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The map label for this gene is recG [H]

Identifier: 21226300

GI number: 21226300

Start: 275374

End: 276738

Strand: Reverse

Name: recG [H]

Synonym: MM_0198

Alternate gene names: 21226300

Gene position: 276738-275374 (Counterclockwise)

Preceding gene: 21226301

Following gene: 21226293

Centisome position: 6.76

GC content: 40.15

Gene sequence:

>1365_bases
ATGAACCCTTTTTTTAAACAAAAGGAATCTGAAACCCTTGAACTGAAAAAATCCACTGCACAATTGAAACCTGCCGTAAT
CTCTATAGTTGCTATACTCAACAAGCATCAGGAAGGCAAATTATACTTTGGAGTTAAGGACGATGGGACAGTTGTGGGGC
AGGAAATTGGGAATGACACTTTGAGAACCATTTCTCAGGCTATTTCAGCGTACATAGAACCAAAAGTCTATCCCGTTATC
CGGCAAGTAACTTTCGAGGGAAAATCTTGCATTGAAGTCGAATTCCAGGGAAATGAAGTACCTTACTTTGCATACGGCAG
AGCTTATATTCGCACTTCTGATGAGGACAAGCCCCTGAGTGTAAAAGAACTTGAGAACCTGATACTCAGGAAGAATAAGG
ACCAATTGAAGTGGGATAGTTCCATTTGCAGGGAAGCAAGTTTAGAAGATATCAGTGAAGAAAAAGTCAGGTCCTTTGTA
AAAGAAGCTGGCAAAGAGTACAAAGGGCTTGAAAATTCCCTGAAAAAATTAAAGCTCGCAAAAGACGGAAATTTAACAAA
TGCCGCAGTCATTCTTTTCGGAAAGAAACCCGAGGATTTTTTCCCTAATGCAAAACTCAGGTGTGCAGTCTTTGCTACAA
ATGACACTTCGTATATCATTGACATGCAGGACTATACAGGTGATCTCTTCTACCTGATAGGTGAGGCTGAAAAATACATC
CTTAAAAACATCCATATTGGAATGCGGCTTGAAGGTCTAAAGAGAATCGACGTCCCTGAAATCTCGAAAGAAGCAATAAG
AGAAGCCATAATAAACGCCTTTTGCCACCGGGACTACTATGAATATGATTCCGTAAATGTAGCCGTATTCAAAAACCGCG
TGGAAATCAGAAACAAAGGTCTCCTTTATGGAGGACTTACCATCGAACAGATCAAGACCGAAATGGTTTCTGAGCGAAGG
AATGAGCTGATAGCTGAAATCTTCCATGAAATTCACTGGATTGAAAAATGGGGCAGAGGAATAAGTCTTATCCTTTCGAT
GGAACCCGACACTGATTTTAAAGAGGTTGGGACTCAGTTTATTGTAACGTTTAAGAGGAAGTATTTTGAGGATAGTGAGG
AAAGAGACGGAGAAAAGGTCGGAGAAAAGGTCGGAGAAAAGGTCGGAGAAACTCTAACCCAAAATCAAGAAGTGATACTC
AGTTTGATAAGAGAAAATTCACGAATTTCAGCCAGGGAACTTTCCGATAGAGTAGGCATTTCTGCAAGAAAAACTGAAGA
AAACATTTCTAAATTAAAGAAAAAGGGTTTACTCAAGAGAATCGGTTCGGCTAGAGGCGGTTACTGGGAAATCATTGAAA
AATGA

Upstream 100 bases:

>100_bases
CGAATATAAAGTCCTCAATTCCATTAATTTCCAAAATCCATACCTTTTATAATACTTGAATATTATCTTAAAGTCATAAG
AATTATTTCAGGACCTGGTT

Downstream 100 bases:

>100_bases
GGAACTGGAGCCGCCTGTGGGGCTGTCTGAATATTACTGTTTTATTATATTTTCGGGCGGGCTGCTCCCCTTTTTCCCCA
CCTACCGTTTATTATCTTTT

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MNPFFKQKESETLELKKSTAQLKPAVISIVAILNKHQEGKLYFGVKDDGTVVGQEIGNDTLRTISQAISAYIEPKVYPVI
RQVTFEGKSCIEVEFQGNEVPYFAYGRAYIRTSDEDKPLSVKELENLILRKNKDQLKWDSSICREASLEDISEEKVRSFV
KEAGKEYKGLENSLKKLKLAKDGNLTNAAVILFGKKPEDFFPNAKLRCAVFATNDTSYIIDMQDYTGDLFYLIGEAEKYI
LKNIHIGMRLEGLKRIDVPEISKEAIREAIINAFCHRDYYEYDSVNVAVFKNRVEIRNKGLLYGGLTIEQIKTEMVSERR
NELIAEIFHEIHWIEKWGRGISLILSMEPDTDFKEVGTQFIVTFKRKYFEDSEERDGEKVGEKVGEKVGETLTQNQEVIL
SLIRENSRISARELSDRVGISARKTEENISKLKKKGLLKRIGSARGGYWEIIEK

Sequences:

>Translated_454_residues
MNPFFKQKESETLELKKSTAQLKPAVISIVAILNKHQEGKLYFGVKDDGTVVGQEIGNDTLRTISQAISAYIEPKVYPVI
RQVTFEGKSCIEVEFQGNEVPYFAYGRAYIRTSDEDKPLSVKELENLILRKNKDQLKWDSSICREASLEDISEEKVRSFV
KEAGKEYKGLENSLKKLKLAKDGNLTNAAVILFGKKPEDFFPNAKLRCAVFATNDTSYIIDMQDYTGDLFYLIGEAEKYI
LKNIHIGMRLEGLKRIDVPEISKEAIREAIINAFCHRDYYEYDSVNVAVFKNRVEIRNKGLLYGGLTIEQIKTEMVSERR
NELIAEIFHEIHWIEKWGRGISLILSMEPDTDFKEVGTQFIVTFKRKYFEDSEERDGEKVGEKVGEKVGETLTQNQEVIL
SLIRENSRISARELSDRVGISARKTEENISKLKKKGLLKRIGSARGGYWEIIEK
>Mature_454_residues
MNPFFKQKESETLELKKSTAQLKPAVISIVAILNKHQEGKLYFGVKDDGTVVGQEIGNDTLRTISQAISAYIEPKVYPVI
RQVTFEGKSCIEVEFQGNEVPYFAYGRAYIRTSDEDKPLSVKELENLILRKNKDQLKWDSSICREASLEDISEEKVRSFV
KEAGKEYKGLENSLKKLKLAKDGNLTNAAVILFGKKPEDFFPNAKLRCAVFATNDTSYIIDMQDYTGDLFYLIGEAEKYI
LKNIHIGMRLEGLKRIDVPEISKEAIREAIINAFCHRDYYEYDSVNVAVFKNRVEIRNKGLLYGGLTIEQIKTEMVSERR
NELIAEIFHEIHWIEKWGRGISLILSMEPDTDFKEVGTQFIVTFKRKYFEDSEERDGEKVGEKVGEKVGETLTQNQEVIL
SLIRENSRISARELSDRVGISARKTEENISKLKKKGLLKRIGSARGGYWEIIEK

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52000; Mature: 52000

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFFKQKESETLELKKSTAQLKPAVISIVAILNKHQEGKLYFGVKDDGTVVGQEIGNDT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECHHHCCHH
LRTISQAISAYIEPKVYPVIRQVTFEGKSCIEVEFQGNEVPYFAYGRAYIRTSDEDKPLS
HHHHHHHHHHHHCCCHHHHHHHHEECCCEEEEEEECCCCCCEEEECEEEEEECCCCCCCC
VKELENLILRKNKDQLKWDSSICREASLEDISEEKVRSFVKEAGKEYKGLENSLKKLKLA
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
KDGNLTNAAVILFGKKPEDFFPNAKLRCAVFATNDTSYIIDMQDYTGDLFYLIGEAEKYI
CCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEEECHHHHHH
LKNIHIGMRLEGLKRIDVPEISKEAIREAIINAFCHRDYYEYDSVNVAVFKNRVEIRNKG
HHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHCCCC
LLYGGLTIEQIKTEMVSERRNELIAEIFHEIHWIEKWGRGISLILSMEPDTDFKEVGTQF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
IVTFKRKYFEDSEERDGEKVGEKVGEKVGETLTQNQEVILSLIRENSRISARELSDRVGI
HHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCC
SARKTEENISKLKKKGLLKRIGSARGGYWEIIEK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MNPFFKQKESETLELKKSTAQLKPAVISIVAILNKHQEGKLYFGVKDDGTVVGQEIGNDT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECHHHCCHH
LRTISQAISAYIEPKVYPVIRQVTFEGKSCIEVEFQGNEVPYFAYGRAYIRTSDEDKPLS
HHHHHHHHHHHHCCCHHHHHHHHEECCCEEEEEEECCCCCCEEEECEEEEEECCCCCCCC
VKELENLILRKNKDQLKWDSSICREASLEDISEEKVRSFVKEAGKEYKGLENSLKKLKLA
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
KDGNLTNAAVILFGKKPEDFFPNAKLRCAVFATNDTSYIIDMQDYTGDLFYLIGEAEKYI
CCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEEECHHHHHH
LKNIHIGMRLEGLKRIDVPEISKEAIREAIINAFCHRDYYEYDSVNVAVFKNRVEIRNKG
HHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHCCCC
LLYGGLTIEQIKTEMVSERRNELIAEIFHEIHWIEKWGRGISLILSMEPDTDFKEVGTQF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
IVTFKRKYFEDSEERDGEKVGEKVGEKVGETLTQNQEVILSLIRENSRISARELSDRVGI
HHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCC
SARKTEENISKLKKKGLLKRIGSARGGYWEIIEK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]