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The map label for this gene is hflX [H]

Identifier: 209695380

GI number: 209695380

Start: 2047714

End: 2049075

Strand: Direct

Name: hflX [H]

Synonym: VSAL_I1914

Alternate gene names: 209695380

Gene position: 2047714-2049075 (Clockwise)

Preceding gene: 209695379

Following gene: 209695381

Centisome position: 61.58

GC content: 40.68

Gene sequence:

>1362_bases
ATGAAACTAACAGAAAAAGCATCACTTACTAATGCTTTACTTATTTCTATCTGCACACCGCAGTTTAAAGGTGATGAGGC
AAAAGACTCACTTGCAGAACTTGCTCGCTTAGTGACTACCCTAGGGTTTAAAGTCGTCGGTACGCAGTCGCAAAAACAAA
GTTCTACTCAAAAAGTGAATGTTCTGGGGTCTGGTAAATTGGCTGAAATAGCGCATCTTACTGGTAATCAAGGCGAGAGT
GATGACGCTGATACTGAAGATTTCTTTGATGAGACAGATTTTGACGACGTTCCTTCAGAAGATCTGCCATTTGCATGCGC
TGATGTAGTGGTATTTGATTGCGATTTAAGTCCGTCACAGTTACGTAATGTCGAAAACCAATTAGGCATTAGAGTGTATG
ACCGTACCGGGATTATTATTGAAATCTTTAGTCGTCACGCTCGTACTCGAACAGCACGTTTACAAGTTGAAATGGCTCGC
CTTAATTATGTCGCACCGCGATTAAGAGAATCGACCATTGGTGATAACGAACGCCAAATGGGTAAAGGTGCCGGTGAAAC
AGATCTAGAGCTAGATCGCCGTAAAGTTCGAGATCAATTAGCTGAATTACGTCGAGAGTTAGAAAGCGTTCAAGGTGAGC
TGAAAGGCCGCCGTAAACAACGTTCAGAGCTTTTCTGTGTGGCTTTAGTTGGGTATACCAATGCCGGTAAATCCTCCATG
ATGCGAGCGCTTACGGGAAGTGAAGTATTAGTAGAAGATAAACTTTTTGCTACGCTTGATACGACTGTACGTGCACTCTA
TCCAGTTACTCAGCCTCGTATCTTAGTATCAGATACTGTTGGTTTTATTAAAAAGCTGCCTCACGACTTAGTTGCCTCAT
TTCACTCAACACTAGCGGAAGCACATGATGCTTCATTACTGCTTTATGTTGTTGATGCCTCTGATGCGTCTTTCCGTACA
CAACTTGATGTTGTGCATGAAGTACTAAAAGAAGTCGGGGTTGAAGACGTTAAGAAACTACTTGTACTTAATAAATCAGA
CCAATTGACTGTTGAGCAACAAGAAGAGTTAATGGAAGAGTTTCCTGATGCGATGATGACGTCAACTCGAAACCCTCTTG
ATATTGCTAAACTGCACAAATATATCGTTGGTGTTTCTCAACATGAAATGATTGAAGAAGAGATCATTGTGCCTTATACC
GCTAAAGGTATTATTGGGGAAATTCGTTCAAGCATGAGTGTCGTTAAAGAAGAATATGAATACAGTCATATTAAACTGAC
AGTACGATCAAGTGCCATTGACTTAGCAAGATTAGAAAAGTTAATGTCGAATTTAGACGAAGAAAATAACGAAGAGTTAT
AA

Upstream 100 bases:

>100_bases
TTTAGTGTTCTATTCCTCTATAAAGCTCATCTATAACAGCGTAGGATCAGGTAACTTTAGATAAAACCAAGTTTGCACTT
AGGTGCACTAAGAGAAAATA

Downstream 100 bases:

>100_bases
GTCTACGTTTCGTGTGTACTGATAGAGGTTGAAGGTATTAATGCTTTCAATCTCTATAACATACCCTAATACTAATTTGA
TAATAAATATAGCGTGAGTA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKLTEKASLTNALLISICTPQFKGDEAKDSLAELARLVTTLGFKVVGTQSQKQSSTQKVNVLGSGKLAEIAHLTGNQGES
DDADTEDFFDETDFDDVPSEDLPFACADVVVFDCDLSPSQLRNVENQLGIRVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESTIGDNERQMGKGAGETDLELDRRKVRDQLAELRRELESVQGELKGRRKQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVEDKLFATLDTTVRALYPVTQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDASFRT
QLDVVHEVLKEVGVEDVKKLLVLNKSDQLTVEQQEELMEEFPDAMMTSTRNPLDIAKLHKYIVGVSQHEMIEEEIIVPYT
AKGIIGEIRSSMSVVKEEYEYSHIKLTVRSSAIDLARLEKLMSNLDEENNEEL

Sequences:

>Translated_453_residues
MKLTEKASLTNALLISICTPQFKGDEAKDSLAELARLVTTLGFKVVGTQSQKQSSTQKVNVLGSGKLAEIAHLTGNQGES
DDADTEDFFDETDFDDVPSEDLPFACADVVVFDCDLSPSQLRNVENQLGIRVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESTIGDNERQMGKGAGETDLELDRRKVRDQLAELRRELESVQGELKGRRKQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVEDKLFATLDTTVRALYPVTQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDASFRT
QLDVVHEVLKEVGVEDVKKLLVLNKSDQLTVEQQEELMEEFPDAMMTSTRNPLDIAKLHKYIVGVSQHEMIEEEIIVPYT
AKGIIGEIRSSMSVVKEEYEYSHIKLTVRSSAIDLARLEKLMSNLDEENNEEL
>Mature_453_residues
MKLTEKASLTNALLISICTPQFKGDEAKDSLAELARLVTTLGFKVVGTQSQKQSSTQKVNVLGSGKLAEIAHLTGNQGES
DDADTEDFFDETDFDDVPSEDLPFACADVVVFDCDLSPSQLRNVENQLGIRVYDRTGIIIEIFSRHARTRTARLQVEMAR
LNYVAPRLRESTIGDNERQMGKGAGETDLELDRRKVRDQLAELRRELESVQGELKGRRKQRSELFCVALVGYTNAGKSSM
MRALTGSEVLVEDKLFATLDTTVRALYPVTQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYVVDASDASFRT
QLDVVHEVLKEVGVEDVKKLLVLNKSDQLTVEQQEELMEEFPDAMMTSTRNPLDIAKLHKYIVGVSQHEMIEEEIIVPYT
AKGIIGEIRSSMSVVKEEYEYSHIKLTVRSSAIDLARLEKLMSNLDEENNEEL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI310124269, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310124267, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310124171, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310124169, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310133118, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790615, Length=446, Percent_Identity=32.9596412556054, Blast_Score=205, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17561038, Length=228, Percent_Identity=34.2105263157895, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650079, Length=310, Percent_Identity=30.3225806451613, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50627; Mature: 50627

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTEKASLTNALLISICTPQFKGDEAKDSLAELARLVTTLGFKVVGTQSQKQSSTQKVN
CCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHCCCCEEE
VLGSGKLAEIAHLTGNQGESDDADTEDFFDETDFDDVPSEDLPFACADVVVFDCDLSPSQ
EECCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
LRNVENQLGIRVYDRTGIIIEIFSRHARTRTARLQVEMARLNYVAPRLRESTIGDNERQM
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GKGAGETDLELDRRKVRDQLAELRRELESVQGELKGRRKQRSELFCVALVGYTNAGKSSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHH
MRALTGSEVLVEDKLFATLDTTVRALYPVTQPRILVSDTVGFIKKLPHDLVASFHSTLAE
HHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
AHDASLLLYVVDASDASFRTQLDVVHEVLKEVGVEDVKKLLVLNKSDQLTVEQQEELMEE
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHH
FPDAMMTSTRNPLDIAKLHKYIVGVSQHEMIEEEIIVPYTAKGIIGEIRSSMSVVKEEYE
CCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHC
YSHIKLTVRSSAIDLARLEKLMSNLDEENNEEL
CEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLTEKASLTNALLISICTPQFKGDEAKDSLAELARLVTTLGFKVVGTQSQKQSSTQKVN
CCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHCCCCEEE
VLGSGKLAEIAHLTGNQGESDDADTEDFFDETDFDDVPSEDLPFACADVVVFDCDLSPSQ
EECCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
LRNVENQLGIRVYDRTGIIIEIFSRHARTRTARLQVEMARLNYVAPRLRESTIGDNERQM
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GKGAGETDLELDRRKVRDQLAELRRELESVQGELKGRRKQRSELFCVALVGYTNAGKSSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHH
MRALTGSEVLVEDKLFATLDTTVRALYPVTQPRILVSDTVGFIKKLPHDLVASFHSTLAE
HHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
AHDASLLLYVVDASDASFRTQLDVVHEVLKEVGVEDVKKLLVLNKSDQLTVEQQEELMEE
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHH
FPDAMMTSTRNPLDIAKLHKYIVGVSQHEMIEEEIIVPYTAKGIIGEIRSSMSVVKEEYE
CCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHC
YSHIKLTVRSSAIDLARLEKLMSNLDEENNEEL
CEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]