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The map label for this gene is sixA [H]

Identifier: 209695604

GI number: 209695604

Start: 2328370

End: 2328840

Strand: Direct

Name: sixA [H]

Synonym: VSAL_I2165

Alternate gene names: 209695604

Gene position: 2328370-2328840 (Clockwise)

Preceding gene: 209695603

Following gene: 209695606

Centisome position: 70.02

GC content: 39.28

Gene sequence:

>471_bases
ATGAAAGTATTCATAATGCGTCATGGTGAAGCTGAAGCGTATGCAGCCTCTGATGAAGAGCGTAATTTAACATCGCACGG
TGAAAGCCAATCAGCCGTAATTGCCAACTGGTTAATGAAAACACATCAAGTTGCTTTTGATTATGTATTAGTCAGCCCTT
ATGTTCGAGCACAACAAACATGGCAAGTGATTAAGCCAATATTAAATGTGGCAAAGGCTAAGGTAGAAATATCAGATGAG
ATAACACCTTATGGTGATTCTGATGATGTTGTAGAGTACGTAAAAGCATTAGGCAGCGTTGAAGCGATTAATAATGTATT
AATTGTGTCTCATTTGCCATTAGTTGGGTATTTAACGGCTGATTTTGTTCCGGGGATTATGCCGCCAATGTTTCCTACAT
CGGCTATTTCGTGTGTTGAGTTTTCTCATCAGACAGGAAAAAGCGATTTATTGTGGTTACAGCAGCCATAA

Upstream 100 bases:

>100_bases
ATTATGGCGCTGATACCACAGAGTAGCAAACTCTCTCTTTCCTCTTTTTTCAATTGCTTGCTACTATTGTGAGGTTAGTA
ATGATTTTGAGAATGATTCA

Downstream 100 bases:

>100_bases
ATAAAGAGAGATAATTTGAGGGTACGTTATTCCCTCAAATTATATTATCGGTCTGGGATCGAAAGTAAAACTAAAATGGC
GCCTGCGCCACCAAATTCTA

Product: phosphohistidine phosphatase SixA

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKVFIMRHGEAEAYAASDEERNLTSHGESQSAVIANWLMKTHQVAFDYVLVSPYVRAQQTWQVIKPILNVAKAKVEISDE
ITPYGDSDDVVEYVKALGSVEAINNVLIVSHLPLVGYLTADFVPGIMPPMFPTSAISCVEFSHQTGKSDLLWLQQP

Sequences:

>Translated_156_residues
MKVFIMRHGEAEAYAASDEERNLTSHGESQSAVIANWLMKTHQVAFDYVLVSPYVRAQQTWQVIKPILNVAKAKVEISDE
ITPYGDSDDVVEYVKALGSVEAINNVLIVSHLPLVGYLTADFVPGIMPPMFPTSAISCVEFSHQTGKSDLLWLQQP
>Mature_156_residues
MKVFIMRHGEAEAYAASDEERNLTSHGESQSAVIANWLMKTHQVAFDYVLVSPYVRAQQTWQVIKPILNVAKAKVEISDE
ITPYGDSDDVVEYVKALGSVEAINNVLIVSHLPLVGYLTADFVPGIMPPMFPTSAISCVEFSHQTGKSDLLWLQQP

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=156, Percent_Identity=46.1538461538462, Blast_Score=133, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 17292; Mature: 17292

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFIMRHGEAEAYAASDEERNLTSHGESQSAVIANWLMKTHQVAFDYVLVSPYVRAQQT
CEEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
WQVIKPILNVAKAKVEISDEITPYGDSDDVVEYVKALGSVEAINNVLIVSHLPLVGYLTA
HHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCHHHHHHH
DFVPGIMPPMFPTSAISCVEFSHQTGKSDLLWLQQP
HHCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure
MKVFIMRHGEAEAYAASDEERNLTSHGESQSAVIANWLMKTHQVAFDYVLVSPYVRAQQT
CEEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
WQVIKPILNVAKAKVEISDEITPYGDSDDVVEYVKALGSVEAINNVLIVSHLPLVGYLTA
HHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCHHHHHHH
DFVPGIMPPMFPTSAISCVEFSHQTGKSDLLWLQQP
HHCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]