BacMap

Definition	Methanosarcina mazei Go1 chromosome, complete genome.
Accession	NC_003901
Length	4,096,345

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The map label for this gene is dppD [H]

Identifier: 21226108

GI number: 21226108

Start: 6523

End: 7500

Strand: Direct

Name: dppD [H]

Synonym: MM_0006

Alternate gene names: 21226108

Gene position: 6523-7500 (Clockwise)

Preceding gene: 21226107

Following gene: 21226109

Centisome position: 0.16

GC content: 41.62

Gene sequence:

>978_bases
ATGAAAAATAAAGCTAAGAATAATGCTGAAGAAAGCAGGAAAACTGAAGCCCTGTTAAAAGTAAAAGATCTCTCACTCTC
CTTTATCCAGTACACCTCAGGGCTCAGACAGACCGAGCTAAAAGTAATTTCCAATTTAAGTATAGAGGCTTATAGAGGAA
AAATACTGGCTGTTGTGGGATCAAGCGGTTCCGGGAAAAGCCTTCTTGCCCATGCTATTTTAGGAATTTTGCCTCCTAAC
GCGATACTTAATGGAAAAATTGAATACAATGGCATGCAGCTTACTCAGGAAAAGAAAGAAGAAATCAGGGGTAAAGAAAT
AGCCCTGGTTCCCCAATCCGTAACTTATCTGGACCCTTTAATGAGGGTTTCAGATCAGGTAATAGGGTGTGTGGAGGAAG
AAAAAGCAGGATTGATGAAGAAGCTCCAGAGGGAAATCTTTCAGAGATACGGCTTAAAACCGGATGTTGAAAGAATGTTT
CCTCATGAACTCTCAGGCGGGATGACCAGAAGAGTCCTGGTTTCCACTGCAGTAATAGGCTCTGCAAAGCTTGTAATTGC
AGACGAACCCACCCCTGGATTGGATGAAAAGACTCTGAATGAGACGCTGTATTACTTAAAAGACATGGCAAATAAAGGCT
GTGCAGTAATAGTTATAACTCATGATATAGAGGCAGCGCTAAAGATTTCCGATAAAATTGCCGTCTTTTATGCAGGCACA
GTCCTGGAAGTAGCCAATGCTGCAGATTTCAAAAACGATGGTGAGAACTTAAGGCATCCTTATACCCGGGCACTCTGGAA
TGCACTTCCCCAGAATAAATTCCAGGCAATTGAAGGGCATCAGCCAATGCAGGATGAAGTTATTGACGGATGTATTTTTT
ACGACAGGTGCTCAAAAAAGAACGAACTCTGCTCTAAAGGCATTCCTCAATTTCAAAATGTCAATGGAGGAATTGTGAGG
TGCAATAATGTATCTTAA

Upstream 100 bases:

>100_bases
TGGCATTTGACATGATAGGAGACAATCTGGGAAAAATAATTGATCCGAAAACTGCTCATGAATGAGTTGTATGTGAAAAT
TTCAATCTAAAGGTGGGAAC

Downstream 100 bases:

>100_bases
ATGCGAGAATATAAGTTTCGGATACAAAAAAAACAGTCTGGTTTTAGATAATGTAAGTCTGTCTTTAAGAAGCGGTGAGG
TTCTGGGCCTTGTAGGAGAC

Product: peptide ABC transporter ATP-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKNKAKNNAEESRKTEALLKVKDLSLSFIQYTSGLRQTELKVISNLSIEAYRGKILAVVGSSGSGKSLLAHAILGILPPN
AILNGKIEYNGMQLTQEKKEEIRGKEIALVPQSVTYLDPLMRVSDQVIGCVEEEKAGLMKKLQREIFQRYGLKPDVERMF
PHELSGGMTRRVLVSTAVIGSAKLVIADEPTPGLDEKTLNETLYYLKDMANKGCAVIVITHDIEAALKISDKIAVFYAGT
VLEVANAADFKNDGENLRHPYTRALWNALPQNKFQAIEGHQPMQDEVIDGCIFYDRCSKKNELCSKGIPQFQNVNGGIVR
CNNVS

Sequences:

>Translated_325_residues
MKNKAKNNAEESRKTEALLKVKDLSLSFIQYTSGLRQTELKVISNLSIEAYRGKILAVVGSSGSGKSLLAHAILGILPPN
AILNGKIEYNGMQLTQEKKEEIRGKEIALVPQSVTYLDPLMRVSDQVIGCVEEEKAGLMKKLQREIFQRYGLKPDVERMF
PHELSGGMTRRVLVSTAVIGSAKLVIADEPTPGLDEKTLNETLYYLKDMANKGCAVIVITHDIEAALKISDKIAVFYAGT
VLEVANAADFKNDGENLRHPYTRALWNALPQNKFQAIEGHQPMQDEVIDGCIFYDRCSKKNELCSKGIPQFQNVNGGIVR
CNNVS
>Mature_325_residues
MKNKAKNNAEESRKTEALLKVKDLSLSFIQYTSGLRQTELKVISNLSIEAYRGKILAVVGSSGSGKSLLAHAILGILPPN
AILNGKIEYNGMQLTQEKKEEIRGKEIALVPQSVTYLDPLMRVSDQVIGCVEEEKAGLMKKLQREIFQRYGLKPDVERMF
PHELSGGMTRRVLVSTAVIGSAKLVIADEPTPGLDEKTLNETLYYLKDMANKGCAVIVITHDIEAALKISDKIAVFYAGT
VLEVANAADFKNDGENLRHPYTRALWNALPQNKFQAIEGHQPMQDEVIDGCIFYDRCSKKNELCSKGIPQFQNVNGGIVR
CNNVS

Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=204, Percent_Identity=28.4313725490196, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI11967969, Length=233, Percent_Identity=26.6094420600858, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI21536376, Length=216, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI150417984, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI116734710, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI27262624, Length=233, Percent_Identity=26.6094420600858, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI27262626, Length=233, Percent_Identity=26.6094420600858, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI45446740, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI47078218, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI48994883, Length=329, Percent_Identity=31.6109422492401, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789963, Length=318, Percent_Identity=31.7610062893082, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787759, Length=325, Percent_Identity=30.4615384615385, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787500, Length=339, Percent_Identity=29.7935103244838, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787548, Length=313, Percent_Identity=27.1565495207668, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789962, Length=337, Percent_Identity=29.080118694362, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788506, Length=268, Percent_Identity=30.9701492537313, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI145693107, Length=276, Percent_Identity=30.0724637681159, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787758, Length=299, Percent_Identity=25.4180602006689, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787105, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87081834, Length=209, Percent_Identity=29.6650717703349, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=29.9065420560748, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789890, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787547, Length=240, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48995001, Length=208, Percent_Identity=28.3653846153846, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=261, Percent_Identity=25.6704980842912, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789032, Length=234, Percent_Identity=28.6324786324786, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786872, Length=225, Percent_Identity=27.1111111111111, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786398, Length=254, Percent_Identity=26.3779527559055, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788225, Length=229, Percent_Identity=27.0742358078603, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786319, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790544, Length=264, Percent_Identity=23.8636363636364, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787089, Length=239, Percent_Identity=25.1046025104602, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788165, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786703, Length=207, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=28.1512605042017, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788761, Length=229, Percent_Identity=24.8908296943231, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789991, Length=211, Percent_Identity=24.1706161137441, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786563, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788450, Length=211, Percent_Identity=25.1184834123223, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789672, Length=218, Percent_Identity=23.8532110091743, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788210, Length=204, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789873, Length=188, Percent_Identity=28.1914893617021, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788472, Length=207, Percent_Identity=24.1545893719807, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789891, Length=228, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790190, Length=261, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788897, Length=207, Percent_Identity=22.7053140096618, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787712, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789586, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790525, Length=244, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787792, Length=271, Percent_Identity=21.7712177121771, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=259, Percent_Identity=23.9382239382239, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87081709, Length=233, Percent_Identity=24.4635193133047, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=252, Percent_Identity=28.1746031746032, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565586, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=208, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=208, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=208, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=237, Percent_Identity=27.8481012658228, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=232, Percent_Identity=25.8620689655172, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=197, Percent_Identity=25.8883248730964, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24666092, Length=209, Percent_Identity=27.7511961722488, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643674, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007184, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221500365, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512771, Length=215, Percent_Identity=26.9767441860465, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007328, Length=212, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28574150, Length=212, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136592, Length=236, Percent_Identity=29.6610169491525, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 35955; Mature: 35955

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKAKNNAEESRKTEALLKVKDLSLSFIQYTSGLRQTELKVISNLSIEAYRGKILAVVG
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCEEEECCEEEEEEE
SSGSGKSLLAHAILGILPPNAILNGKIEYNGMQLTQEKKEEIRGKEIALVPQSVTYLDPL
CCCCCHHHHHHHHHHHCCCCCEEECEEEECCCCCCHHHHHHHCCCEEEEECCHHHHHHHH
MRVSDQVIGCVEEEKAGLMKKLQREIFQRYGLKPDVERMFPHELSGGMTRRVLVSTAVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHC
SAKLVIADEPTPGLDEKTLNETLYYLKDMANKGCAVIVITHDIEAALKISDKIAVFYAGT
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHEECCEEEEEECCH
VLEVANAADFKNDGENLRHPYTRALWNALPQNKFQAIEGHQPMQDEVIDGCIFYDRCSKK
HHHHHHHHCCCCCCCHHCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCH
NELCSKGIPQFQNVNGGIVRCNNVS
HHHHHCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure
MKNKAKNNAEESRKTEALLKVKDLSLSFIQYTSGLRQTELKVISNLSIEAYRGKILAVVG
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCEEEECCEEEEEEE
SSGSGKSLLAHAILGILPPNAILNGKIEYNGMQLTQEKKEEIRGKEIALVPQSVTYLDPL
CCCCCHHHHHHHHHHHCCCCCEEECEEEECCCCCCHHHHHHHCCCEEEEECCHHHHHHHH
MRVSDQVIGCVEEEKAGLMKKLQREIFQRYGLKPDVERMFPHELSGGMTRRVLVSTAVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHC
SAKLVIADEPTPGLDEKTLNETLYYLKDMANKGCAVIVITHDIEAALKISDKIAVFYAGT
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHEECCEEEEEECCH
VLEVANAADFKNDGENLRHPYTRALWNALPQNKFQAIEGHQPMQDEVIDGCIFYDRCSKK
HHHHHHHHCCCCCCCHHCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCH
NELCSKGIPQFQNVNGGIVRCNNVS
HHHHHCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]