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The map label for this gene is hlyB [H]

Identifier: 209695411

GI number: 209695411

Start: 2088186

End: 2090348

Strand: Direct

Name: hlyB [H]

Synonym: VSAL_I1951

Alternate gene names: 209695411

Gene position: 2088186-2090348 (Clockwise)

Preceding gene: 209695410

Following gene: 209695417

Centisome position: 62.8

GC content: 38.51

Gene sequence:

>2163_bases
ATGAACTCATATATAGAAGGATATTGTATGCAGTCACTTTCTCTTCAGTGGAAAATAACCATCGCGGCAGCCATTGGGCT
TATTACTCTTGCTTCTTCGCTCATTGGTTTTTCCATTTATTCCTCGATTGAAAATCAAGTGGTTGTTCAAAAGCAGACGT
CAGATTCTGTTATTAAGCAAACTCAAACGCTATTAATGGCAGAAGCAAAAAATCAATCAAAACAAATTCAAACTTACTTA
GATGAAGCGATTTATCGAGCTGAAATGCTTGCTGAAAGTGCGCTGTTTTTTCAACAAAGTGCTGAAGATACCTTTATGGA
CAGTGGTGACTTACGCCAGTCTTTAAGTGACATGATGAAGAGACCAGTACAGAAATACCCTAATATTTATGGTGCATACA
GCGTATATCAACCAGATATGTTAGATGGAGAAGATTTTAATTATCATGATGCAGGTTATGCGAGTTCAAATAAAATAGGG
CGCTTTGCTCCTTATTGGTTTAAATCAGCAACCAAAGAAGCTGAAATGCGTGTCTTTACAGAAAAAGAGCTGAGTAACAC
AGAAAGAGAAGCGAGCGGAGATGCGTCGAATTACTGGTTTACGTGTAGTTTAAAAGAAAGCCGTTTGTGCATTATTGATC
CTTATTATTATGAAAATAATGGGGTAACGACACTTATCAGTTCTATTACCACTCCTTTGATAAAAGAAGGACAAACAATA
GGAATTATTGGTATTGACCTTGATATAGGTCGTCTTTCTGACCTAGTCACTCAAGCTGATAACGCTATTTTCAATGGTGA
TGGTGCGATTTATGTCGTCAATGGAAAAGGAAAACTCATATTATCAGATCAGAAAAACACCTCTTTTGGCCAATCTTTAG
ATTCACATAATAATACATTATCAATGGTACCTTCGTGGGTCTCTGCTGGAAACTCACAATTAATATGGTCTGATAATAAA
AATAAGTTGTTTGTGTTTGTGCCAATCAATTTAAAAACACAGCGTTGGGGAGTCATTATTGAAGTCGATAGAGAAACGGT
GTTTGCAGATGTCAATAAATTAGACCGTTTACTTATTGAACATGGGAGTGAATCTTTATTAATGCAAGGAATGGTTGGTT
TAGTCTTAACCGTTTTAGTGTTAACTGCTTTATGGTTTGCCACGAAACAGATTGTAAAACCTATTTCATTAGTGGCTTTA
CGTTTAAAAGATATCGCTTCTGGTGAAGGGGATTTAACCCAACGCTTGGCTGTACAAAGTAAAGATGAAGTAGGGCAATT
GGCGCATTGGTTTAATGCTTTTTTAGAAAAACTTCAATTAACAATTAAAGATGTGGCTCAAAGCAGTGATGAATTATCGA
ATGTAGCTGCGCGATCAAGTTCTATTGCGAGCCAATCTAAAGAAGGCAGCGATGTTCAATTTCGAGAAGTCGATATGGTT
GCTACTGCGGTGGAAGAGTTAACACAAACGGCAAGCTTAGTGGTTGATCATTCAACACTCGCCGCTGATGCTGCAAAGCA
AGCAGAATCGGCTTCTAATGAAGGAAAAGAATTAATATTGACGACTGAGTCCGTTATTCAATTTTTAGTCAGTAATATGG
AAAAAGCGGTCCCTGTTGCTCAGGAATTAGAGTGTAATAGCTCAAATATAACCGCCATATTATCGGTTATTGAGGGAATA
TCTGAACAGACTAACTTACTTGCATTGAATGCGGCGATTGAAGCAGCGAGAGCGGGGGAGCAAGGAAGAGGATTTGCTGT
TGTGGCTGATGAAGTTCGTCAGTTAGCAAGACGTACCGGAGATTCTGTGGATGAAATTCGCATAGTGATTGAGAAGTTAC
AATCAGGAACTAAATCGGTTGTAACTGCAATCACTGAGGGAAATACGATTGCACTGGATGGCGCATCGACGATTAAATTG
TCGGTAGAAAGCCTGCAACAAATCAGTGCGGCTGTTGTGACAATACAGGACATGAATATGCAAATTGTGAGAGCCGCAGA
AGAGCAGCAAGCCGTTTCTAATGAAGTGAATCAAAGTGTCAGTAATATCCGAGATTCAAGCCATAAGATGTTAGAACAAG
CCAATTCTGGTGAAGCGGTAGGTTTAGAGCTTTCATCGTTATCAACGCAACAAAAACAATTGATGTCCCAATTTAAAGTT
TAA

Upstream 100 bases:

>100_bases
TCTAAATGTTTAAATTTGGTTAAATATTATTAGCAAACTGTCGATAAAGAAAGGTAAGTATTTTAATTGGCTATTTTAGT
TAAAAAATAAATAGATTTTA

Downstream 100 bases:

>100_bases
CTGTCGAAACGGTGTAAATAAAAAACGCCCATGGGATGAAACCTATGGGCGTTATTATTTAATCCGTACAATTCATTGTG
ATTGTATTGATTATATGATC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MNSYIEGYCMQSLSLQWKITIAAAIGLITLASSLIGFSIYSSIENQVVVQKQTSDSVIKQTQTLLMAEAKNQSKQIQTYL
DEAIYRAEMLAESALFFQQSAEDTFMDSGDLRQSLSDMMKRPVQKYPNIYGAYSVYQPDMLDGEDFNYHDAGYASSNKIG
RFAPYWFKSATKEAEMRVFTEKELSNTEREASGDASNYWFTCSLKESRLCIIDPYYYENNGVTTLISSITTPLIKEGQTI
GIIGIDLDIGRLSDLVTQADNAIFNGDGAIYVVNGKGKLILSDQKNTSFGQSLDSHNNTLSMVPSWVSAGNSQLIWSDNK
NKLFVFVPINLKTQRWGVIIEVDRETVFADVNKLDRLLIEHGSESLLMQGMVGLVLTVLVLTALWFATKQIVKPISLVAL
RLKDIASGEGDLTQRLAVQSKDEVGQLAHWFNAFLEKLQLTIKDVAQSSDELSNVAARSSSIASQSKEGSDVQFREVDMV
ATAVEELTQTASLVVDHSTLAADAAKQAESASNEGKELILTTESVIQFLVSNMEKAVPVAQELECNSSNITAILSVIEGI
SEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLARRTGDSVDEIRIVIEKLQSGTKSVVTAITEGNTIALDGASTIKL
SVESLQQISAAVVTIQDMNMQIVRAAEEQQAVSNEVNQSVSNIRDSSHKMLEQANSGEAVGLELSSLSTQQKQLMSQFKV

Sequences:

>Translated_720_residues
MNSYIEGYCMQSLSLQWKITIAAAIGLITLASSLIGFSIYSSIENQVVVQKQTSDSVIKQTQTLLMAEAKNQSKQIQTYL
DEAIYRAEMLAESALFFQQSAEDTFMDSGDLRQSLSDMMKRPVQKYPNIYGAYSVYQPDMLDGEDFNYHDAGYASSNKIG
RFAPYWFKSATKEAEMRVFTEKELSNTEREASGDASNYWFTCSLKESRLCIIDPYYYENNGVTTLISSITTPLIKEGQTI
GIIGIDLDIGRLSDLVTQADNAIFNGDGAIYVVNGKGKLILSDQKNTSFGQSLDSHNNTLSMVPSWVSAGNSQLIWSDNK
NKLFVFVPINLKTQRWGVIIEVDRETVFADVNKLDRLLIEHGSESLLMQGMVGLVLTVLVLTALWFATKQIVKPISLVAL
RLKDIASGEGDLTQRLAVQSKDEVGQLAHWFNAFLEKLQLTIKDVAQSSDELSNVAARSSSIASQSKEGSDVQFREVDMV
ATAVEELTQTASLVVDHSTLAADAAKQAESASNEGKELILTTESVIQFLVSNMEKAVPVAQELECNSSNITAILSVIEGI
SEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLARRTGDSVDEIRIVIEKLQSGTKSVVTAITEGNTIALDGASTIKL
SVESLQQISAAVVTIQDMNMQIVRAAEEQQAVSNEVNQSVSNIRDSSHKMLEQANSGEAVGLELSSLSTQQKQLMSQFKV
>Mature_720_residues
MNSYIEGYCMQSLSLQWKITIAAAIGLITLASSLIGFSIYSSIENQVVVQKQTSDSVIKQTQTLLMAEAKNQSKQIQTYL
DEAIYRAEMLAESALFFQQSAEDTFMDSGDLRQSLSDMMKRPVQKYPNIYGAYSVYQPDMLDGEDFNYHDAGYASSNKIG
RFAPYWFKSATKEAEMRVFTEKELSNTEREASGDASNYWFTCSLKESRLCIIDPYYYENNGVTTLISSITTPLIKEGQTI
GIIGIDLDIGRLSDLVTQADNAIFNGDGAIYVVNGKGKLILSDQKNTSFGQSLDSHNNTLSMVPSWVSAGNSQLIWSDNK
NKLFVFVPINLKTQRWGVIIEVDRETVFADVNKLDRLLIEHGSESLLMQGMVGLVLTVLVLTALWFATKQIVKPISLVAL
RLKDIASGEGDLTQRLAVQSKDEVGQLAHWFNAFLEKLQLTIKDVAQSSDELSNVAARSSSIASQSKEGSDVQFREVDMV
ATAVEELTQTASLVVDHSTLAADAAKQAESASNEGKELILTTESVIQFLVSNMEKAVPVAQELECNSSNITAILSVIEGI
SEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLARRTGDSVDEIRIVIEKLQSGTKSVVTAITEGNTIALDGASTIKL
SVESLQQISAAVVTIQDMNMQIVRAAEEQQAVSNEVNQSVSNIRDSSHKMLEQANSGEAVGLELSSLSTQQKQLMSQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=314, Percent_Identity=31.8471337579618, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI2367378, Length=329, Percent_Identity=30.6990881458967, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=30.0578034682081, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=304, Percent_Identity=29.2763157894737, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1789453, Length=286, Percent_Identity=33.5664335664336, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 78818; Mature: 78818

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYIEGYCMQSLSLQWKITIAAAIGLITLASSLIGFSIYSSIENQVVVQKQTSDSVIKQ
CCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
TQTLLMAEAKNQSKQIQTYLDEAIYRAEMLAESALFFQQSAEDTFMDSGDLRQSLSDMMK
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
RPVQKYPNIYGAYSVYQPDMLDGEDFNYHDAGYASSNKIGRFAPYWFKSATKEAEMRVFT
HHHHHCCCCEECEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHEEE
EKELSNTEREASGDASNYWFTCSLKESRLCIIDPYYYENNGVTTLISSITTPLIKEGQTI
HHHHCCCHHHCCCCCCCEEEEEEECCCCEEEECCEEEECCCHHHHHHHHHHHHHHCCCEE
GIIGIDLDIGRLSDLVTQADNAIFNGDGAIYVVNGKGKLILSDQKNTSFGQSLDSHNNTL
EEEEEECCHHHHHHHHHHHCCCEECCCCEEEEECCCCEEEEECCCCCCHHCCHHCCCCEE
SMVPSWVSAGNSQLIWSDNKNKLFVFVPINLKTQRWGVIIEVDRETVFADVNKLDRLLIE
EECCHHHCCCCCEEEEECCCCEEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
HGSESLLMQGMVGLVLTVLVLTALWFATKQIVKPISLVALRLKDIASGEGDLTQRLAVQS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
KDEVGQLAHWFNAFLEKLQLTIKDVAQSSDELSNVAARSSSIASQSKEGSDVQFREVDMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ATAVEELTQTASLVVDHSTLAADAAKQAESASNEGKELILTTESVIQFLVSNMEKAVPVA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCH
QELECNSSNITAILSVIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLARRTG
HHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCC
DSVDEIRIVIEKLQSGTKSVVTAITEGNTIALDGASTIKLSVESLQQISAAVVTIQDMNM
CCHHHHHHHHHHHHCCHHHHHEEEECCCEEEECCCCEEEEEHHHHHHHHHHEEEEECCCH
QIVRAAEEQQAVSNEVNQSVSNIRDSSHKMLEQANSGEAVGLELSSLSTQQKQLMSQFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MNSYIEGYCMQSLSLQWKITIAAAIGLITLASSLIGFSIYSSIENQVVVQKQTSDSVIKQ
CCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHH
TQTLLMAEAKNQSKQIQTYLDEAIYRAEMLAESALFFQQSAEDTFMDSGDLRQSLSDMMK
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
RPVQKYPNIYGAYSVYQPDMLDGEDFNYHDAGYASSNKIGRFAPYWFKSATKEAEMRVFT
HHHHHCCCCEECEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHEEE
EKELSNTEREASGDASNYWFTCSLKESRLCIIDPYYYENNGVTTLISSITTPLIKEGQTI
HHHHCCCHHHCCCCCCCEEEEEEECCCCEEEECCEEEECCCHHHHHHHHHHHHHHCCCEE
GIIGIDLDIGRLSDLVTQADNAIFNGDGAIYVVNGKGKLILSDQKNTSFGQSLDSHNNTL
EEEEEECCHHHHHHHHHHHCCCEECCCCEEEEECCCCEEEEECCCCCCHHCCHHCCCCEE
SMVPSWVSAGNSQLIWSDNKNKLFVFVPINLKTQRWGVIIEVDRETVFADVNKLDRLLIE
EECCHHHCCCCCEEEEECCCCEEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
HGSESLLMQGMVGLVLTVLVLTALWFATKQIVKPISLVALRLKDIASGEGDLTQRLAVQS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
KDEVGQLAHWFNAFLEKLQLTIKDVAQSSDELSNVAARSSSIASQSKEGSDVQFREVDMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ATAVEELTQTASLVVDHSTLAADAAKQAESASNEGKELILTTESVIQFLVSNMEKAVPVA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCH
QELECNSSNITAILSVIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLARRTG
HHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCC
DSVDEIRIVIEKLQSGTKSVVTAITEGNTIALDGASTIKLSVESLQQISAAVVTIQDMNM
CCHHHHHHHHHHHHCCHHHHHEEEECCCEEEECCCCEEEEEHHHHHHHHHHEEEEECCCH
QIVRAAEEQQAVSNEVNQSVSNIRDSSHKMLEQANSGEAVGLELSSLSTQQKQLMSQFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]