Click here to switch to the map view.

The map label for this gene is tldD [C]

Identifier: 21226229

GI number: 21226229

Start: 157341

End: 158696

Strand: Reverse

Name: tldD [C]

Synonym: MM_0127

Alternate gene names: 21226229

Gene position: 158696-157341 (Counterclockwise)

Preceding gene: 21226230

Following gene: 21226228

Centisome position: 3.87

GC content: 46.9

Gene sequence:

>1356_bases
GTGCAGGAACTGATCATGAATAGTATTATGCAGGACATTAAATTTTATGACTGCAGGGTGATAGAAGGCAGTTCCACTTC
TATCGTCCTGGATAACGGAAAGATAGAAGAAATATCCCGAAACTTCACAAAGGGGGCCGGAATAAGGGCCCTCTGCGGAG
GTTCCTGGGGCTATACGGCTGTTGAAGGGGATATTAACCTTAAACGCGGGGTCGACACGGCCTCAAAACTTGCTTTTTCT
ATGAATGCGAGCACCCCCAAAGAAGATGTAGAACTTGCAGCCGTGGATTCTCCTGAAGTAAGGGATCTTCCTGAGGTAAG
GACTAACCCTAGAGATATTGCAATTGAAGAAAAAGTAAGCCTTTTGAAGAGTATTGAAGAACACGCAAAGCTTGAAGGTG
TTCACAGTACAAAGGTAATGTATCTCGAGTCTGAGTTTAAAGTTGATTACCGGAACTCCGAAGGTCTGGAATGTGAATAT
GAGCTTTTAAATGTCGGTTTTGCAGTCTCTGCCGTTGCTTCGGAAAACGGCGTTTATCAGGCAGGCAGGGAAAGCCGTTT
CGGGTACGGTTATGAGCTTTTTGAAAACGAAAATGTTCTCGAACTTGCCGGAAAAGCGGGAAAGACCGCGCTTGAACTCT
TAAAAGCTAAAACACCTAAAGGCGGGGAAATGCCTGTGGTGCTTGACCAGGAGCTGGCAGGCGTATTTGCCCATGAAGCC
GTGGGGCATGCTTCAGAAGCCGACCTTGTGCTTGAAGGTGATTCCATTCTTGAAAACAGGATAGGAGAACAGATCGCATC
TCCGCTTATTAACATTATTGACGACCCGACTCTGCATGAGTTTGGATATTATCCTTTTGATGCAGAAGGTTCGGAGTCAA
AAAGGACTGAGATAATAAAGGACGGAATTTTTAACTCTTATCTCCACTCCCGGGAAACAGCAGCCAAACTTGGAGGAACT
CCGGGAAACTGCAGGGCTCAGGGTTATTCCATGCCCGTTGTCAGGATGAGCAACACATTCATTGACAACGGAGATTCCAG
GTTTGAAGAGATGCTCGAGGAAGTAAAGGACGGCATGTACCTTATAGGGTCAAGAGGCGGACAGGTAAACACCGGAGAAG
GTATATTCCAGTTCAATGCCGAAAAAGGGTACCTTATAAAAAACGGAGAGCTTACCGGGCTCTTAAGGGACGTCTCTCTT
TCAGGAAAGACGCTTGAAATCCTTAACCATGTGACCCTAGTCGGCAACGACCTGAAAATGACTGCCGGACGATGCGGAAA
AGCCGGACAGCTTGTACCTGTGTCTGACGGGTCCCCACATATTGCCATTTCGAAAGCACTTGTAGGAGGTGCCTGA

Upstream 100 bases:

>100_bases
GAAAGAATACAATTATTGAAAAACTCAAAAATATTACAAAACTAAGTTTCGACATCCCGGAAGTATCACCCGCTTCCGTA
CAGGCTATTAATCTCTTCGG

Downstream 100 bases:

>100_bases
AGATGTACGAGCTTGCAGAAAAAGCCCTGAAAATGGCAGAACAGGCAGGAGCCGAAGAAGCCGAAATTTATTACGCTGCA
AACCATTCTACAAGCGTCAA

Product: Zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQELIMNSIMQDIKFYDCRVIEGSSTSIVLDNGKIEEISRNFTKGAGIRALCGGSWGYTAVEGDINLKRGVDTASKLAFS
MNASTPKEDVELAAVDSPEVRDLPEVRTNPRDIAIEEKVSLLKSIEEHAKLEGVHSTKVMYLESEFKVDYRNSEGLECEY
ELLNVGFAVSAVASENGVYQAGRESRFGYGYELFENENVLELAGKAGKTALELLKAKTPKGGEMPVVLDQELAGVFAHEA
VGHASEADLVLEGDSILENRIGEQIASPLINIIDDPTLHEFGYYPFDAEGSESKRTEIIKDGIFNSYLHSRETAAKLGGT
PGNCRAQGYSMPVVRMSNTFIDNGDSRFEEMLEEVKDGMYLIGSRGGQVNTGEGIFQFNAEKGYLIKNGELTGLLRDVSL
SGKTLEILNHVTLVGNDLKMTAGRCGKAGQLVPVSDGSPHIAISKALVGGA

Sequences:

>Translated_451_residues
MQELIMNSIMQDIKFYDCRVIEGSSTSIVLDNGKIEEISRNFTKGAGIRALCGGSWGYTAVEGDINLKRGVDTASKLAFS
MNASTPKEDVELAAVDSPEVRDLPEVRTNPRDIAIEEKVSLLKSIEEHAKLEGVHSTKVMYLESEFKVDYRNSEGLECEY
ELLNVGFAVSAVASENGVYQAGRESRFGYGYELFENENVLELAGKAGKTALELLKAKTPKGGEMPVVLDQELAGVFAHEA
VGHASEADLVLEGDSILENRIGEQIASPLINIIDDPTLHEFGYYPFDAEGSESKRTEIIKDGIFNSYLHSRETAAKLGGT
PGNCRAQGYSMPVVRMSNTFIDNGDSRFEEMLEEVKDGMYLIGSRGGQVNTGEGIFQFNAEKGYLIKNGELTGLLRDVSL
SGKTLEILNHVTLVGNDLKMTAGRCGKAGQLVPVSDGSPHIAISKALVGGA
>Mature_451_residues
MQELIMNSIMQDIKFYDCRVIEGSSTSIVLDNGKIEEISRNFTKGAGIRALCGGSWGYTAVEGDINLKRGVDTASKLAFS
MNASTPKEDVELAAVDSPEVRDLPEVRTNPRDIAIEEKVSLLKSIEEHAKLEGVHSTKVMYLESEFKVDYRNSEGLECEY
ELLNVGFAVSAVASENGVYQAGRESRFGYGYELFENENVLELAGKAGKTALELLKAKTPKGGEMPVVLDQELAGVFAHEA
VGHASEADLVLEGDSILENRIGEQIASPLINIIDDPTLHEFGYYPFDAEGSESKRTEIIKDGIFNSYLHSRETAAKLGGT
PGNCRAQGYSMPVVRMSNTFIDNGDSRFEEMLEEVKDGMYLIGSRGGQVNTGEGIFQFNAEKGYLIKNGELTGLLRDVSL
SGKTLEILNHVTLVGNDLKMTAGRCGKAGQLVPVSDGSPHIAISKALVGGA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=30.6666666666667, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1790682, Length=352, Percent_Identity=25.8522727272727, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48882; Mature: 48882

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELIMNSIMQDIKFYDCRVIEGSSTSIVLDNGKIEEISRNFTKGAGIRALCGGSWGYTA
CHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCEE
VEGDINLKRGVDTASKLAFSMNASTPKEDVELAAVDSPEVRDLPEVRTNPRDIAIEEKVS
EECCCCHHCCCCHHHHEEEEECCCCCHHCEEEEECCCCCCCCCHHHCCCCCCEEHHHHHH
LLKSIEEHAKLEGVHSTKVMYLESEFKVDYRNSEGLECEYELLNVGFAVSAVASENGVYQ
HHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCEEEEEEEECCEEEEEECCCCCCEE
AGRESRFGYGYELFENENVLELAGKAGKTALELLKAKTPKGGEMPVVLDQELAGVFAHEA
CCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHH
VGHASEADLVLEGDSILENRIGEQIASPLINIIDDPTLHEFGYYPFDAEGSESKRTEIIK
HCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHH
DGIFNSYLHSRETAAKLGGTPGNCRAQGYSMPVVRMSNTFIDNGDSRFEEMLEEVKDGMY
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHCCEE
LIGSRGGQVNTGEGIFQFNAEKGYLIKNGELTGLLRDVSLSGKTLEILNHVTLVGNDLKM
EEECCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEECCCCCCHHHHHHHEEEECCCEEE
TAGRCGKAGQLVPVSDGSPHIAISKALVGGA
CCCCCCCCCCEEECCCCCCCEEEECHHCCCC
>Mature Secondary Structure
MQELIMNSIMQDIKFYDCRVIEGSSTSIVLDNGKIEEISRNFTKGAGIRALCGGSWGYTA
CHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCEE
VEGDINLKRGVDTASKLAFSMNASTPKEDVELAAVDSPEVRDLPEVRTNPRDIAIEEKVS
EECCCCHHCCCCHHHHEEEEECCCCCHHCEEEEECCCCCCCCCHHHCCCCCCEEHHHHHH
LLKSIEEHAKLEGVHSTKVMYLESEFKVDYRNSEGLECEYELLNVGFAVSAVASENGVYQ
HHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCEEEEEEEECCEEEEEECCCCCCEE
AGRESRFGYGYELFENENVLELAGKAGKTALELLKAKTPKGGEMPVVLDQELAGVFAHEA
CCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHH
VGHASEADLVLEGDSILENRIGEQIASPLINIIDDPTLHEFGYYPFDAEGSESKRTEIIK
HCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHH
DGIFNSYLHSRETAAKLGGTPGNCRAQGYSMPVVRMSNTFIDNGDSRFEEMLEEVKDGMY
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEECCCHHHHHHHHHHHHCCEE
LIGSRGGQVNTGEGIFQFNAEKGYLIKNGELTGLLRDVSLSGKTLEILNHVTLVGNDLKM
EEECCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEECCCCCCHHHHHHHEEEECCCEEE
TAGRCGKAGQLVPVSDGSPHIAISKALVGGA
CCCCCCCCCCEEECCCCCCCEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]