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The map label for this gene is pdtaS [H]

Identifier: 21226271

GI number: 21226271

Start: 223959

End: 226247

Strand: Reverse

Name: pdtaS [H]

Synonym: MM_0169

Alternate gene names: 21226271

Gene position: 226247-223959 (Counterclockwise)

Preceding gene: 21226272

Following gene: 21226270

Centisome position: 5.52

GC content: 44.78

Gene sequence:

>2289_bases
ATGACACTAGTCCAGAATGTAAAATCTGGAGTTGCGCTTATTGATGAGACTGGCAGGTTCGCAGTGGTAAACCCATCATT
TATGCAGATTTTTGGCCTGGATAGCGAGCTCGACATTCTAAATATTAATAGTCAGGAATGGAGCAGATGGGAAGTCTATG
GAGAGGATGGTAAACTACTGCATGTCGATGACCATCCCGTTAGAAAGGCTGTGAGAACCGGTAAGCCCGTGAAAGACCAG
CTCGTAGCCGTGCGGAATCCCGAGGAAAACGAACTCACCTGGATGCTGATAAGCGCCGAACCGGTCATGAAAGAAAATGG
CCATATATACAGGATAATCTGCACTTACCATGACATTACCGAACGCAAACGGGCTGAAGAGGCGCTGCGGAAGAGTGAGG
AGCGTTTTCGTGCTCTTGTAACGGCCAGTTCAGAAGTGGTATATCGTGTGAGTCCTGATTGGAGCGAGATGCGCCAGCTC
TATGGTCGAGGTTTTCTTGCAGATACGGAAATCCCAAGCAGTTCATGGCTTCAGGAATATGTTCCTCCGGAAGATCAGCC
TCGTGTGACAGCCGTCGTCAATGAAGCTATAAGTACAAAGAGCACTTACCAGCTGGAACATCGGGTCCGGCTAGCAGACG
GCAGCCTTGGATGGATCTTCTCGCGTGCGGTTCCTATGCTGAATGCTAACGGCGAAATCGTTGAATGGTTTGGTGCCGCC
AGCGATATCACCGAGCGCAAACGGGCCGAAGAGGCACTTCGTGAAAGTGAGGAGCGTCTGCGTCTCCTGGGCGACAACTT
ACCGAACAGTGCAGTTTATCAGTATATCCATGAGCCCGACGGCAGTGTCCGGTTTCTGTACTTCAGCACAGGCATCGAAC
GGCTCAACGGCATCAATGTCCAGGATGTGCTGCGTGACCCCAGCACACTGTACAGGCAAGTTCCGCCGGAATATTTAGAA
CGGGTCTTTGAAGCAGAGGCGCTTAGTGCGAGAGAGTTGTCGGATTTTGATATGGAAGTACCTATGCGGCTGCCAGATGG
CCAGGAGAAGTGGATGCGACTTCACTCCCGTCCTCGCCGGCTTCACGACGGCCGAAAGATATGGGATGGCGTTCAAATAG
ATGTCACTAAGCAAAAGCAGGCAGAGGAAGATCTAAATAAAGTACATTATAATCTGGAAAAATTAGTTGAAGAACGTACA
TCAGAGCTTGAAAAGGCTTATATTTCATTGAAAGAGAGTGAAAAAGGCCTCGCTGAAGCTCAAAGAATGGCTCATATTGG
AAACTGGGAATGGGACATTGTAACTGGTAAAGCATATTGGTCTGAGGAAATGTATCGTATCTTCAGATGCGACTCTAGAG
AATCAGCACCGCCTTATAACGAATTTTTAAATTACGTACATCCGGAAGATCGAGACTATTTGGATAGCGTCCTTAAGAAA
GCTGTAAAAGGAAGAATTCACAGTATTGAATATAGAATCGTCTTGGCTAATGGGGAAGAGCGTGCAGTCCATATGCAATC
TGAGGTCATTTTTGATGGAAAAAACAACCCTATCCGGATCAAAGGAATAATTCAGGATATTACAGAGCGTAAAGAAACAG
AAGAAGCCCTGAAAAATATTGAGACTGCCCGTAAAAAGGAAATCCACCATCGGATTAAGAATAATTTGCAGGTAATTTCC
TCACTACTTGACCTTCAGGCTGATAAGTTCGATAATCCGACAGTTATTGAGGCTTTCAGAGAAAGCCAGAACCGGGTTAT
ATCTATGGCTCTCATCCACGAAGAACTTTATAAAGGGGAAAATACCGATACTCTTAACTTTTCAACTTACATAAAAGAGT
TAGCTGAAAATCTTTTCCAGACTTATAGCCTTAGTAGCAAAAACATCCATCTGAATATGGATCTGGAAGAAAATGCGTTA
TTTAATATGGATGTTGCTGTCCCGCTGGGAATAATTATCAATGAACTCGTTTCCAATTCCCTCAAACATGCATTTCCGGG
CAGAGACAGTGGAGAAGTCCGAATCGAACTCCGCAGAGAAAAAAATGGAAAGCACAAAAAGGAATGTAATAAGGTCACCA
GTTTTATTCTGGCTGTTTCAGACAATGGTATAGGCATTCCTGAAAATCTCAAAATTGAAGTTGCTGGTAGTCTTGGCATA
CAGCTGATAACCGCCCTTGTTCATCAGTTAGATGGGGAACTTGAACTTAATAGGAATAACGGAGCTGAATTTATTATTAA
GTTTTCAGTAAGAGAAAAAAGTAATCAGGCGTCACATCCAGCAGTATAA

Upstream 100 bases:

>100_bases
AAGAGAAGGAATGAACACAAAAGGAAAATTGAATGGAAGTTTACAAGGAAGAATGCAGATGAGAAAATGTCAAAGTATTA
TGTGAAATAATTAAATGGTC

Downstream 100 bases:

>100_bases
AAGAATAAGTTAGGCATATTGCTGCCTAAGAGAGGGAGCCAGAGGGGAATATGGACACAAAAATGAAGCAATTTCCGACA
AATATCTCTAATCCTGTGCT

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MTLVQNVKSGVALIDETGRFAVVNPSFMQIFGLDSELDILNINSQEWSRWEVYGEDGKLLHVDDHPVRKAVRTGKPVKDQ
LVAVRNPEENELTWMLISAEPVMKENGHIYRIICTYHDITERKRAEEALRKSEERFRALVTASSEVVYRVSPDWSEMRQL
YGRGFLADTEIPSSSWLQEYVPPEDQPRVTAVVNEAISTKSTYQLEHRVRLADGSLGWIFSRAVPMLNANGEIVEWFGAA
SDITERKRAEEALRESEERLRLLGDNLPNSAVYQYIHEPDGSVRFLYFSTGIERLNGINVQDVLRDPSTLYRQVPPEYLE
RVFEAEALSARELSDFDMEVPMRLPDGQEKWMRLHSRPRRLHDGRKIWDGVQIDVTKQKQAEEDLNKVHYNLEKLVEERT
SELEKAYISLKESEKGLAEAQRMAHIGNWEWDIVTGKAYWSEEMYRIFRCDSRESAPPYNEFLNYVHPEDRDYLDSVLKK
AVKGRIHSIEYRIVLANGEERAVHMQSEVIFDGKNNPIRIKGIIQDITERKETEEALKNIETARKKEIHHRIKNNLQVIS
SLLDLQADKFDNPTVIEAFRESQNRVISMALIHEELYKGENTDTLNFSTYIKELAENLFQTYSLSSKNIHLNMDLEENAL
FNMDVAVPLGIIINELVSNSLKHAFPGRDSGEVRIELRREKNGKHKKECNKVTSFILAVSDNGIGIPENLKIEVAGSLGI
QLITALVHQLDGELELNRNNGAEFIIKFSVREKSNQASHPAV

Sequences:

>Translated_762_residues
MTLVQNVKSGVALIDETGRFAVVNPSFMQIFGLDSELDILNINSQEWSRWEVYGEDGKLLHVDDHPVRKAVRTGKPVKDQ
LVAVRNPEENELTWMLISAEPVMKENGHIYRIICTYHDITERKRAEEALRKSEERFRALVTASSEVVYRVSPDWSEMRQL
YGRGFLADTEIPSSSWLQEYVPPEDQPRVTAVVNEAISTKSTYQLEHRVRLADGSLGWIFSRAVPMLNANGEIVEWFGAA
SDITERKRAEEALRESEERLRLLGDNLPNSAVYQYIHEPDGSVRFLYFSTGIERLNGINVQDVLRDPSTLYRQVPPEYLE
RVFEAEALSARELSDFDMEVPMRLPDGQEKWMRLHSRPRRLHDGRKIWDGVQIDVTKQKQAEEDLNKVHYNLEKLVEERT
SELEKAYISLKESEKGLAEAQRMAHIGNWEWDIVTGKAYWSEEMYRIFRCDSRESAPPYNEFLNYVHPEDRDYLDSVLKK
AVKGRIHSIEYRIVLANGEERAVHMQSEVIFDGKNNPIRIKGIIQDITERKETEEALKNIETARKKEIHHRIKNNLQVIS
SLLDLQADKFDNPTVIEAFRESQNRVISMALIHEELYKGENTDTLNFSTYIKELAENLFQTYSLSSKNIHLNMDLEENAL
FNMDVAVPLGIIINELVSNSLKHAFPGRDSGEVRIELRREKNGKHKKECNKVTSFILAVSDNGIGIPENLKIEVAGSLGI
QLITALVHQLDGELELNRNNGAEFIIKFSVREKSNQASHPAV
>Mature_761_residues
TLVQNVKSGVALIDETGRFAVVNPSFMQIFGLDSELDILNINSQEWSRWEVYGEDGKLLHVDDHPVRKAVRTGKPVKDQL
VAVRNPEENELTWMLISAEPVMKENGHIYRIICTYHDITERKRAEEALRKSEERFRALVTASSEVVYRVSPDWSEMRQLY
GRGFLADTEIPSSSWLQEYVPPEDQPRVTAVVNEAISTKSTYQLEHRVRLADGSLGWIFSRAVPMLNANGEIVEWFGAAS
DITERKRAEEALRESEERLRLLGDNLPNSAVYQYIHEPDGSVRFLYFSTGIERLNGINVQDVLRDPSTLYRQVPPEYLER
VFEAEALSARELSDFDMEVPMRLPDGQEKWMRLHSRPRRLHDGRKIWDGVQIDVTKQKQAEEDLNKVHYNLEKLVEERTS
ELEKAYISLKESEKGLAEAQRMAHIGNWEWDIVTGKAYWSEEMYRIFRCDSRESAPPYNEFLNYVHPEDRDYLDSVLKKA
VKGRIHSIEYRIVLANGEERAVHMQSEVIFDGKNNPIRIKGIIQDITERKETEEALKNIETARKKEIHHRIKNNLQVISS
LLDLQADKFDNPTVIEAFRESQNRVISMALIHEELYKGENTDTLNFSTYIKELAENLFQTYSLSSKNIHLNMDLEENALF
NMDVAVPLGIIINELVSNSLKHAFPGRDSGEVRIELRREKNGKHKKECNKVTSFILAVSDNGIGIPENLKIEVAGSLGIQ
LITALVHQLDGELELNRNNGAEFIIKFSVREKSNQASHPAV

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87624; Mature: 87493

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVQNVKSGVALIDETGRFAVVNPSFMQIFGLDSELDILNINSQEWSRWEVYGEDGKLL
CCHHHHHHCCEEEEECCCCEEEECCCHHEEECCCCCCEEEECCCCCCCEEEEECCCCCEE
HVDDHPVRKAVRTGKPVKDQLVAVRNPEENELTWMLISAEPVMKENGHIYRIICTYHDIT
EECCCHHHHHHHCCCCHHHCEEEECCCCCCCEEEEEEECCCHHCCCCCEEEEEEECHHHH
ERKRAEEALRKSEERFRALVTASSEVVYRVSPDWSEMRQLYGRGFLADTEIPSSSWLQEY
HHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHCCCCEECCCCCCHHHHHHH
VPPEDQPRVTAVVNEAISTKSTYQLEHRVRLADGSLGWIFSRAVPMLNANGEIVEWFGAA
CCCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCCH
SDITERKRAEEALRESEERLRLLGDNLPNSAVYQYIHEPDGSVRFLYFSTGIERLNGINV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHCCCCH
QDVLRDPSTLYRQVPPEYLERVFEAEALSARELSDFDMEVPMRLPDGQEKWMRLHSRPRR
HHHHCCHHHHHHCCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHH
LHDGRKIWDGVQIDVTKQKQAEEDLNKVHYNLEKLVEERTSELEKAYISLKESEKGLAEA
HCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRMAHIGNWEWDIVTGKAYWSEEMYRIFRCDSRESAPPYNEFLNYVHPEDRDYLDSVLKK
HHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHH
AVKGRIHSIEYRIVLANGEERAVHMQSEVIFDGKNNPIRIKGIIQDITERKETEEALKNI
HHCCCEEEEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHH
ETARKKEIHHRIKNNLQVISSLLDLQADKFDNPTVIEAFRESQNRVISMALIHEELYKGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHCCC
NTDTLNFSTYIKELAENLFQTYSLSSKNIHLNMDLEENALFNMDVAVPLGIIINELVSNS
CCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHH
LKHAFPGRDSGEVRIELRREKNGKHKKECNKVTSFILAVSDNGIGIPENLKIEVAGSLGI
HHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCHHH
QLITALVHQLDGELELNRNNGAEFIIKFSVREKSNQASHPAV
HHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TLVQNVKSGVALIDETGRFAVVNPSFMQIFGLDSELDILNINSQEWSRWEVYGEDGKLL
CHHHHHHCCEEEEECCCCEEEECCCHHEEECCCCCCEEEECCCCCCCEEEEECCCCCEE
HVDDHPVRKAVRTGKPVKDQLVAVRNPEENELTWMLISAEPVMKENGHIYRIICTYHDIT
EECCCHHHHHHHCCCCHHHCEEEECCCCCCCEEEEEEECCCHHCCCCCEEEEEEECHHHH
ERKRAEEALRKSEERFRALVTASSEVVYRVSPDWSEMRQLYGRGFLADTEIPSSSWLQEY
HHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHCCCCEECCCCCCHHHHHHH
VPPEDQPRVTAVVNEAISTKSTYQLEHRVRLADGSLGWIFSRAVPMLNANGEIVEWFGAA
CCCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCCH
SDITERKRAEEALRESEERLRLLGDNLPNSAVYQYIHEPDGSVRFLYFSTGIERLNGINV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHCCCCH
QDVLRDPSTLYRQVPPEYLERVFEAEALSARELSDFDMEVPMRLPDGQEKWMRLHSRPRR
HHHHCCHHHHHHCCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHH
LHDGRKIWDGVQIDVTKQKQAEEDLNKVHYNLEKLVEERTSELEKAYISLKESEKGLAEA
HCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRMAHIGNWEWDIVTGKAYWSEEMYRIFRCDSRESAPPYNEFLNYVHPEDRDYLDSVLKK
HHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHH
AVKGRIHSIEYRIVLANGEERAVHMQSEVIFDGKNNPIRIKGIIQDITERKETEEALKNI
HHCCCEEEEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHH
ETARKKEIHHRIKNNLQVISSLLDLQADKFDNPTVIEAFRESQNRVISMALIHEELYKGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHCCC
NTDTLNFSTYIKELAENLFQTYSLSSKNIHLNMDLEENALFNMDVAVPLGIIINELVSNS
CCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHH
LKHAFPGRDSGEVRIELRREKNGKHKKECNKVTSFILAVSDNGIGIPENLKIEVAGSLGI
HHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCHHH
QLITALVHQLDGELELNRNNGAEFIIKFSVREKSNQASHPAV
HHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]