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The map label for this gene is pdxY [H]

Identifier: 209695908

GI number: 209695908

Start: 2666559

End: 2667428

Strand: Reverse

Name: pdxY [H]

Synonym: VSAL_I2490

Alternate gene names: 209695908

Gene position: 2667428-2666559 (Counterclockwise)

Preceding gene: 209695909

Following gene: 209695907

Centisome position: 80.22

GC content: 41.03

Gene sequence:

>870_bases
ATGAAACGTATTCTTTCCATTCAGTCTCATGTGGTATTTGGTTGTGCAGGCAACAGTGCAGCGGTTTTTCCAATGCGAAG
AATGGGAATGGAAGTGTGGCCAATTAACACGGTACAGTTTTCAAATCACACACAATACTTACAAGGCTGGAAAGGCATTG
CTATGCCTGCGGGCCATATTTCAGAATTAGTTGATGGTCTATCAGCAATTGAAGCAACAAAAGTCTGTGATGCCGTATTA
AGTGGTTACTTAGGATCAGCAGCACAAGGCCAAGAAATTATTACGGCTGTTAAAAAAATCAAACAAGACAACTCAAACGC
GATTTACTTCTGCGATCCTGTGATGGGACATCCTGAGAAGGGGTGCATCGTTGCCCCAGAAGTGGAAGTGTTTTTTAAAG
AATCTGCGTTAGCATCAGCGGATATTATTGCGCCAAATTTACTTGAATTAGAAAGTTTATCTGGCATGACTATTAATACC
TTAGAGCAAGTGATTGAAGCAAATAATCAACTGCTTGAAAAAGGCGTTAAGATGGTAGTGGTAAAACACTTAAGTCGTGC
GGGAATTAAAAAAGATCGTTTTGAAATGCTATTAACCACCAAAGACGGCAGTTACCATATTTCTCGTCCTTTATATGACT
TTGATGCAAAGCGTCAGCCAGTAGGGGCTGGAGATTTAATCAGTGGCGTAATGCTGGCTAACTTAATTGCGGGTTGCTCT
CCAATTGATGCGTTTGAACGTACCAATGCAGCGGTTGATTCTGTGATGAAAGAAACCTTCAAACAAGGTGCGTATGAGCT
ACAGCTTATTGCCTCACAAGAACAATTTAATGCGCCAAATATTACGGTAAAAGCGACGAAAGTAGCGTAA

Upstream 100 bases:

>100_bases
GTGAAAGTATTAAAAGAAGATTAAGCCCTAGGGTTTTAAAGGATTATCGTTTATTTTAGGGCACGGAAGCCCTTACTCTA
TTTTAAATTATGGTGATGTT

Downstream 100 bases:

>100_bases
TCCGTTATATTCACAATGAATAGAAAATGCAAAGCCCTTTAATCCCTATCGTCAGTGATTAAAGGGCTTTTTTATTGTGT
TGATTTCTTTTTAATTATTG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKRILSIQSHVVFGCAGNSAAVFPMRRMGMEVWPINTVQFSNHTQYLQGWKGIAMPAGHISELVDGLSAIEATKVCDAVL
SGYLGSAAQGQEIITAVKKIKQDNSNAIYFCDPVMGHPEKGCIVAPEVEVFFKESALASADIIAPNLLELESLSGMTINT
LEQVIEANNQLLEKGVKMVVVKHLSRAGIKKDRFEMLLTTKDGSYHISRPLYDFDAKRQPVGAGDLISGVMLANLIAGCS
PIDAFERTNAAVDSVMKETFKQGAYELQLIASQEQFNAPNITVKATKVA

Sequences:

>Translated_289_residues
MKRILSIQSHVVFGCAGNSAAVFPMRRMGMEVWPINTVQFSNHTQYLQGWKGIAMPAGHISELVDGLSAIEATKVCDAVL
SGYLGSAAQGQEIITAVKKIKQDNSNAIYFCDPVMGHPEKGCIVAPEVEVFFKESALASADIIAPNLLELESLSGMTINT
LEQVIEANNQLLEKGVKMVVVKHLSRAGIKKDRFEMLLTTKDGSYHISRPLYDFDAKRQPVGAGDLISGVMLANLIAGCS
PIDAFERTNAAVDSVMKETFKQGAYELQLIASQEQFNAPNITVKATKVA
>Mature_289_residues
MKRILSIQSHVVFGCAGNSAAVFPMRRMGMEVWPINTVQFSNHTQYLQGWKGIAMPAGHISELVDGLSAIEATKVCDAVL
SGYLGSAAQGQEIITAVKKIKQDNSNAIYFCDPVMGHPEKGCIVAPEVEVFFKESALASADIIAPNLLELESLSGMTINT
LEQVIEANNQLLEKGVKMVVVKHLSRAGIKKDRFEMLLTTKDGSYHISRPLYDFDAKRQPVGAGDLISGVMLANLIAGCS
PIDAFERTNAAVDSVMKETFKQGAYELQLIASQEQFNAPNITVKATKVA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=315, Percent_Identity=32.0634920634921, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1787924, Length=288, Percent_Identity=54.5138888888889, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1788758, Length=266, Percent_Identity=30.4511278195489, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17507759, Length=293, Percent_Identity=33.4470989761092, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17507757, Length=302, Percent_Identity=32.7814569536424, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320806, Length=236, Percent_Identity=33.4745762711864, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324354, Length=169, Percent_Identity=36.094674556213, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45553007, Length=308, Percent_Identity=30.5194805194805, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31334; Mature: 31334

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILSIQSHVVFGCAGNSAAVFPMRRMGMEVWPINTVQFSNHTQYLQGWKGIAMPAGHI
CCCHHEECCEEEEEECCCCCEECHHHHCCCEEECCCEEEECCCHHHHHCCCCCCCCHHHH
SELVDGLSAIEATKVCDAVLSGYLGSAAQGQEIITAVKKIKQDNSNAIYFCDPVMGHPEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVAPEVEVFFKESALASADIIAPNLLELESLSGMTINTLEQVIEANNQLLEKGVKMVV
CCEECCCHHEEEHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKHLSRAGIKKDRFEMLLTTKDGSYHISRPLYDFDAKRQPVGAGDLISGVMLANLIAGCS
HHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PIDAFERTNAAVDSVMKETFKQGAYELQLIASQEQFNAPNITVKATKVA
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MKRILSIQSHVVFGCAGNSAAVFPMRRMGMEVWPINTVQFSNHTQYLQGWKGIAMPAGHI
CCCHHEECCEEEEEECCCCCEECHHHHCCCEEECCCEEEECCCHHHHHCCCCCCCCHHHH
SELVDGLSAIEATKVCDAVLSGYLGSAAQGQEIITAVKKIKQDNSNAIYFCDPVMGHPEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVAPEVEVFFKESALASADIIAPNLLELESLSGMTINTLEQVIEANNQLLEKGVKMVV
CCEECCCHHEEEHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKHLSRAGIKKDRFEMLLTTKDGSYHISRPLYDFDAKRQPVGAGDLISGVMLANLIAGCS
HHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PIDAFERTNAAVDSVMKETFKQGAYELQLIASQEQFNAPNITVKATKVA
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA