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The map label for this gene is fdnH [C]

Identifier: 21226342

GI number: 21226342

Start: 322783

End: 323169

Strand: Reverse

Name: fdnH [C]

Synonym: MM_0240

Alternate gene names: 21226342

Gene position: 323169-322783 (Counterclockwise)

Preceding gene: 21226343

Following gene: 21226341

Centisome position: 7.89

GC content: 45.48

Gene sequence:

>387_bases
ATGAAAATAAAGATCTGCATCCCTACTGAAAGGATACATAACCCAATTATCTCCGAGTCCATCATAGAAACAGGGATCCT
GCTTAATATTATGGTCGCAAACATTGACTCAACTTACGGAGAACTCATTGCAGACGTTAAAGATTCCAGGTTCGATAAAA
TTAAAAATGCTCTCGAGTCGAGAGGGGCAATCGTTGCAATTCTTGACCGGCCCATCCACAGGGACGAGGAAGAATGTGTT
GAATGCGGAGCCTGCATTTCTGTCTGCCCTATGAATGTTTATGCCTTTGATGAGGACTGGAGCCTCTGCGTGGACGAAAA
GAAATGTATCCAGTGCGGCATGTGCATCAAGATGTGCCCGCACGGGGCTTTAAAGCTGGGAGAATGA

Upstream 100 bases:

>100_bases
ACGGAGTTTCAGCAATGCCGGTGATTGATGCGCAGAAGAAAGTACTCGGAATTATCACAAGCGACAATATAAGCAAGCTC
TTTGCAAGGAGGTACTGAGC

Downstream 100 bases:

>100_bases
AAAACTGAGCCCCAGTTTTTTCATTTCTCTCCTTTTCATTTTTTATTTCCCGTTTATGTCCTTTTTTCTTTTTCTCCTTG
TAGTTTCTTTTATTTCCCTC

Product: ferredoxin

Products: CO2; NADH2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKIKICIPTERIHNPIISESIIETGILLNIMVANIDSTYGELIADVKDSRFDKIKNALESRGAIVAILDRPIHRDEEECV
ECGACISVCPMNVYAFDEDWSLCVDEKKCIQCGMCIKMCPHGALKLGE

Sequences:

>Translated_128_residues
MKIKICIPTERIHNPIISESIIETGILLNIMVANIDSTYGELIADVKDSRFDKIKNALESRGAIVAILDRPIHRDEEECV
ECGACISVCPMNVYAFDEDWSLCVDEKKCIQCGMCIKMCPHGALKLGE
>Mature_128_residues
MKIKICIPTERIHNPIISESIIETGILLNIMVANIDSTYGELIADVKDSRFDKIKNALESRGAIVAILDRPIHRDEEECV
ECGACISVCPMNVYAFDEDWSLCVDEKKCIQCGMCIKMCPHGALKLGE

Specific function: Formate Dehydrogenase Allows E. coli To Use Formate As Major Electron Donor During Anaerobic Respiration, When Nitrate Is Used As Electron Acceptor. The Beta Chain Is An Electron Transfer Unit Containing 4 Cysteine Clusters Involved In The Formation Of Ir

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR018449 [H]

Pfam domain/function: PF00037 Fer4; PF09383 NIL [H]

EC number: NA

Molecular weight: Translated: 14258; Mature: 14258

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
11.7 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
11.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKICIPTERIHNPIISESIIETGILLNIMVANIDSTYGELIADVKDSRFDKIKNALES
CEEEEECCHHHHCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RGAIVAILDRPIHRDEEECVECGACISVCPMNVYAFDEDWSLCVDEKKCIQCGMCIKMCP
CCCEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHCC
HGALKLGE
CCCEECCC
>Mature Secondary Structure
MKIKICIPTERIHNPIISESIIETGILLNIMVANIDSTYGELIADVKDSRFDKIKNALES
CEEEEECCHHHHCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RGAIVAILDRPIHRDEEECVECGACISVCPMNVYAFDEDWSLCVDEKKCIQCGMCIKMCP
CCCEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHCC
HGALKLGE
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD [C]

Specific reaction: formate + NAD = CO2 + NADH2 [C]

General reaction: Oxidoreductases; Acting on the aldehyde or oxo group of donors [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]