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The map label for this gene is ymdB [C]

Identifier: 21226279

GI number: 21226279

Start: 242044

End: 242607

Strand: Direct

Name: ymdB [C]

Synonym: MM_0177

Alternate gene names: 21226279

Gene position: 242044-242607 (Clockwise)

Preceding gene: 21226277

Following gene: 21226280

Centisome position: 5.91

GC content: 43.44

Gene sequence:

>564_bases
GTGAAAAATCAGAATACCAGAGTAGAAGAAGGAATCCGTATGGAGCTAAACATAGATAGAATAAGGATATTCGAAGGCGA
TATCGTGAAAATGAGAGTGGATGCCATTGTTAATGCTGCAAATAATACACTCCTGGGAGGCGGAGGAGTAGACGGAGCAA
TCCACAGAGCTGCAGGTCCTGCATTACTTGAGGAATGTAAAACTCTTAACGGCTGCCCTACAGGAGAAGCAAAAATTACA
TCAGGGTACCTTCTGCCTGCAAAATATATTATACATACAGTTGGCCCTGTGTGGCAGGGAGGAGAAAAAGGAGAGGACGA
GCTTCTGGCTTCCTGCTACAGGAAAAGCCTTGAACTTGCCAGGGATTACAAAATAAAAACAATTGCTTTTCCAGCCATAA
GTACGGGAGCCTATGGCTTTCCTTCCGAAAGGGCAGCAGGTATTGCAGTTTCTCAGGTGAAGGAGTTTCTTCAGAAAAAC
GAGATTCCTGAGACTGTTTATCTGGTCTGTTATAACAAAGACAGCTGCAAAAGCATCAAAAAAGCCTTGAGCAAAATCTT
GTGA

Upstream 100 bases:

>100_bases
AAATAAGTCAGAAAAATAAGCTTCAGAAAGTCCGCTACCAGAAAAAGACTCTAAACCAGAAGAAACTCTAAAATACGGGA
TAAATCTCCTGATAAACCAG

Downstream 100 bases:

>100_bases
GCCCGTGATAAGAGAATTCAGATGGAAATATCTTATACATATTTTTTAATAATTTAACTGTCTTCAAAGAGATTGCTCAA
ATGCGTGGTAAACAATGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKNQNTRVEEGIRMELNIDRIRIFEGDIVKMRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECKTLNGCPTGEAKIT
SGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAFPAISTGAYGFPSERAAGIAVSQVKEFLQKN
EIPETVYLVCYNKDSCKSIKKALSKIL

Sequences:

>Translated_187_residues
MKNQNTRVEEGIRMELNIDRIRIFEGDIVKMRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECKTLNGCPTGEAKIT
SGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAFPAISTGAYGFPSERAAGIAVSQVKEFLQKN
EIPETVYLVCYNKDSCKSIKKALSKIL
>Mature_187_residues
MKNQNTRVEEGIRMELNIDRIRIFEGDIVKMRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECKTLNGCPTGEAKIT
SGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAFPAISTGAYGFPSERAAGIAVSQVKEFLQKN
EIPETVYLVCYNKDSCKSIKKALSKIL

Specific function: Unknown

COG id: COG2110

COG function: function code R; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Macro domain

Homologues:

Organism=Homo sapiens, GI117968621, Length=169, Percent_Identity=54.4378698224852, Blast_Score=183, Evalue=7e-47,
Organism=Homo sapiens, GI13569840, Length=163, Percent_Identity=50.920245398773, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI207450721, Length=140, Percent_Identity=38.5714285714286, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI8923143, Length=140, Percent_Identity=38.5714285714286, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI154813199, Length=171, Percent_Identity=34.5029239766082, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI20336746, Length=163, Percent_Identity=32.5153374233129, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI93141018, Length=155, Percent_Identity=31.6129032258064, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI93141020, Length=155, Percent_Identity=31.6129032258064, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4758496, Length=155, Percent_Identity=31.6129032258064, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI226371718, Length=166, Percent_Identity=33.1325301204819, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI226371716, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI226371714, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI226371712, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI226371710, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI226371706, Length=166, Percent_Identity=33.1325301204819, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI165377137, Length=163, Percent_Identity=29.4478527607362, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787283, Length=170, Percent_Identity=52.9411764705882, Blast_Score=188, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17538214, Length=155, Percent_Identity=52.258064516129, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24586353, Length=143, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y177_METMA (Q8Q0F9)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632201.1
- ProteinModelPortal:   Q8Q0F9
- SMR:   Q8Q0F9
- GeneID:   1478519
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0177
- NMPDR:   fig|192952.1.peg.177
- HOGENOM:   HBG682503
- OMA:   ARHVIHT
- ProtClustDB:   CLSK281843
- BioCyc:   MMAZ192952:MM0177-MONOMER
- HAMAP:   MF_01205_A
- InterPro:   IPR002589
- InterPro:   IPR022942
- SMART:   SM00506

Pfam domain/function: PF01661 Macro

EC number: NA

Molecular weight: Translated: 20362; Mature: 20362

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS51154 MACRO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQNTRVEEGIRMELNIDRIRIFEGDIVKMRVDAIVNAANNTLLGGGGVDGAIHRAAGP
CCCCCCCCCCCCEEEEECCEEEEECCCEEEEEHHHHHHHCCCEEECCCCCCHHHHHHCCH
ALLEECKTLNGCPTGEAKITSGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELA
HHHHHHHHCCCCCCCCCEECCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RDYKIKTIAFPAISTGAYGFPSERAAGIAVSQVKEFLQKNEIPETVYLVCYNKDSCKSIK
HCCCEEEEEECCCCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHH
KALSKIL
HHHHHCC
>Mature Secondary Structure
MKNQNTRVEEGIRMELNIDRIRIFEGDIVKMRVDAIVNAANNTLLGGGGVDGAIHRAAGP
CCCCCCCCCCCCEEEEECCEEEEECCCEEEEEHHHHHHHCCCEEECCCCCCHHHHHHCCH
ALLEECKTLNGCPTGEAKITSGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELA
HHHHHHHHCCCCCCCCCEECCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RDYKIKTIAFPAISTGAYGFPSERAAGIAVSQVKEFLQKNEIPETVYLVCYNKDSCKSIK
HCCCEEEEEECCCCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHH
KALSKIL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824