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The map label for this gene is 21226205

Identifier: 21226205

GI number: 21226205

Start: 130954

End: 132141

Strand: Reverse

Name: 21226205

Synonym: MM_0103

Alternate gene names: NA

Gene position: 132141-130954 (Counterclockwise)

Preceding gene: 21226206

Following gene: 21226203

Centisome position: 3.23

GC content: 47.22

Gene sequence:

>1188_bases
ATGGATTTTGAAGTAATTGATGACTTTGTGTACGAAGTAATTGGAATAATCGGGTCTGACCAGAACAACCTGTCCTGTGC
AGCCGATTTTGCTCTGGAAAATTCGAAAGAAAAATCGTTCTCCCCCGAACTCCTGCTCAACCTGTCCAGTGCTTGCAGGA
AGCAAAAAATGCATATGGAAGAATATGTGTTTGCAAAGGTCTGTTTGACGCAGGCTTCCGGAAAGCTCCGCGAAGATTCC
TGTTATGCGCTGGGTACTGCGGCACATCTGCTTGGCTTTTCCCCTGAAGCCGAAGCAAGCTACCTTGAAGTCCTGAAAGA
AAACCCCGGGAATGCGGATGCGCGATGTGCTTATGCTGAACTTCTTTTAGAGCTTGGAAGGATTGAAGATGCAGAAAATG
AGTATAAAACCGTACTTGAAAACTCACCCGAACATGTAAAGGCAAATGCAGGGTACGCTTACCTCCTTACCGAGTACGGG
TATTTCAGGGAAGCAGAAGACCGTTACCTGATAGCTCTTGCCGGCAATCCCGATTATGTTCCTGCCAGAGGTGGGTATGC
AAATATGCTTTTTGAGCTTGGAAGACTCAGGGATGCTGAAAAAGAGTACAGGCTTGCAATGAAGCTTGACCCTGAAGACC
CGAGCCTCCACCACAATTTCGGAGTTCTTCTCTCCTTCCTCGAGCGTTATTCAGAAGCCGAAGAAGAATACAGAAAAGCT
CTTTCCCTTAACCCCAGGCACAGGAGGACTCTTTTCAACTACGGAAACCTTCTTGCAAGGGAAGGCAGAGTCTCGGAAGC
TGAAAAACAGTACCTGGAAGCCCTTGCCCTTGACCAGAATGATGCAAAAGTGCATTCCAATTATGCAAACCTCCTTGCCC
GTTTCGGCAGGAGATATGAGGCTGAAATCGAATATAAAAAAGCTCTCAGCCTTGACCCGGAAAGTGCCGAGGGGCATTAC
AGCTATGGAAACCTCCTTTCGGAACTCGGGCGCTTCTCCGAAGCAGAGGAAGAATATAAGAAAGCCCTTAACCTGAACCC
CTATTATCCTCCTCTCCACTACAGCTACGGGCTGCTTATGAGAAAAATGAGGCGTTTCGACGAGGCTAAAATACAGTACA
TGAAAGCCATGCAGCTTGACCCGGATATCGGGAGCAAAATGACAGAAACCTGGATTATTCTGGATTAA

Upstream 100 bases:

>100_bases
ATTCACTCACTAATATATTCAACTAAATGTAAAACTATACTCTGGATGTTACACTGACAATCCCCCATTAAAAACACTAC
CCTTCTGAGGTGCCGGATGT

Downstream 100 bases:

>100_bases
TAACAAATGCGGAAACCGGAATTATTCTTGATTAACAAAAAATACCGAAACTGGATTATTCCGGATTAATAATACCGAAA
ATAGGGTCAGTCAGAAAAGG

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MDFEVIDDFVYEVIGIIGSDQNNLSCAADFALENSKEKSFSPELLLNLSSACRKQKMHMEEYVFAKVCLTQASGKLREDS
CYALGTAAHLLGFSPEAEASYLEVLKENPGNADARCAYAELLLELGRIEDAENEYKTVLENSPEHVKANAGYAYLLTEYG
YFREAEDRYLIALAGNPDYVPARGGYANMLFELGRLRDAEKEYRLAMKLDPEDPSLHHNFGVLLSFLERYSEAEEEYRKA
LSLNPRHRRTLFNYGNLLAREGRVSEAEKQYLEALALDQNDAKVHSNYANLLARFGRRYEAEIEYKKALSLDPESAEGHY
SYGNLLSELGRFSEAEEEYKKALNLNPYYPPLHYSYGLLMRKMRRFDEAKIQYMKAMQLDPDIGSKMTETWIILD

Sequences:

>Translated_395_residues
MDFEVIDDFVYEVIGIIGSDQNNLSCAADFALENSKEKSFSPELLLNLSSACRKQKMHMEEYVFAKVCLTQASGKLREDS
CYALGTAAHLLGFSPEAEASYLEVLKENPGNADARCAYAELLLELGRIEDAENEYKTVLENSPEHVKANAGYAYLLTEYG
YFREAEDRYLIALAGNPDYVPARGGYANMLFELGRLRDAEKEYRLAMKLDPEDPSLHHNFGVLLSFLERYSEAEEEYRKA
LSLNPRHRRTLFNYGNLLAREGRVSEAEKQYLEALALDQNDAKVHSNYANLLARFGRRYEAEIEYKKALSLDPESAEGHY
SYGNLLSELGRFSEAEEEYKKALNLNPYYPPLHYSYGLLMRKMRRFDEAKIQYMKAMQLDPDIGSKMTETWIILD
>Mature_395_residues
MDFEVIDDFVYEVIGIIGSDQNNLSCAADFALENSKEKSFSPELLLNLSSACRKQKMHMEEYVFAKVCLTQASGKLREDS
CYALGTAAHLLGFSPEAEASYLEVLKENPGNADARCAYAELLLELGRIEDAENEYKTVLENSPEHVKANAGYAYLLTEYG
YFREAEDRYLIALAGNPDYVPARGGYANMLFELGRLRDAEKEYRLAMKLDPEDPSLHHNFGVLLSFLERYSEAEEEYRKA
LSLNPRHRRTLFNYGNLLAREGRVSEAEKQYLEALALDQNDAKVHSNYANLLARFGRRYEAEIEYKKALSLDPESAEGHY
SYGNLLSELGRFSEAEEEYKKALNLNPYYPPLHYSYGLLMRKMRRFDEAKIQYMKAMQLDPDIGSKMTETWIILD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=299, Percent_Identity=29.4314381270903, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI32307148, Length=299, Percent_Identity=29.4314381270903, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI118766330, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI118766328, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301336134, Length=194, Percent_Identity=33.5051546391753, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI83415184, Length=194, Percent_Identity=33.5051546391753, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310123097, Length=330, Percent_Identity=26.0606060606061, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI310131789, Length=330, Percent_Identity=26.0606060606061, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI310110582, Length=330, Percent_Identity=26.0606060606061, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI22749211, Length=349, Percent_Identity=26.0744985673352, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI224809432, Length=284, Percent_Identity=26.056338028169, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI170784867, Length=322, Percent_Identity=24.8447204968944, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=299, Percent_Identity=28.4280936454849, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115532690, Length=299, Percent_Identity=28.4280936454849, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25147174, Length=246, Percent_Identity=27.2357723577236, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17647755, Length=299, Percent_Identity=30.4347826086957, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24585827, Length=299, Percent_Identity=30.4347826086957, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24585829, Length=299, Percent_Identity=30.4347826086957, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24647123, Length=302, Percent_Identity=27.1523178807947, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24581187, Length=196, Percent_Identity=34.6938775510204, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364285, Length=196, Percent_Identity=34.6938775510204, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920486, Length=195, Percent_Identity=31.7948717948718, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI161076610, Length=195, Percent_Identity=31.7948717948718, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 45207; Mature: 45207

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFEVIDDFVYEVIGIIGSDQNNLSCAADFALENSKEKSFSPELLLNLSSACRKQKMHME
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYVFAKVCLTQASGKLREDSCYALGTAAHLLGFSPEAEASYLEVLKENPGNADARCAYAE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
LLLELGRIEDAENEYKTVLENSPEHVKANAGYAYLLTEYGYFREAEDRYLIALAGNPDYV
HHHHHHCCCCCHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCC
PARGGYANMLFELGRLRDAEKEYRLAMKLDPEDPSLHHNFGVLLSFLERYSEAEEEYRKA
CCCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLNPRHRRTLFNYGNLLAREGRVSEAEKQYLEALALDQNDAKVHSNYANLLARFGRRYE
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
AEIEYKKALSLDPESAEGHYSYGNLLSELGRFSEAEEEYKKALNLNPYYPPLHYSYGLLM
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RKMRRFDEAKIQYMKAMQLDPDIGSKMTETWIILD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MDFEVIDDFVYEVIGIIGSDQNNLSCAADFALENSKEKSFSPELLLNLSSACRKQKMHME
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYVFAKVCLTQASGKLREDSCYALGTAAHLLGFSPEAEASYLEVLKENPGNADARCAYAE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
LLLELGRIEDAENEYKTVLENSPEHVKANAGYAYLLTEYGYFREAEDRYLIALAGNPDYV
HHHHHHCCCCCHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCC
PARGGYANMLFELGRLRDAEKEYRLAMKLDPEDPSLHHNFGVLLSFLERYSEAEEEYRKA
CCCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLNPRHRRTLFNYGNLLAREGRVSEAEKQYLEALALDQNDAKVHSNYANLLARFGRRYE
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
AEIEYKKALSLDPESAEGHYSYGNLLSELGRFSEAEEEYKKALNLNPYYPPLHYSYGLLM
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RKMRRFDEAKIQYMKAMQLDPDIGSKMTETWIILD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]