifier: 21226446

GI number: 21226446

Start: 451470

End: 452906

Strand: Reverse

Name: yeeO [C]

Synonym: MM_0344

Alternate gene names: 21226446

Gene position: 452906-451470 (Counterclockwise)

Preceding gene: 21226447

Following gene: 21226445

Centisome position: 11.06

GC content: 47.39

Gene sequence:

>1437_bases
ATGGAGCTTAAAACAGCAGCAGATTCAAACTTTTCTGAATCTGAAGAAAGCCCGGAAACTAAAGGCATAAGAATCCTTGA
GGGAGATCCGAAAAAAGCAATCATTAAACTTGCAGTCCCTATGATTGTTGCAATGTCCGTTCAGACTCTTTACCAGCTCA
TAGACACCTTCTGGGTCTCGGGGCTCGGAGCAGACGCACTTGCTGCAATGGGTTTCGTATTTCCATTTTATTTCATAAGC
ATGGCTTTATCCAACGGCCTGGGCATAGGAGGAGGAGCAGCCATCTCCCGAAAAATCGGAGCGCGGGATAAGGCAGGAGC
AGACAACGTAGCCGTACATACGATTATAATAATGATGCTGCTCGTTCTCATATTTACCATACCTTTCTATGTTTTTGCCC
CTCATATATTCTCACTTGTAGGAGCAGGGAAAACAACCGATCTTGCGGTAGCTTATGCGAGGGTAATATTTCTCGGGAGC
ATAGTGATCTTTTTTACTAACGTAGCGAACTCTATCCTCAGGTCCGAAGGGGATTCAAAGCGGGCAATGTACGCAATGGT
CCTCGGGGCAGCCCTGAATATCGTTATTGACCCCATTTTCATATACACCTTTAAAATGGGGATTGCAGGTGCAGCCTGGG
CGACACTGCTTTCTCTTGCGGTCTCCTCAGCCATGATGCTGAACTGGCTCTTTTTCAAAAAGGACACTTTCGTTTCCTTT
GACTTTAAAGACTTCAGCTTTGAGAAAAGCATAATAAACGACATATTCCGGATTGCAGTCCCGGCTTCCGCACAGCAGCT
TTCAATGTCGTTATCCATGCTCGTCCTCAACCTGATTATTGTGAACGTGAGCAGCACTGACGGAGTTGCAGTTTACTCCA
CAGGCTGGCGTGTTGCTACAATTGCAATTGCCCCACTTGTAGGTATAGCAACTGCAGTAGTTTCTGTTTCCGGAGCCGCC
TTCGGGGCGAAAGACTTTGAAAAAGCAAAAACAGCACATACCTATGCAGTGAAAGTCGGACTCCTTATAGAAGGCGGGGT
TGCTGCATTTACTTTTATATTCGCCCCACAGATTGCAGCCGTTTTCACGCAGACGGAAGAAGCCGCTCACATAGCTCCGG
ATCTTATCCAGTTCCTGCGCATAATCTGCATCTTCTATCCAACAGTTTCTCTCGGAATGCTCTCGACATCCCTATTCCAG
GGGGCTGGAAAAGGCTTCAGCGCGCTTACCGCAAATCTCCTGAGAACCATAGTATTTACCCCGCTCTTTGCAGCTTTTTT
TGCCTTCAATCTGAATATGGGCCAGGTAGGTGCCTGGTGGGGGATCGTTGCAGGCAACGCTATTGGGGCTGGAGTGGTCT
ATGTCTGGGTAAAGCTTTATCTCAGTACGATTCTGAAAACAGGGCCCCTGCATAAACCCTTCGAGCAGGGGATTTAA

Upstream 100 bases:

>100_bases
GAAGAATAAATGCTGTTAATTTCGGTGTGTCTTCCCTGTCCCTTGAAAAAATACAGCTCAGGAGAAAAGGTAAAAAGACA
TATTGAAGGGAAGACAGTAA

Downstream 100 bases:

>100_bases
ACTTTTTTGAGCAAATATTTTATAGAAAGAATTCTAATAAATCGTAAATGTTGTACCAAATATTTATATATATGTAGAAG
GTAATAAGTTACCGTCTGCC

Product: putative cation efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MELKTAADSNFSESEESPETKGIRILEGDPKKAIIKLAVPMIVAMSVQTLYQLIDTFWVSGLGADALAAMGFVFPFYFIS
MALSNGLGIGGGAAISRKIGARDKAGADNVAVHTIIIMMLLVLIFTIPFYVFAPHIFSLVGAGKTTDLAVAYARVIFLGS
IVIFFTNVANSILRSEGDSKRAMYAMVLGAALNIVIDPIFIYTFKMGIAGAAWATLLSLAVSSAMMLNWLFFKKDTFVSF
DFKDFSFEKSIINDIFRIAVPASAQQLSMSLSMLVLNLIIVNVSSTDGVAVYSTGWRVATIAIAPLVGIATAVVSVSGAA
FGAKDFEKAKTAHTYAVKVGLLIEGGVAAFTFIFAPQIAAVFTQTEEAAHIAPDLIQFLRIICIFYPTVSLGMLSTSLFQ
GAGKGFSALTANLLRTIVFTPLFAAFFAFNLNMGQVGAWWGIVAGNAIGAGVVYVWVKLYLSTILKTGPLHKPFEQGI

Sequences:

>Translated_478_residues
MELKTAADSNFSESEESPETKGIRILEGDPKKAIIKLAVPMIVAMSVQTLYQLIDTFWVSGLGADALAAMGFVFPFYFIS
MALSNGLGIGGGAAISRKIGARDKAGADNVAVHTIIIMMLLVLIFTIPFYVFAPHIFSLVGAGKTTDLAVAYARVIFLGS
IVIFFTNVANSILRSEGDSKRAMYAMVLGAALNIVIDPIFIYTFKMGIAGAAWATLLSLAVSSAMMLNWLFFKKDTFVSF
DFKDFSFEKSIINDIFRIAVPASAQQLSMSLSMLVLNLIIVNVSSTDGVAVYSTGWRVATIAIAPLVGIATAVVSVSGAA
FGAKDFEKAKTAHTYAVKVGLLIEGGVAAFTFIFAPQIAAVFTQTEEAAHIAPDLIQFLRIICIFYPTVSLGMLSTSLFQ
GAGKGFSALTANLLRTIVFTPLFAAFFAFNLNMGQVGAWWGIVAGNAIGAGVVYVWVKLYLSTILKTGPLHKPFEQGI
>Mature_478_residues
MELKTAADSNFSESEESPETKGIRILEGDPKKAIIKLAVPMIVAMSVQTLYQLIDTFWVSGLGADALAAMGFVFPFYFIS
MALSNGLGIGGGAAISRKIGARDKAGADNVAVHTIIIMMLLVLIFTIPFYVFAPHIFSLVGAGKTTDLAVAYARVIFLGS
IVIFFTNVANSILRSEGDSKRAMYAMVLGAALNIVIDPIFIYTFKMGIAGAAWATLLSLAVSSAMMLNWLFFKKDTFVSF
DFKDFSFEKSIINDIFRIAVPASAQQLSMSLSMLVLNLIIVNVSSTDGVAVYSTGWRVATIAIAPLVGIATAVVSVSGAA
FGAKDFEKAKTAHTYAVKVGLLIEGGVAAFTFIFAPQIAAVFTQTEEAAHIAPDLIQFLRIICIFYPTVSLGMLSTSLFQ
GAGKGFSALTANLLRTIVFTPLFAAFFAFNLNMGQVGAWWGIVAGNAIGAGVVYVWVKLYLSTILKTGPLHKPFEQGI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=437, Percent_Identity=24.0274599542334, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51094; Mature: 51094

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKTAADSNFSESEESPETKGIRILEGDPKKAIIKLAVPMIVAMSVQTLYQLIDTFWVS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGADALAAMGFVFPFYFISMALSNGLGIGGGAAISRKIGARDKAGADNVAVHTIIIMML
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LVLIFTIPFYVFAPHIFSLVGAGKTTDLAVAYARVIFLGSIVIFFTNVANSILRSEGDSK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RAMYAMVLGAALNIVIDPIFIYTFKMGIAGAAWATLLSLAVSSAMMLNWLFFKKDTFVSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEE
DFKDFSFEKSIINDIFRIAVPASAQQLSMSLSMLVLNLIIVNVSSTDGVAVYSTGWRVAT
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEH
IAIAPLVGIATAVVSVSGAAFGAKDFEKAKTAHTYAVKVGLLIEGGVAAFTFIFAPQIAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHH
VFTQTEEAAHIAPDLIQFLRIICIFYPTVSLGMLSTSLFQGAGKGFSALTANLLRTIVFT
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PLFAAFFAFNLNMGQVGAWWGIVAGNAIGAGVVYVWVKLYLSTILKTGPLHKPFEQGI
HHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure
MELKTAADSNFSESEESPETKGIRILEGDPKKAIIKLAVPMIVAMSVQTLYQLIDTFWVS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGADALAAMGFVFPFYFISMALSNGLGIGGGAAISRKIGARDKAGADNVAVHTIIIMML
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LVLIFTIPFYVFAPHIFSLVGAGKTTDLAVAYARVIFLGSIVIFFTNVANSILRSEGDSK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RAMYAMVLGAALNIVIDPIFIYTFKMGIAGAAWATLLSLAVSSAMMLNWLFFKKDTFVSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEE
DFKDFSFEKSIINDIFRIAVPASAQQLSMSLSMLVLNLIIVNVSSTDGVAVYSTGWRVAT
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEH
IAIAPLVGIATAVVSVSGAAFGAKDFEKAKTAHTYAVKVGLLIEGGVAAFTFIFAPQIAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHH
VFTQTEEAAHIAPDLIQFLRIICIFYPTVSLGMLSTSLFQGAGKGFSALTANLLRTIVFT
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
PLFAAFFAFNLNMGQVGAWWGIVAGNAIGAGVVYVWVKLYLSTILKTGPLHKPFEQGI
HHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]