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The map label for this gene is tsf

Identifier: 209695850

GI number: 209695850

Start: 2596349

End: 2597197

Strand: Reverse

Name: tsf

Synonym: VSAL_I2426

Alternate gene names: 209695850

Gene position: 2597197-2596349 (Counterclockwise)

Preceding gene: 209695851

Following gene: 209695849

Centisome position: 78.11

GC content: 43.23

Gene sequence:

>849_bases
ATGGCAACTGTAACTGCTGCTCTAGTTAAAGAACTTCGTGAACGTACTGCTGCTGGCATGATGGAGTGTAAAAAAGCACT
TGTTGAAGCTGAAGGCGACATCGAATTAGCAATTGAAAATATGCGTAAATCTGGCGCAGCAAAAGCGGCTAAGAAAGCAG
GCAACATCGCTGCTGAAGGGACAATCATCATTAAAGAAGAAGCTGGCGTAGCCGTTCTTCTTGAAGTTAACTGTCAAACT
GATTTCGTAGCTAAAGATTCTGGTTTCCTAGGATTTGCTAACGAAGTTGCAGAAGTTGCTCTAGCAGAACGTCTAAACGA
CATCGTTGCTCTTCAAGCTAAATTTGAAGATGCTCGTATCGCTCTAGTTACTAAAATTGGCGAAAACATCAGCATCCGTC
GCGTTCAACTAGTTGAAGGCGTTGCACTAGCTTCTTACCGTCACGGCGAGAAAATCGGTGTTGTTATTGCTGGTGAAGGC
GATGCTGAAACACTTAAGCACATCGCTATGCACGTTGCTGCCTCTAAGCCTGAATACGTTAACCCATCTGACGTACCAGC
TGACGTTGTAGAAAAAGAAAAAGCAGTTCAAGTAGAAATCGCTATGAACGAAGGCAAGCCTCAAGAAATCGCAGAGAAAA
TGGTTATCGGCCGTATGAAGAAATTCACAGGCGAAGTTTCTCTAACAGGTCAAGCTTTCATCATGGAACCTAAGAAAACT
GTTGCTGACATTCTTAAAGAAAAAGGCGCATCAGTATCTAACTTCGTACGTTTAGAAGTTGGTGAAGGTATCGAGAAAGC
GGCTGAAATGAGCTTTGCTGACGAAGTAGCAGCAGTACAAAAAGGTTAA

Upstream 100 bases:

>100_bases
GTGAGTCTTTTAGTTTCGTAGTAAACTAAAAATAGTTAGCAGGGGCCCAATTTGGCCCCTGATTTTTAACTTTAAATCTA
TTTATATTGAGGCATTGAGA

Downstream 100 bases:

>100_bases
TCCTTACGTATTGTTGAAAAAAGAGACCGTGGCTTTGCTGCGGTCTTTTTGTGAATGCGACATAAAGATTTAATCAATAG
GCAAATGATAGTTGTAACTT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MATVTAALVKELRERTAAGMMECKKALVEAEGDIELAIENMRKSGAAKAAKKAGNIAAEGTIIIKEEAGVAVLLEVNCQT
DFVAKDSGFLGFANEVAEVALAERLNDIVALQAKFEDARIALVTKIGENISIRRVQLVEGVALASYRHGEKIGVVIAGEG
DAETLKHIAMHVAASKPEYVNPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKT
VADILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG

Sequences:

>Translated_282_residues
MATVTAALVKELRERTAAGMMECKKALVEAEGDIELAIENMRKSGAAKAAKKAGNIAAEGTIIIKEEAGVAVLLEVNCQT
DFVAKDSGFLGFANEVAEVALAERLNDIVALQAKFEDARIALVTKIGENISIRRVQLVEGVALASYRHGEKIGVVIAGEG
DAETLKHIAMHVAASKPEYVNPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKT
VADILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG
>Mature_281_residues
ATVTAALVKELRERTAAGMMECKKALVEAEGDIELAIENMRKSGAAKAAKKAGNIAAEGTIIIKEEAGVAVLLEVNCQTD
FVAKDSGFLGFANEVAEVALAERLNDIVALQAKFEDARIALVTKIGENISIRRVQLVEGVALASYRHGEKIGVVIAGEGD
AETLKHIAMHVAASKPEYVNPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKTV
ADILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=290, Percent_Identity=25.5172413793103, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1786366, Length=282, Percent_Identity=66.3120567375886, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17561440, Length=292, Percent_Identity=23.6301369863014, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19921466, Length=284, Percent_Identity=25.7042253521127, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_ALISL (B6EK56)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263780.1
- GeneID:   6989053
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2426
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30021; Mature: 29890

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVTAALVKELRERTAAGMMECKKALVEAEGDIELAIENMRKSGAAKAAKKAGNIAAEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECC
TIIIKEEAGVAVLLEVNCQTDFVAKDSGFLGFANEVAEVALAERLNDIVALQAKFEDARI
EEEEEECCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEE
ALVTKIGENISIRRVQLVEGVALASYRHGEKIGVVIAGEGDAETLKHIAMHVAASKPEYV
EEEEECCCCCEEEEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
NPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKT
CCCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEECCHHH
VADILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG
HHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATVTAALVKELRERTAAGMMECKKALVEAEGDIELAIENMRKSGAAKAAKKAGNIAAEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECC
TIIIKEEAGVAVLLEVNCQTDFVAKDSGFLGFANEVAEVALAERLNDIVALQAKFEDARI
EEEEEECCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEE
ALVTKIGENISIRRVQLVEGVALASYRHGEKIGVVIAGEGDAETLKHIAMHVAASKPEYV
EEEEECCCCCEEEEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
NPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKT
CCCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEECCHHH
VADILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG
HHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA