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The map label for this gene is exuT [H]

Identifier: 212224537

GI number: 212224537

Start: 1260482

End: 1261609

Strand: Reverse

Name: exuT [H]

Synonym: TON_1386

Alternate gene names: 212224537

Gene position: 1261609-1260482 (Counterclockwise)

Preceding gene: 212224541

Following gene: 212224535

Centisome position: 68.28

GC content: 49.2

Gene sequence:

>1128_bases
ATGCGCCGCAGGCTTTTACTCCTTGTATCCCTTGGCTGGATTTTCAACTACGCCCACAGGATGGCGATTCCACCCCTGAT
TCCGATGATAAAGGCAGAACTCGGAATAAACAACGCTGAGGCTGGGCTTCTGATGACCTCCCTGCTCCTTCCTTACGCTC
TCATTCAGGTTCCTGCGGGCTATTTCGGCGATAGAATCGGGCGAAAAAGACTCCTCGTGCTCAGTATAATAGGTTACTCA
CTTTCATCCGCTCTGATAATCTTTGCACGGGAGTACTGGGAGCTTCTTGCAGTTAGGGCCATCTACGGTCTATTTTCTGG
TCTCTACTATGCCCCTGCAACTGCTCTAATAAGCGAGGTCTACCGTGAGAGAAAGGGCTCTGCCCTGGGCGTCTTCATGA
TAGGTCCGCCGGTTGGAAGTGGAATAGCACCCATTATAGTCGTGCCCATAGCTCTCGACCTTGAGTGGCGCTATGCTTTC
TTGGTTCTCTCTGTTATGAGCCTCCTCGTTGGCCTTGCGCTGGCCTTTGTGGTAAGGGGAGAAGTTTCAAAGCCAAGCAG
AGTGAGCTTTTCAATCCCCAAAAATGTTTTCCTCTTGAGTGCTGCCAACTTCATAGTTCTAGCTGCCTTTTTCGGCCTTC
TCACATTCCTCGTTTCATTTCTTGTAAATTCCGGCGTTTCCATTGAGATGGCCTCCCTGCTTTTTTCGCTCCTATCTGTC
ATAGGCATAGCGGGTTCTCTCTTTGGGGGAGGACTTTACGATAGAATCGGAAGGAAGAGCATCACGGTTGTATTTGGACT
CAACGCCTTGTTGACCTTTGTTTTAACAGTTACGGCATCGCCCTTGGTCATCGTACCTCTTGGTCTCACCTTTTACTCCG
TGGGAGCCATAGTCACAGCTTATACTTCGGAGAAGGCCAGTGGGGAAAACCTCGGCTCAGTCATGGGCTTCGTTAATATG
GTTGGATTCTTCGGGGCAACGATAGGCCCTTACTTCCTTGGCCTTCTGATAGATGGCTTTGGCTACAAGATGGCTTTCTT
ATCAATTCCTGTGATGTATCTCCTCGCCTGGGCAATAATCAAAGTTGAAGAAAAGCTGGAAGAAAAGGAAGATCTCAGCC
GTACATGA

Upstream 100 bases:

>100_bases
AACTCTTTCTTCGTCATAGCTGCCCATAAATTACTATCTATAATTGTTCTTAAGCCTTTGGACAGACAATTTTTTAAGCG
CTTAACTTTTTATCGAAAAC

Downstream 100 bases:

>100_bases
CCTCGTGCATGGCTATCTGCTGGGAGAGCCTCTGCTCCGAGCCAAGAACTTTCTCAATAGCTTTGAGGAAGTCTTCCTGT
GTCACGTACTCACGTCTGTC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRRRLLLLVSLGWIFNYAHRMAIPPLIPMIKAELGINNAEAGLLMTSLLLPYALIQVPAGYFGDRIGRKRLLVLSIIGYS
LSSALIIFAREYWELLAVRAIYGLFSGLYYAPATALISEVYRERKGSALGVFMIGPPVGSGIAPIIVVPIALDLEWRYAF
LVLSVMSLLVGLALAFVVRGEVSKPSRVSFSIPKNVFLLSAANFIVLAAFFGLLTFLVSFLVNSGVSIEMASLLFSLLSV
IGIAGSLFGGGLYDRIGRKSITVVFGLNALLTFVLTVTASPLVIVPLGLTFYSVGAIVTAYTSEKASGENLGSVMGFVNM
VGFFGATIGPYFLGLLIDGFGYKMAFLSIPVMYLLAWAIIKVEEKLEEKEDLSRT

Sequences:

>Translated_375_residues
MRRRLLLLVSLGWIFNYAHRMAIPPLIPMIKAELGINNAEAGLLMTSLLLPYALIQVPAGYFGDRIGRKRLLVLSIIGYS
LSSALIIFAREYWELLAVRAIYGLFSGLYYAPATALISEVYRERKGSALGVFMIGPPVGSGIAPIIVVPIALDLEWRYAF
LVLSVMSLLVGLALAFVVRGEVSKPSRVSFSIPKNVFLLSAANFIVLAAFFGLLTFLVSFLVNSGVSIEMASLLFSLLSV
IGIAGSLFGGGLYDRIGRKSITVVFGLNALLTFVLTVTASPLVIVPLGLTFYSVGAIVTAYTSEKASGENLGSVMGFVNM
VGFFGATIGPYFLGLLIDGFGYKMAFLSIPVMYLLAWAIIKVEEKLEEKEDLSRT
>Mature_375_residues
MRRRLLLLVSLGWIFNYAHRMAIPPLIPMIKAELGINNAEAGLLMTSLLLPYALIQVPAGYFGDRIGRKRLLVLSIIGYS
LSSALIIFAREYWELLAVRAIYGLFSGLYYAPATALISEVYRERKGSALGVFMIGPPVGSGIAPIIVVPIALDLEWRYAF
LVLSVMSLLVGLALAFVVRGEVSKPSRVSFSIPKNVFLLSAANFIVLAAFFGLLTFLVSFLVNSGVSIEMASLLFSLLSV
IGIAGSLFGGGLYDRIGRKSITVVFGLNALLTFVLTVTASPLVIVPLGLTFYSVGAIVTAYTSEKASGENLGSVMGFVNM
VGFFGATIGPYFLGLLIDGFGYKMAFLSIPVMYLLAWAIIKVEEKLEEKEDLSRT

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=311, Percent_Identity=27.6527331189711, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082320, Length=196, Percent_Identity=27.0408163265306, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082310, Length=394, Percent_Identity=20.5583756345178, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082404, Length=318, Percent_Identity=27.9874213836478, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17539092, Length=180, Percent_Identity=25.5555555555556, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17864456, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654041, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654039, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654037, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654044, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40584; Mature: 40584

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRLLLLVSLGWIFNYAHRMAIPPLIPMIKAELGINNAEAGLLMTSLLLPYALIQVPAG
CCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
YFGDRIGRKRLLVLSIIGYSLSSALIIFAREYWELLAVRAIYGLFSGLYYAPATALISEV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRERKGSALGVFMIGPPVGSGIAPIIVVPIALDLEWRYAFLVLSVMSLLVGLALAFVVRG
HHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHC
EVSKPSRVSFSIPKNVFLLSAANFIVLAAFFGLLTFLVSFLVNSGVSIEMASLLFSLLSV
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IGIAGSLFGGGLYDRIGRKSITVVFGLNALLTFVLTVTASPLVIVPLGLTFYSVGAIVTA
HHHHHHHHCCHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
YTSEKASGENLGSVMGFVNMVGFFGATIGPYFLGLLIDGFGYKMAFLSIPVMYLLAWAII
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KVEEKLEEKEDLSRT
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRRLLLLVSLGWIFNYAHRMAIPPLIPMIKAELGINNAEAGLLMTSLLLPYALIQVPAG
CCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
YFGDRIGRKRLLVLSIIGYSLSSALIIFAREYWELLAVRAIYGLFSGLYYAPATALISEV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRERKGSALGVFMIGPPVGSGIAPIIVVPIALDLEWRYAFLVLSVMSLLVGLALAFVVRG
HHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHC
EVSKPSRVSFSIPKNVFLLSAANFIVLAAFFGLLTFLVSFLVNSGVSIEMASLLFSLLSV
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IGIAGSLFGGGLYDRIGRKSITVVFGLNALLTFVLTVTASPLVIVPLGLTFYSVGAIVTA
HHHHHHHHCCHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
YTSEKASGENLGSVMGFVNMVGFFGATIGPYFLGLLIDGFGYKMAFLSIPVMYLLAWAII
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KVEEKLEEKEDLSRT
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]