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The map label for this gene is frr

Identifier: 209695848

GI number: 209695848

Start: 2594855

End: 2595412

Strand: Reverse

Name: frr

Synonym: VSAL_I2424

Alternate gene names: 209695848

Gene position: 2595412-2594855 (Counterclockwise)

Preceding gene: 209695849

Following gene: 209695847

Centisome position: 78.05

GC content: 37.99

Gene sequence:

>558_bases
GTGATTAACGAAATTAAAAAAGACGCTCAAGAGCGTATGGAAAAAAGCGTAGAAGCACTGAAAAATAACCTGTTAAAAAT
TCGTACAGGTCGTGCTCACCCAAGCCTTCTATCTGGTCTTAGTGTTGAGTATTATGGTGCAAGAACACCAATCAACCAAG
TAGCTAACATCATTGCTGAAGATTCTCGTACTCTTGCAATTACTGTTTTTGACAAAGAACTTGCTGGTCTTGTTGAAAAA
GCGATCATGATGTCTGATCTGGGTTTAAACCCTATGTCTGCGGGTACGGTAATTCGTGTACCACTTCCACCATTAACTGA
AGAACGTCGTAAAAGTCTTGTTAAGATTGTACGTGGTGAAGCTGAAAATGGTCGTGTTGCCGTTCGTAATATTCGTCGTG
ATGCAAACGGTGATATTAAAGCGCTTCTTAAAGATAAAGAAATCTCAGAAGATGATGATCGTAGAACACAAGACGAGATT
CAAAAACTAACAGACATCGCTGTTAAAAATATTGATGATGTACTTGCTGTTAAAGAAAAAGAGTTAATGGAAGTATAA

Upstream 100 bases:

>100_bases
CCTGGTGCATTACGTCGTGTAGTAATGGGTGAGGCAGAAGGTACTTTAATCAGCAGTGCTGAATAATTGTCTGTAATAAA
ATAACATTTAAGGTGAAGTT

Downstream 100 bases:

>100_bases
TTTACTTTTATTACTCATAGTTCAGGCTGATTTTTATCTATTTTTAGTGGTATGATGACGGCGATGAACACTGTAAGAAG
CGCTATGTGCAGACATCAGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGEAENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEI
QKLTDIAVKNIDDVLAVKEKELMEV

Sequences:

>Translated_185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGEAENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEI
QKLTDIAVKNIDDVLAVKEKELMEV
>Mature_185_residues
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAEDSRTLAITVFDKELAGLVEK
AIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGEAENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEI
QKLTDIAVKNIDDVLAVKEKELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=31.8435754189944, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=33.0882352941176, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=68.6486486486486, Blast_Score=257, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ALISL (B6EK54)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263778.1
- GeneID:   6989359
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2424
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20672; Mature: 20672

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAE
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCCCHHHHHHHHHC
DSRTLAITVFDKELAGLVEKAIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGE
CCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEIQKLTDIAVKNIDDVLAVKEK
CCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAE
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCEEECCCCCCHHHHHHHHHC
DSRTLAITVFDKELAGLVEKAIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGE
CCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEIQKLTDIAVKNIDDVLAVKEK
CCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA