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The map label for this gene is visC [H]

Identifier: 209695955

GI number: 209695955

Start: 2718141

End: 2719346

Strand: Reverse

Name: visC [H]

Synonym: VSAL_I2537

Alternate gene names: 209695955

Gene position: 2719346-2718141 (Counterclockwise)

Preceding gene: 209695956

Following gene: 209695952

Centisome position: 81.78

GC content: 40.05

Gene sequence:

>1206_bases
ATGATGCAAAGTGTAGATATTGCGATTATTGGGGGGGGCATGGTTGGCTTGACTGTTGCTGCTGCTCTAGAAAAAAGCGG
TTTAAGAATCGCAATTATAGAAAGTCACTTACCTGATGCGGAATTAACTGCTTTACCTGATGTTCGTGTTTCAGCGATTA
GTCGTGCAAGTGAAAATATTTTAACGAATGTTGGTGCTTGGGAAGGCATTATCTCAAGACGAGCGGCGGCTTATACTTCA
ATGAAAGTATGGGAACAAGACAGCTTTGCGCATATTGATTTTGATGCAACACAAATCGCCCAACAAGATTTAGGCCATAT
TATTGAGAACCGAGTTATTCAACTTTCTTTACTCGATAAAATAACGAAACAAGATAACGTAACGTTATTCGCTCCTGAGC
GTTGTGCGAGTATTATGTTTGGCGAAAGTGAAGCATGGATTAATTTAGAATCAGGCAAAGGAATAACGGCTAAGTTGGTT
GTTGGTGCTGATGGGGCTAATTCATGGTTACGTAATCAATTAGATATTCCTCTTACACATTGGGATTATGGACACAGTGC
ACTGGTAGCCAATGTTCGAACTGTTGATGATCACCATAAAGCAGCTCGTCAAATTTTTAGATCTGAAGGCCCACTTGCTT
TCCTTCCGTTAAGTGAGCCCAATCTAAGCTCTATTGTATGGTCACTTGATCCATTACATGCTGAAAATTTAGTATCAATG
CCTAGCGATGAGTTTAATAAGCAATTAACGGCGGCGTTTGATAATCAATTGGGGCTTTGCAAGGTTGAAGGAGAGCGACA
AGCTTTTCCATTAAAAATGCGCTATGCAAAAGACTTTGTCCGAGAGCGTGCTGTATTAGTCGGAGATGCCGCTCATACGA
TTCACCCACTCGCAGGGCAAGGTGTCAATTTAGGATTAGCAGATGCAGCGGCATTAGCTGAAACGATTATGACGTTGCAA
CAAGAGAACAAAGATATTGGTTTAAAAACCAATTTACGGAGTTTTGAGCGATGGAGAAAAACGGAAGCTGCTCAAATGAT
AGCGTCTATGCAAGGTTTTAAAGAGTTATTCTCAGGCTCTAATCCACTAAAAAAACTGGTTAGAGGTATTGGTATGTCAT
TAACGAATGAACTTACACCAGTAAAAGATGAATGTTTAAAAAGAGCATTAGGATTATCGGGGCATTTACCAAAAATAGCA
AAATAA

Upstream 100 bases:

>100_bases
TGGTAGTAGGAAGAAATATGAGCTTATACGCGGTTGATATTTTCCGTTCTTTTTTAAAACCCCTAACATTACGTGCAATG
GGTCGAGTGAATAGATAATT

Downstream 100 bases:

>100_bases
TCCCATTAAGTAGACAGTAAAAAGGTAGCTCATGGCTACCTTTTTTAGTGTTCAATTCTTGATTTTTTACGTTTAATGAT
TCTGTATTAATAGGCCATTC

Product: 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MMQSVDIAIIGGGMVGLTVAAALEKSGLRIAIIESHLPDAELTALPDVRVSAISRASENILTNVGAWEGIISRRAAAYTS
MKVWEQDSFAHIDFDATQIAQQDLGHIIENRVIQLSLLDKITKQDNVTLFAPERCASIMFGESEAWINLESGKGITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANVRTVDDHHKAARQIFRSEGPLAFLPLSEPNLSSIVWSLDPLHAENLVSM
PSDEFNKQLTAAFDNQLGLCKVEGERQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETIMTLQ
QENKDIGLKTNLRSFERWRKTEAAQMIASMQGFKELFSGSNPLKKLVRGIGMSLTNELTPVKDECLKRALGLSGHLPKIA
K

Sequences:

>Translated_401_residues
MMQSVDIAIIGGGMVGLTVAAALEKSGLRIAIIESHLPDAELTALPDVRVSAISRASENILTNVGAWEGIISRRAAAYTS
MKVWEQDSFAHIDFDATQIAQQDLGHIIENRVIQLSLLDKITKQDNVTLFAPERCASIMFGESEAWINLESGKGITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANVRTVDDHHKAARQIFRSEGPLAFLPLSEPNLSSIVWSLDPLHAENLVSM
PSDEFNKQLTAAFDNQLGLCKVEGERQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETIMTLQ
QENKDIGLKTNLRSFERWRKTEAAQMIASMQGFKELFSGSNPLKKLVRGIGMSLTNELTPVKDECLKRALGLSGHLPKIA
K
>Mature_401_residues
MMQSVDIAIIGGGMVGLTVAAALEKSGLRIAIIESHLPDAELTALPDVRVSAISRASENILTNVGAWEGIISRRAAAYTS
MKVWEQDSFAHIDFDATQIAQQDLGHIIENRVIQLSLLDKITKQDNVTLFAPERCASIMFGESEAWINLESGKGITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANVRTVDDHHKAARQIFRSEGPLAFLPLSEPNLSSIVWSLDPLHAENLVSM
PSDEFNKQLTAAFDNQLGLCKVEGERQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETIMTLQ
QENKDIGLKTNLRSFERWRKTEAAQMIASMQGFKELFSGSNPLKKLVRGIGMSLTNELTPVKDECLKRALGLSGHLPKIA
K

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=386, Percent_Identity=33.6787564766839, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI32967307, Length=351, Percent_Identity=33.048433048433, Blast_Score=162, Evalue=5e-40,
Organism=Escherichia coli, GI1789273, Length=393, Percent_Identity=54.4529262086514, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=35.2040816326531, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=30.5128205128205, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25146631, Length=430, Percent_Identity=32.093023255814, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321694, Length=449, Percent_Identity=26.7260579064588, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19920760, Length=421, Percent_Identity=30.166270783848, Blast_Score=167, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43818; Mature: 43818

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQSVDIAIIGGGMVGLTVAAALEKSGLRIAIIESHLPDAELTALPDVRVSAISRASENI
CCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHH
LTNVGAWEGIISRRAAAYTSMKVWEQDSFAHIDFDATQIAQQDLGHIIENRVIQLSLLDK
HHHCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHH
ITKQDNVTLFAPERCASIMFGESEAWINLESGKGITAKLVVGADGANSWLRNQLDIPLTH
HHCCCCEEEECHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHCCCCCCEEE
WDYGHSALVANVRTVDDHHKAARQIFRSEGPLAFLPLSEPNLSSIVWSLDPLHAENLVSM
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEECCCCCHHHHHCC
PSDEFNKQLTAAFDNQLGLCKVEGERQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQ
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCHHHHCCCCCC
GVNLGLADAAALAETIMTLQQENKDIGLKTNLRSFERWRKTEAAQMIASMQGFKELFSGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPLKKLVRGIGMSLTNELTPVKDECLKRALGLSGHLPKIAK
CHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMQSVDIAIIGGGMVGLTVAAALEKSGLRIAIIESHLPDAELTALPDVRVSAISRASENI
CCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHH
LTNVGAWEGIISRRAAAYTSMKVWEQDSFAHIDFDATQIAQQDLGHIIENRVIQLSLLDK
HHHCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHH
ITKQDNVTLFAPERCASIMFGESEAWINLESGKGITAKLVVGADGANSWLRNQLDIPLTH
HHCCCCEEEECHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHCCCCCCEEE
WDYGHSALVANVRTVDDHHKAARQIFRSEGPLAFLPLSEPNLSSIVWSLDPLHAENLVSM
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEECCCCCHHHHHCC
PSDEFNKQLTAAFDNQLGLCKVEGERQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQ
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCHHHHCCCCCC
GVNLGLADAAALAETIMTLQQENKDIGLKTNLRSFERWRKTEAAQMIASMQGFKELFSGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPLKKLVRGIGMSLTNELTPVKDECLKRALGLSGHLPKIAK
CHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]